Abstract: Taking the opportunity of the periodic evaluation of the National Experimental Teaching Demonstration Center, this article comprehensively summarizes the construction experience of the National Experimental Teaching Demonstration Center for Chemistry (Hunan University) from 2018 to 2022, including the establishment of management system and safety responsibility system, improvement of teaching conditions, construction of experimental teaching system, development of experimental courses and textbooks, achievements in talent cultivation, construction of teaching teams, and the leading role of demonstration. Additionally, the construction plan for the next stage is formulated from several aspects, such as the demonstration centerʼs carrying capacity, optimization of the experimental teaching system and development of experimental projects, digital construction of experiments, construction of teaching teams, and enhancement of its demonstration role. These construction strategies aim to better support the construction of national first-class undergraduate programs in chemistry, chemical engineering and applied chemistry at Hunan university, thereby promoting the cultivation of high-quality talents in chemistry and chemical engineering.