Citation: SHI Yun, LI Mengsheng, DAN Yanni. Peroxidation of Benzoylimidazole[J]. Chinese Journal of Applied Chemistry, ;2018, 35(5): 511-517. doi: 10.11944/j.issn.1000-0518.2018.05.170162 shu

Peroxidation of Benzoylimidazole

College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, China

Corresponding author: SHI Yun, shiyun@lzu.edu.cn
Received Date: 17 May 2017
Revised Date: 8 August 2017
Accepted Date: 6 September 2017

Fund Project: the National Natural Science Foundation of China 21101663the Gansu Province Youth Science and Technology Fund Project 1107RJYA080Supported by the National Natural Science Foundation of China(No.21101663), the Gansu Province Youth Science and Technology Fund Project(No.1107RJYA080)

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In this paper, the experimental methods for the synthesis of t-butyl peroxide compounds were discussed, in which benzoyl imidazole and t-butyl hydroperoxide(TBHP) were used as reactants, 1, 8-diazabicycloundec-7-ene(DBU) was used as the catalyst and acetonitrile(CH₃CN) was used as the reaction solvent. The effect of catalysts and their dosage, raw material ratios, solvents and temperature on the yield were investigated. A total of 25 target products were obtained under the optimum conditions with yields of 45%~99%. The molecular structures of the products were analyzed by nuclear magnetic resonance spectroscopy(¹H NMR and ¹³C NMR) and mass spectrometry. The method has the advantage of easily available material, easy operation, mild reaction conditions and a wide range of functional group tolerance, and has provided a new idea for the synthesis of t-butyl peroxide compounds.
- benzoylimidazole,
- t-butyl hydroperoxide,
- diazabicycloundec-ene catalyst,
- t-butyl peroxide compounds
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