Citation: WANG Tao, MA Lamaocao, MA Hengchang. Research Progress on Cell Imaging Based on the Aggregation-induced Emission Fluorescent Probes[J]. Chinese Journal of Applied Chemistry, ;2018, 35(10): 1155-1165. doi: 10.11944/j.issn.1000-0518.2018.10.170461 shu

Research Progress on Cell Imaging Based on the Aggregation-induced Emission Fluorescent Probes

a.
Key Laboratory of Polymer Materials of Gansu Province; Key Laboratory of Macromolecule Materials, Ministry of Education, College of Chemistry and Chemical Engineering
b.
Shaw Library, Northwest Normal University, Lanzhou 730070, China

Corresponding author: MA Hengchang, mahczju@hotmail.com
Received Date: 21 December 2017
Revised Date: 8 April 2018
Accepted Date: 25 April 2018

Fund Project: National Natural Science Foundation of China 21764012Supported by the National Natural Science Foundation of China(No.21764012)

Figures(11)

Fluorescent probes as a major discovery in the field of chemical sensing at the end of the 20th century have the advantages of simple synthesis, high sensitivity, good selectivity, short response time and high visualization. The combination of the fluorescent group with the aggregation-induced emission(AIE) characteristics and the biocompatible polymer makes the fluorescent materials have the characteristics of low toxicity, good light stability and good biocompatibility. In molecular, ion detection and cell imaging technology it has been widely studied and applied. This review summarizes the fluorescence probes for cytoplasmic imaging, cell membrane imaging, mitochondrial imaging, lysosomal imaging, lipid droplet imaging, nuclear imaging, nuclear and mitochondrial dual-targeting imaging and the prospects for their application.
- fluorescence probe,
- chemical sensing,
- biological imaging,
- aggregation-induced emission
1. [1]
  Shimizu, Yoshinori. Light Emitting Device Having a Nitride Compound Semiconductor and a Phosphor Containing a Garnet Fluorescent Material: US. Patent, 5998925A[P]. 1999-12-07.
2. [2]
  Komoto, Satoshi. Semiconductor Light Emitting Device Including a Fluorescent Material: US Patent, 6340824A[P]. 2002-01-22.
3. [3]
  Xu X, Ray R, Gu Y. Electrophoretic Analysis and Purification of Fluorescent Single-walled Carbon Nanotube Fragments[J]. J Am Chem Soc, 2004,126(40):12736-12737. doi: 10.1021/ja040082h
4. [4]
  Shalon D, Smith S J, Brown P O. A DNA Microarray System for Analyzing Complex DNA Samples Using Two-color Fluorescent Probe Hybridization[J]. Genome Res, 1996,6(7):639-645. doi: 10.1101/gr.6.7.639
5. [5]
  Semisotnov G V, Rodionova N A, Razgulyaev O I. Study of the "Molten Globule" Intermediate State in Protein Folding by a Hydrophobic Fluorescent Probe[J]. Biopolymers, 1991,31(1):119-128. doi: 10.1002/(ISSN)1097-0282
6. [6]
  Betzig E, Patterson G H, Sougrat R. Imaging Intracellular Fluorescent Proteins at Nanometer Resolution[J]. Science, 2006,313(5793):1642-1645. doi: 10.1126/science.1127344
7. [7]
  Kinkhabwala A, Yu Z, Fan S. Large Single-molecule Fluorescence Enhancements Produced by a Bowtie Nanoantenna[J]. Nat Photonics, 2009,3(11):654-657. doi: 10.1038/nphoton.2009.187
8. [8]
  Eggeling C, Ringemann C. Direct Observation of the Nanoscale Dynamics of Membrane Lipids in a Living Cell[J]. Nature, 2009,457(7233):1159-1162. doi: 10.1038/nature07596
9. [9]
  Luo J, Xie Z, Lam J W Y. Aggregation-induced Emission of 1-Methyl-1, 2, 3, 4, 5-Pentaphenylsilole[J]. Chem Commun, 2001(18):1740-1741. doi: 10.1039/b105159h
10. [10]
  Hong Y, Lam J W Y, Tang B Z. Aggregation-induced Emission[J]. Chem Soc Rev, 2011,40(11):5361-5388. doi: 10.1039/c1cs15113d
11. [11]
  Hong Y, Lam J W Y, Tang B Z. Aggregation-induced Emission:Phenomenon, Mechanism and Applications[J]. Chem Commun, 2009(29):4332-4353. doi: 10.1039/b904665h
12. [12]
  Lakowicz J R. Topics in Fluorescence Spectroscopy Nonlinear and Two-Photon-Induced Fluorescence[J]. Springer Berlin, 2002,6(1):103-121.
13. [13]
  Li M, Hong Y, Wang Z. Fabrication of Chitosan Nanoparticles with Aggregation-Induced Emission Characteristics and Their Applications in Long-Term Live Cell Imaging[J]. Macromol Rapid Commun, 2013,34(9):767-771. doi: 10.1002/marc.v34.9
14. [14]
  Yan L, Zhang Y, Xu B. Fluorescent Nanoparticles Based on AIE Fluorogens for Bioimaging[J]. Nanoscale, 2016,8(5):2471-2487. doi: 10.1039/C5NR05051K
15. [15]
  Ding D, Mao D, Li K. Precise and Long-term Tracking of Adipose-derived Stem Cells and Their Regenerative Capacity via Superb Bright and Stable Organic Nanodots[J]. ACS Nano, 2014,8(12):12620-12631. doi: 10.1021/nn505554y
16. [16]
  Zhang X, Zhang X, Wang S. Surfactant Modification of Aggregation-induced Emission Material as Biocompatible Nanoparticles:Facile Preparation and Cell Imaging[J]. Nanoscale, 2013,5(1):147-150. doi: 10.1039/C2NR32698A
17. [17]
  Shao A, Xie Y, Zhu S. Far-Red and Near-IR AIE-Active Fluorescent Organic Nanoprobes with Enhanced Tumor-Targeting Efficacy:Shape-Specific Effects[J]. Angew Chem Int Ed, 2015,127(25):7383-7388. doi: 10.1002/ange.v127.25
18. [18]
  Lehn J M. Supramolecular Chemistry[M]. SHEN Xinghai, Trans. Beijing: Peking University Press, 2002: 6-7(in Chinese).
19. [19]
  Arai S, Lee S C, Chang Y T. A Molecular Fluorescent Probe for Targeted Visualization of Temperature at the Endoplasmic Reticulum[J]. Sci Rep-UK, 2014,46701.
20. [20]
  Zhang W, Liu W, Li P. Rapid-Response Fluorescent Probe for Hydrogen Peroxide in Living Cells Based on Increased Polarity of C B Bonds[J]. Anal Chem, 2015,87(19):9825-9828. doi: 10.1021/acs.analchem.5b02194
21. [21]
  Liu T, Liu X, Spring D R. Quantitatively Mapping Cellular Viscosity with Detailed Organelle Information via a Designed PET Fluorescent Probe[J]. Sci Rep-UK, 2014,45418.
22. [22]
  Cheng J, Ma X, Zhang Y. Optical Chemosensors Based on Transmetalation of Salen-based Schiff Base Complexes[J]. Inorg Chem, 2014,53(6):3210-3219. doi: 10.1021/ic5000815
23. [23]
  Zhou Y, Zhang J F, Yoon J. Fluorescence and Colorimetric Chemosensors for Fluoride-Ion Detection[J]. Chem Rev, 2014,114(10):5511-5571. doi: 10.1021/cr400352m
24. [24]
  Zhou X, Lee S, Xu Z. Recent Progress on the Development of Chemosensors for Gases[J]. Chem Rev, 2015,115(15):7944-8000. doi: 10.1021/cr500567r
25. [25]
  Goswami S, Das S, Aich K. A Chemodosimeter for the Ratiometric Detection of Hydrazine Based on Return of ESIPT and Its Application in Live-cell Imaging[J]. Org Lett, 2013,15(21):5412-5415. doi: 10.1021/ol4026759
26. [26]
  Yin J, Kwon Y, Kim D. Cyanine-based Fluorescent Probe for Highly Selective Detection of Glutathione in Cell Cultures and Live Mouse Tissues[J]. J Am Chem Soc, 2014,136(14):5351-5358. doi: 10.1021/ja412628z
27. [27]
  Liu B, Wang J, Zhang G. Flavone-based ESIPT Ratiometric Chemodosimeter for Detection of Cysteine in Living Cells[J]. ACS Appl Mater Interfaces, 2014,6(6):4402-4407. doi: 10.1021/am500102s
28. [28]
  Aigner D, Borisov S M, Fern ndez F J O. New Fluorescent pH Sensors Based on Covalently Linkable PET Rhodamines[J]. Talanta, 2012,99:194-201. doi: 10.1016/j.talanta.2012.05.039
29. [29]
  Park B W, Philippe B, Gustafsson T. Enhanced Crystallinity in Organic Inorganic Lead Halide Perovskites on Mesoporous TiO₂ via Disorder-Order Phase Transition[J]. Chem Mater, 2014,2(15):4466-4471.
30. [30]
  Liu Z, He W, Guo Z. Metal Coordination in Photoluminescent Sensing[J]. Chem Soc Rev, 2013,42(4):1568-1600. doi: 10.1039/c2cs35363f
31. [31]
  Xu Z, Yoon J, Spring D R. A Selective and Ratiometric Cu²⁺ Fluorescent Probe Based on Naphthalimide Excimer Monomer Switching[J]. Chem Commun, 2010,46(15):2563-2565. doi: 10.1039/c000441c
32. [32]
  Wu J, Liu W, Ge J. New Sensing Mechanisms for Design of Fluorescent Chemosensors Emerging in Recent Years[J]. Chem Soc Rev, 2011,40(7):3483-3495. doi: 10.1039/c0cs00224k
33. [33]
  Kim T I, Kang H J, Han G. A Highly Selective Fluorescent ESIPT Probe for the Dual Specificity Phosphatase MKP-6[J]. Chem Commun, 2009(39):5895-5897.
34. [34]
  Mei J, Hong Y, Lam J W Y. Aggregation-Induced Emission:The Whole is More Brilliant Than the Parts[J]. Adv Mater, 2014,26(31):5429-5479. doi: 10.1002/adma.201401356
35. [35]
  Chang Z F, Jing L M, Liu Y Y. Constructing Small Molecular AIE Luminophores Through a 2, 2-(2, 2-Diphenylethene-1, 1-diyl) Dithiophene Core and Peripheral Triphenylamine with Applications in Piezofluorochromism, Optical Waveguides, and Explosive Detection[J]. J Mater Chem C, 2016,4(36):8407-8415. doi: 10.1039/C6TC02395A
36. [36]
  Miyanari Y, Atsuzawa K, Usuda N. The Lipid Droplet is an Important Organelle for Hepatitis C Virus Production[J]. Nat Cell Biol, 2007,9(9):1089-1097. doi: 10.1038/ncb1631
37. [37]
  Berezney R. The Nuclear Matrix:A Heuristic Model for Investigating Genomic Organization and Function in the Cell Nucleus[J]. J Cell Biochem, 1991,47(2):109-123. doi: 10.1002/(ISSN)1097-4644
38. [38]
  Vendrell M, Zhai D, Er J C. Combinatorial Strategies in Fluorescent Probe Development[J]. Chem Rev, 2012,112(8):4391-4420. doi: 10.1021/cr200355j
39. [39]
  Xu W, Zeng Z, Jiang J H. Discerning the Chemistry in Individual Organelles with Small-Molecule Fluorescent Probes[J]. Angew Chem Int Ed, 2016,55(44):13658-13699. doi: 10.1002/anie.201510721
40. [40]
  Li Y, Shao A, Wang Y. Tumor Bioimaging:Morphology-Tailoring of a Red AIEgen from Microsized Rods to Nanospheres for Tumor-Targeted Bioimaging[J]. Adv Mater, 2016,28(16):3224-3224. doi: 10.1002/adma.201670113
41. [41]
  Li Y, Shao A, Wang Y. Morphology-Tailoring of a Red AIEgen from Microsized Rods to Nanospheres for Tumor-Targeted Bioimaging[J]. Adv Mater, 2016,28(16):3187-3193. doi: 10.1002/adma.201504782
42. [42]
  Umezawa K, Yoshida M, Kamiya J M. Rational Design of Reversible Fluorescent Probes for Live-cell Imaging and Quantification of Fast Glutathione Dynamics[J]. Nat Chem, 2017,9(3):279-286. doi: 10.1038/nchem.2648
43. [43]
  Ma H, Yang M, Zhang C. Aggregation-induced Emission(AIE)-active Fluorescent Probes with Multiple Binding Sites Toward ATP Sensing and Live Cell Imaging[J]. J Mater Chem B, 2017,5(43):8525-8531. doi: 10.1039/C7TB02399E
44. [44]
  Pedram P, Mahani M, Torkzadeh-Mahani M. Cadmium Sulfide Quantum Dots Modified with the Human Transferrin Protein Siderophiline for Targeted Imaging of Breast Cancer Cells[J]. Microchim Acta, 2016,183(1):67-71. doi: 10.1007/s00604-015-1593-6
45. [45]
  Sun L, Ding J, Xing W. Novel Strategy for Preparing Dual-modality Optical/PET Imaging Probes via Photo-click Chemistry[J]. Biol Chem, 2016,27(5):1200-1204.
46. [46]
  Domaille D W, Que E L, Chang C J. Synthetic Fluorescent Sensors for Studying the Cell Biology of Metals[J]. Nat Chem Biol, 2008,4(3):168-175. doi: 10.1038/nchembio.69
47. [47]
  Liang J, Li K, Liu B. Visual Sensing with Conjugated Polyelectrolytes[J]. Chem Soc, 2013,4(4):1377-1394.
48. [48]
  Ma H, Qi C, Cheng C. AIE-active Tetraphenylethylene Cross-linked N-Isopropylacrylamide Polymer:A Long-term Fluorescent Cellular Tracker[J]. ACS Appl Mater Interfaces, 2016,8(13):8341-8348. doi: 10.1021/acsami.5b11091
49. [49]
  Wang B, Zhu C, Liu L. Synthesis of a New Conjugated Polymer for Cell Membrane Imaging by Using an Intracellular Targeting Strategy[J]. Polym Chem-UK, 2013,4(20):5212-5215. doi: 10.1039/c3py00097d
50. [50]
  Zhang C, Jin S, Yang K. Cell Membrane Tracker Based on Restriction of Intramolecular Rotation[J]. ACS Appl Mater Interfaces, 2014,6(12):8971-8975. doi: 10.1021/am5025897
51. [51]
  Jouaville L S, Pinton P, Bastianutto C. Regulation of Mitochondrial ATP Synthesis by Calcium:Evidence for a Long-term Metabolic Priming[J]. PNAS, 1999,96(24):13807-13812. doi: 10.1073/pnas.96.24.13807
52. [52]
  Suen D F, Norris K L, Youle R J. Mitochondrial Dynamics and Apoptosis[J]. Gene Dev, 2008,22(12):1577-1590. doi: 10.1101/gad.1658508
53. [53]
  Leung C W T, Hong Y, Chen S. A Photostable AIE Luminogen for Specific Mitochondrial Imaging and Tracking[J]. J Am Chem Soc, 2013,135(1):62-65. doi: 10.1021/ja310324q
54. [54]
  Van Meel E, Klumperman J. Imaging and Imagination:Understanding the Endo-lysosomal System[J]. Histo Chem Cell Biol, 2008,129(3):253-266. doi: 10.1007/s00418-008-0384-0
55. [55]
  Gao M, Hu Q, Feng G. A Fluorescent Light-up Probe with "AIE+ ESIPT" Characteristics for Specific Detection of Lyssomal Esterase[J]. J Mater Chem B, 2014,2(22):3438-3442. doi: 10.1039/C4TB00345D
56. [56]
  Martin S, Parton R G. Opinion:Lipid Droplets:A Unified View of a Dynamic Organelle[J]. Nat Rev Mol Cell Biol, 2006,7(5):373-378. doi: 10.1038/nrm1912
57. [57]
  Alberti K G M M, Zimmet P, Shaw J. Metabolic Syndrome-A New World-wide Definition. A Consensus Statement from the International Diabetes Federation[J]. Diabetic Med, 2006,23(5):469-480. doi: 10.1111/dme.2006.23.issue-5
58. [58]
  Wang Z, Gui C, Zhao E. Specific Fluorescence Probes for Lipid Droplets Based on Simple AIEgens[J]. ACS Appl Mater Interfaces, 2016,8(16):10193-10200. doi: 10.1021/acsami.6b01282
59. [59]
  Kobayashi H, Ogawa M, Alford R. New Strategies for Fluorescent Probe Design in Medical Diagnostic Imaging[J]. Chem Rev, 2009,110(5):2620-2640.
60. [60]
  Horobin R W, Stockert J C, Rashid-Doubell F. Fluorescent Cationic Probes for Nuclei of Living Cells:Why Are They Selective? A Quantitative Structure-Activity Relations Analysis[J]. Histochem Cell Biol, 2006,126(2):165-175. doi: 10.1007/s00418-006-0156-7
61. [61]
  Collas P, Aleström P. Rapid Targeting of Plasmid DNA to Zebrafish Embryo Nuclei by the Nuclear Localization Signal of SV 40T Antigen[J]. Mol Mar Biol Biotechnol, 1997,6(1):48-58.
62. [62]
  Wade W, Grabow , Luc J. RNA Self-Assembly and RNA Nanotechnology[J]. Acc Chem Res, 2014,47:1871-1880. doi: 10.1021/ar500076k
63. [63]
  Chris Y Y, Kwok R T K, Tang B Z. A Photostable AIEgen for Nucleolus and Mitochondria Imaging with Organelle-specific Emission[J]. J Mater Chem B, 2016,4(15):2614-2619. doi: 10.1039/C6TB00319B
64. [64]
  Ma H, Yang M, Zhang C. Aggregation-induced Emission(AIE)-active Fluorescent Probes with Multiple Binding Sites Toward ATP Sensing and Live Cell Imaging[J]. J Mater Chem B, 2017,5(43):8525-8531. doi: 10.1039/C7TB02399E
65. [65]
  Haugland R P. Handbook of Fluorescent Probes and Research Products[M]. 9th Edn. Eugene OR: Molecular Probes, USA, 2002.
66. [66]
  Giepmans B N, Adams S R, Ellisman M H. The Fluorescent Toolbox for Assessing Protein Location and Function[J]. Science, 2006,312(5771):217-224. doi: 10.1126/science.1124618
67. [67]
  Ashkenazi A. Targeting Death and Decoy Receptors of the Tumour-necrosis Factor Superfamily[J]. Nat Rev Cancer, 2002,2(6):420-430. doi: 10.1038/nrc821
68. [68]
  Ma H, Yang Z, Cao H. One Bioprobe:A Fluorescent and AIE-active Macromolecule; Two Targets:Nucleolus and Mitochondria with Long Term Tracking[J]. J Mater Chem B, 2017,5(4):655-660. doi: 10.1039/C6TB02844F
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