Citation: WANG Tao, MA Lamaocao, MA Hengchang. Research Progress on Cell Imaging Based on the Aggregation-induced Emission Fluorescent Probes[J]. Chinese Journal of Applied Chemistry, ;2018, 35(10): 1155-1165. doi: 10.11944/j.issn.1000-0518.2018.10.170461 shu

Research Progress on Cell Imaging Based on the Aggregation-induced Emission Fluorescent Probes

a.
Key Laboratory of Polymer Materials of Gansu Province; Key Laboratory of Macromolecule Materials, Ministry of Education, College of Chemistry and Chemical Engineering
b.
Shaw Library, Northwest Normal University, Lanzhou 730070, China

Corresponding author: MA Hengchang, mahczju@hotmail.com
Received Date: 21 December 2017
Revised Date: 8 April 2018
Accepted Date: 25 April 2018

Fund Project: National Natural Science Foundation of China 21764012Supported by the National Natural Science Foundation of China(No.21764012)

Figures(11)

Fluorescent probes as a major discovery in the field of chemical sensing at the end of the 20th century have the advantages of simple synthesis, high sensitivity, good selectivity, short response time and high visualization. The combination of the fluorescent group with the aggregation-induced emission(AIE) characteristics and the biocompatible polymer makes the fluorescent materials have the characteristics of low toxicity, good light stability and good biocompatibility. In molecular, ion detection and cell imaging technology it has been widely studied and applied. This review summarizes the fluorescence probes for cytoplasmic imaging, cell membrane imaging, mitochondrial imaging, lysosomal imaging, lipid droplet imaging, nuclear imaging, nuclear and mitochondrial dual-targeting imaging and the prospects for their application.
- fluorescence probe,
- chemical sensing,
- biological imaging,
- aggregation-induced emission
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