抗生素军团告人类战友书

引用本文: 孙吉峻, 王黔浪, 陈前, 赵全芹, 翟淑梅. 抗生素军团告人类战友书[J]. 大学化学, 2025, 40(4): 307-321. doi: 10.12461/PKU.DXHX202405206 shu

Citation: Jijun Sun, Qianlang Wang, Qian Chen, Quanqin Zhao, Shumei Zhai. The Antibiotic Legion’s Manifesto to Human Allies[J]. University Chemistry, 2025, 40(4): 307-321. doi: 10.12461/PKU.DXHX202405206 shu

抗生素军团告人类战友书

1.
山东大学第二医院, 济南 250033;
2.
济南护理职业学院, 济南 250102;
3.
山东大学化学与化工学院, 济南 250100
基金项目:
国家重点研发计划课题(2023YFA0915103)

摘要: 运用拟人化手法，生动形象地介绍抗生素的发现史、分类、作用机制、对人体的不良反应及使用抗生素的注意事项，旨在让读者在趣味阅读中了解有关抗生素的基础知识。

关键词:

抗生素
/ 抗菌药
/ 科普

English

The Antibiotic Legion’s Manifesto to Human Allies

1.
The Second Hospital of Shandong University, Jinan 250033, China;
2.
Jinan Vocational College of Nursing, Jinan 250102, China;
3.
School of Chemistry and Chemical Engineering, Shandong University, Jinan 250100, China
Received Date: 31 May 2024
Revised Date: 03 July 2024
Available Online: 23 December 2024

Abstract: This paper effectively employs anthropomorphism to narrate the discovery history, classification, mechanisms of action, adverse effects on human health, and guidelines for antibiotic use. It aims to engage readers in an enjoyable exploration of fundamental antibiotic knowledge.

Key words:

1. [1]
  Gould, K. J. Antimicrob. Chemother. 2016, 71 (3), 572.Gould, K. J. Antimicrob. Chemother. 2016, 71 (3), 572.
2. [2]
  Nelson, M. L.; Dinardo, A.; Hochberg, J.; Armelagos, G. J. Am. J. Phys. Anthropol. 2010, 143 (1), 151.Nelson, M. L.; Dinardo, A.; Hochberg, J.; Armelagos, G. J. Am. J. Phys. Anthropol. 2010, 143 (1), 151.
3. [3]
  Girolamo Fracastoro. [2024-05-01]. https://www.britannica.com/biography/Girolamo-FracastoroGirolamo Fracastoro. [2024-05-01]. https://www.britannica.com/biography/Girolamo-Fracastoro
4. [4]
  Tobyn, G. Int. J. Complement. Alt. Med. 2016, 3 (2), 45.Tobyn, G. Int. J. Complement. Alt. Med. 2016, 3 (2), 45.
5. [5]
  Boslaugh, S. E. The SAGE Encyclopedia of Pharmacology and Society; SAGE Publications: Los Angeles, CA, USA, 2015.Boslaugh, S. E. The SAGE Encyclopedia of Pharmacology and Society; SAGE Publications: Los Angeles, CA, USA, 2015.
6. [6]
  Agostino Bassi. [2024-05-01]. https://www.britannica.com/biography/Agostino-BassiAgostino Bassi. [2024-05-01]. https://www.britannica.com/biography/Agostino-Bassi
7. [7]
  Friedrich Gustav Jacob Henle. [2024-05-01]. https://www.britannica.com/biography/Friedrich-Gustav-Jacob-HenleFriedrich Gustav Jacob Henle. [2024-05-01]. https://www.britannica.com/biography/Friedrich-Gustav-Jacob-Henle
8. [8]
  Kadar, N. Am. J. Obstet. Gynecol. 2019, 220 (1), 26.Kadar, N. Am. J. Obstet. Gynecol. 2019, 220 (1), 26.
9. [9]
  Porter, J. R. Bacteriol. Rev. 1961, 25 (4), 389.Porter, J. R. Bacteriol. Rev. 1961, 25 (4), 389.
10. [10]
  Lakhtakia, R. Sultan Qaboos Univ. Med. J. 2014, 14 (1), e37.Lakhtakia, R. Sultan Qaboos Univ. Med. J. 2014, 14 (1), e37.
11. [11]
  李沛凌, 冯清, 袁红玲, 王芹. 大学化学, 2024, 39 (9), 122.
12. [12]
  Gerhard Domagk Facts. [2024-05-03]. https://www.nobelprize.org/prizes/medicine/1939/domagk/factsGerhard Domagk Facts. [2024-05-03]. https://www.nobelprize.org/prizes/medicine/1939/domagk/facts
13. [13]
  张帆. 生物学教学, 2008, 33 (7), 70.
14. [14]
  任婧, 李毓龙, 杨晓霖, 李乐平. 医学与哲学, 2020, 41 (18), 68.
15. [15]
  Abraham, E. P. Rev. Infect. Dis. 1979, 1 (1), 99.Abraham, E. P. Rev. Infect. Dis. 1979, 1 (1), 99.
16. [16]
  Bo, G. Clin. Microbiol. Infect. 2000, 6 (Suppl. 3), 6.Bo, G. Clin. Microbiol. Infect. 2000, 6 (Suppl. 3), 6.
17. [17]
  Ainsworth, G. C.; Brown, A. M.; Brownlee, G. Nature 1947, 159 (4060), 263.Ainsworth, G. C.; Brown, A. M.; Brownlee, G. Nature 1947, 159 (4060), 263.
18. [18]
  Ehrlich, J.; Bartz, Q. R.; Smith, R. M.; Joslyn, D. A.; Burkholder, P. R. Science 1947, 106 (2757), 417.Ehrlich, J.; Bartz, Q. R.; Smith, R. M.; Joslyn, D. A.; Burkholder, P. R. Science 1947, 106 (2757), 417.
19. [19]
  Nelson, M. L.; Levy, S. B. Ann. N. Y. Acad. Sci. 2011, 1241 (1), 17.Nelson, M. L.; Levy, S. B. Ann. N. Y. Acad. Sci. 2011, 1241 (1), 17.
20. [20]
  When Was Dr. Abelardo Aguilar Born? [2024-05-04]. https://whenwasborn.wiki/scientist/abelardo-aguilarWhen Was Dr. Abelardo Aguilar Born? [2024-05-04]. https://whenwasborn.wiki/scientist/abelardo-aguilar
21. [21]
  Stratton, C. W. Antimicrob. Infect. Dis. Newsl. 1998, 17 (12), 89.Stratton, C. W. Antimicrob. Infect. Dis. Newsl. 1998, 17 (12), 89.
22. [22]
  Emmerson, A. M.; Jones, A. M. J. Antimicrob. Chemother. 2003, 51 (Suppl. 1), 13.Emmerson, A. M.; Jones, A. M. J. Antimicrob. Chemother. 2003, 51 (Suppl. 1), 13.
23. [23]
  抗生素. [2024-05-07]. https://www.termonline.cn/search?searchText=%E6%8A%97%E7%94%9F%E7%B4%A0
24. [24]
  Antibiotic (adj.). [2024-05-04]. https://www.etymonline.com/word/antibioticAntibiotic (adj.). [2024-05-04]. https://www.etymonline.com/word/antibiotic
25. [25]
  Waksman, S. A. Mycologia 1947, 39 (5), 565.Waksman, S. A. Mycologia 1947, 39 (5), 565.
26. [26]
  唐宁馨. 抗生素, 1986, 11 (3), 289.
27. [27]
  樊德厚. 临床荟萃, 2002, 17 (4), 221.
28. [28]
  杨宝峰, 陈建国. 药理学. 第9版. 北京: 人民卫生出版社, 2018.
29. [29]
  唐琰, 丁雁, 刘嵘, 朱雄. 药学进展, 2012, 36 (10), 433.
30. [30]
  苹果酸奈诺沙星. [2024-05-08]. https://www.cphi.cn/news/show-wiki-170320.html
31. [31]
  Lima, L. M.; Silva, B.; Barbosa, G.; Barreiro, E. J. Eur. J. Med. Chem. 2020, 208, 112829.Lima, L. M.; Silva, B.; Barbosa, G.; Barreiro, E. J. Eur. J. Med. Chem. 2020, 208, 112829.
32. [32]
  楼洁, 胡晓, 梁延群, 朱怡铃, 音建华. 微生物学报, 2023, 63 (1), 106.
33. [33]
  苏思婷, 毛丹丹, 许师文, 俞晨洁, 袁振亚, 温洪宇. 微生物学通报, 2017, 44 (4), 902.
34. [34]
  Evans, M. E.; Feola, D. J.; Rapp, R. P. Ann. Pharmacother. 1999, 33 (9), 960.Evans, M. E.; Feola, D. J.; Rapp, R. P. Ann. Pharmacother. 1999, 33 (9), 960.
35. [35]
  Khondker, A.; Dhaliwal, A. K.; Saem, S.; Mahmood, A.; Fradin, C.; Moran-Mirabal, J.; Rheinstadter, M. C. Commun. Biol. 2019, 2, 67.Khondker, A.; Dhaliwal, A. K.; Saem, S.; Mahmood, A.; Fradin, C.; Moran-Mirabal, J.; Rheinstadter, M. C. Commun. Biol. 2019, 2, 67.
36. [36]
  Trimble, M. J.; Mlynarcik, P.; Kolar, M.; Hancock, R. E. Cold Spring Harb. Perspect. Med. 2016, 6 (10), a025288.Trimble, M. J.; Mlynarcik, P.; Kolar, M.; Hancock, R. E. Cold Spring Harb. Perspect. Med. 2016, 6 (10), a025288.
37. [37]
  孙吉峻, 陈前, 俞继榕, 赵全芹. 大学化学, 2023, 38 (7), 183.
38. [38]
  Aminov, R. I. Front. Microbiol. 2010, 1, 134.Aminov, R. I. Front. Microbiol. 2010, 1, 134.
39. [39]
  魏光, 叶英, 沈继录. 中国抗生素杂志, 2013, 38 (12), 886.
40. [40]
  Blaser, M. J. Science 2016, 352 (6285), 544.Blaser, M. J. Science 2016, 352 (6285), 544.
41. [41]
  张连爱, 刘运梅. 临床合理用药杂志, 2012, 5 (1), 82.
42. [42]
  Sorensen, R. U.; Jacobs, M. R.; Shurin, S. B. Pediatr. Infect. Dis. 1985, 4 (6), 701.Sorensen, R. U.; Jacobs, M. R.; Shurin, S. B. Pediatr. Infect. Dis. 1985, 4 (6), 701.
43. [43]
  李明阳, 李勇, 王昉彤, 崔芬芳. 中国抗生素杂志, 2014, 39 (2), 85.
44. [44]
  孟娟, 王良录. 中华临床免疫和变态反应杂志, 2016, 10 (4), 412.
45. [45]
  Wu, Q.; Zhang, X.; Du, J.; Hu, C. J. Pharm. Anal. 2022, 12 (3), 481.Wu, Q.; Zhang, X.; Du, J.; Hu, C. J. Pharm. Anal. 2022, 12 (3), 481.
46. [46]
  刘创基. 动物性食品中β-内酰胺类药物及其代谢物检测方法的研究[硕士学位论文]. 北京: 北京化工大学, 2010.
47. [47]
  张建民, 冯玲玲. 中国药房, 2006, 17 (20), 1572.
48. [48]
  刘群, 褚志杰. 临床合理用药, 2023, 16 (10), 166.
49. [49]
  Kasten, M. J. Mayo Clin. Proc. 1999, 74 (8), 825.Kasten, M. J. Mayo Clin. Proc. 1999, 74 (8), 825.
50. [50]
  Belum, G. R.; Belum, V. R.; Chaitanya, A. S.; Reddy, B. S. Travel Med. Infect. Dis. 2013, 11 (4), 231.Belum, G. R.; Belum, V. R.; Chaitanya, A. S.; Reddy, B. S. Travel Med. Infect. Dis. 2013, 11 (4), 231.
51. [51]
  刘海燕, 李婷婷, 杨亚彬. 药物不良反应杂志, 2015, 17 (2), 142.
52. [52]
  Sivagnanam, S.; Deleu, D. Crit. Care 2003, 7 (2), 119.Sivagnanam, S.; Deleu, D. Crit. Care 2003, 7 (2), 119.
53. [53]
  Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis. [2024-05-07]. https://medlineplus.gov/genetics/condition/stevens-johnson-syndrome-toxic-epidermal-necrolysisStevens-Johnson Syndrome/Toxic Epidermal Necrolysis. [2024-05-07]. https://medlineplus.gov/genetics/condition/stevens-johnson-syndrome-toxic-epidermal-necrolysis
54. [54]
  郑靖, 陈捷, 周仲荣. 机械工程学报, 2005, 41 (2), 158.
55. [55]
  Kragh, H. Bull. Hist. Chem. 2008, 33 (2), 82.Kragh, H. Bull. Hist. Chem. 2008, 33 (2), 82.
56. [56]
  赵宁民, 王睿, 梁蓓蓓, 蔡芸, 白楠, 林德峰, 周家军. 中国临床药理学杂志, 2011, 27 (1), 59.
57. [57]
  林志强, 陈婷婷, 傅新阳. 海峡药学, 2020, 32 (5), 83.
58. [58]
  吴让坤. 医学创新研究, 2007, 4 (24), 77.
59. [59]
  临床常用的给药途径有哪些. [2024-05-03]. https://www.nmpa.gov.cn/xxgk/kpzhsh/kpzhshyp/20171024171801835.html
60. [60]
  Mcmahon, S.; Jordan, S. F. Nat. Ecol. Evol. 2022, 6 (7), 832.Mcmahon, S.; Jordan, S. F. Nat. Ecol. Evol. 2022, 6 (7), 832.

扫一扫看文章

计量

PDF下载量: 0
文章访问数: 2
HTML全文浏览量: 0

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

抗生素军团告人类战友书

English

The Antibiotic Legion’s Manifesto to Human Allies

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

CCS Chemistry：颜徐州、鲍哲南：你的皮肤可能是一片SPMs

CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

CCS Chemistry：静电组装导向聚合- 聚电解质纳米凝胶量化制备新策略

CCS Chemistry：金黄色葡萄球菌醛基脱氢酶是如何识别特异性底物的？

计量

通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

抗生素军团告人类战友书

English

The Antibiotic Legion’s Manifesto to Human Allies

CCS Chemistry：嵌段共聚物自组装成 “三明治”二维有机材料，实现纳米级压力传感功能

CCS Chemistry：颜徐州、鲍哲南： 你的皮肤可能是一片SPMs

CCS Chemistry：工作高效不疲劳，只须让催化剂动起来

CCS Chemistry：静电组装导向聚合- 聚电解质纳米凝胶量化制备新策略

CCS Chemistry：金黄色葡萄球菌醛基脱氢酶是如何识别特异性底物的？

计量

文章相关

通讯作者: 陈斌, bchen63@163.com

中国化学会秘书处

CCS Chemistry：颜徐州、鲍哲南：你的皮肤可能是一片SPMs