Citation: Lihui Jiang, Wanrong Dong, Hua Yang, Yongqing Xia, Hongjian Peng, Jun Yuan, Xiaoqian Hu, Zihan Zeng, Yingping Zou, Yiming Luo. Study on Extraction of p-Hydroxyacetophenone[J]. University Chemistry, ;2024, 39(11): 259-268. doi: 10.12461/PKU.DXHX202402056 shu

Study on Extraction of p-Hydroxyacetophenone

1.
College of Chemistry and Chemical Engineering, Central South University, Changsha 410083, China;
2.
College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China

Received Date: 26 February 2024
Revised Date: 21 May 2024

For the organic chemistry extraction experiments in some universities, the aqueous phenol solution (5 wt%) is normally extracted by ethyl acetate. However, phenol has moderate toxicity and corrosiveness, and it volatilizes easily during experimental operations such as extraction, organic phase drying and distillation solvent recovery. To promote greener laboratory practices and reduce the exposure to toxic compounds for both students and experimental mentors, as well as the environmental impact of phenol, the p-hydroxyacetophenone is selected to replace phenol for the lab course in the present work. The p-hydroxyacetophenone is a natural compound, which is widely used as additive in skincare cosmetics. The saturated aqueous solution of p-hydroxyacetophenone is prepared and extracted by the ethyl acetate or dichloromethane. The process of demulsify during the extraction process has been introduced and showed. Furthermore, the extraction efficiencies of these two solvents are compared.
- p-Hydroxyacetophenone,
- Extraction,
- Organic chemistry experiments
1. [1]
2. [2]
3. [3]
4. [4]
5. [5]
6. [6]
7. [7]
8. [8]
9. [9]
10. [10]
  Jang, M. S.; Park, H. Y.; Nam, K. H. Food Sci. Biotechnol. 2014, 23 (2), 555.
11. [11]
  Rocío, C.; Cecilia, C.; Marcela, A.; Mariana, B. S.; Susana, C. Food Chem. 2021, 335 (15), 127576.
12. [12]
13. [13]
14. [14]
15. [15]
16. [16]
17. [17]
18. [18]
19. [19]
20. [20]
21. [21]
22. [22]
23. [23]
24. [24]
25. [25]
26. [26]
27. [27]
28. [28]
29. [29]
30. [30]
31. [31]
32. [32]
33. [33]
34. [34]
35. [35]
36. [36]
37. [37]
38. [38]
39. [39]
40. [40]
41. [41]
1. [1]
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1.
沈阳化工大学材料科学与工程学院沈阳 110142