Citation: ZHANG Xing-Lei, ZHANG Hua, WANG Xin-Chen, HUANG Ke-Ke, WANG Dan, CHEN Huan-Wen. Advances in Ambient Ionization for Mass Spectrometry[J]. Chinese Journal of Analytical Chemistry, ;2018, 46(11): 1703-1713. doi: 10.11895/j.issn.0253-3820.181509 shu

Advances in Ambient Ionization for Mass Spectrometry

¹ East China University of Technology, Jiangxi Key Laboratory for Mass Spectrometry and Instrumentation, Nanchang 330013, China;
² State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, College of Chemistry, Jilin University, Changchun 130012, China

Received Date: 4 August 2018
Revised Date: 30 August 2018

Fund Project: This work was supported by the National Natural Science Foundation of China (Nos. 21727812, 21675021), the Science and Technology Planning Project at the Ministry of Science and Technology of Jiangxi Province (No. 2010BNB00900) and the Jiangxi Key Laboratory for Mass Spectrometry and Instrumentation Open Foundation (No. JXMS201612).

Over the past decade, ambient mass spectrometry (AMS) has become an important scientific research tool and is widely used in various important fields such as pharmaceuticals, food, environment, public safety, clinic diagnosis and so on. Ambient ionization technology, as the key for AMS analysis, allows the direct sampling/ionization of analytes from raw practical samples without any sample pretreatment, and has greatly improved the analytical efficiency. At present, nearly 100 kinds of different ambient ionization technologies have been developed for the study of complex solid, gaseous, liquid, and even viscous samples. Herein, the ambient ionization methods were introduced by the aspect of energy and charge transfer process, and the new ambient ionization devices developed in the last 5 years were briefly summarized and discussed. Furthermore, the advantages and disadvantages of ambient ionization technology, and the possible development direction of atmospheric ionization technology in the future were prospected.
- Mass spectrometry,
- Ambient ionization,
- Direct analysis,
- Energy and charge transfer process,
- Review
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