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Citation: WANG Kun, HUANG Xin-Wen, LIN Kun-De. Non-target Screening of Halogenated Organic Compounds Using Liquid Chromatography-Tandem Mass Spectrometry Precursor Ion Scan[J]. Chinese Journal of Analytical Chemistry, ;2018, 46(11): 1821-1828. doi: 10.11895/j.issn.0253-3820.181364 shu

Non-target Screening of Halogenated Organic Compounds Using Liquid Chromatography-Tandem Mass Spectrometry Precursor Ion Scan

¹ The Fujian Provincial Key Laboratory for Coastal Ecology and Environmental Studies, Center for Marine Environmental Chemistry and Toxicology, College of the Environment and Ecology, Xiamen University, Xiamen 361102, China;
² College of Environment, Zhejiang University of Technology, Hangzhou 310014, China

Received Date: 31 May 2018
Revised Date: 14 August 2018

Fund Project: This work was supported by the National Natural Science Foundation of China (No. 21477115, 21876142).

A new analytical method based on liquid chromatography-tandem mass spectrometry (LC-MS/MS) precursor ion scan (PIS) was developed for the non-target screening of halogenated organic compounds (HOCs). Briefly, fragmented halogen ions from the precursor of HOCs could pass Q3 channels fixing at m/z 35, 37, 79, 81 and 127, and the corresponding precursors were simultaneously recorded in Q1. Therefore, the halogenated species and molecular ions of HOCs could be inferred from the selection of Q3 and Q1. Results showed that PIS had a higher sensitivity to HOCs when the collision energy in Q2 was set at 50 eV. Bernoulli experiment models were used to calculate theoretical isotopic abundances of HOCs. This method was successfully applied to the screening of HOCs in laboratory reaction samples and seawater. This work suggested that PIS was potentially an effective tool for the non-target screening of HOCs in various environmental matrices.
- Liquid chromatography-tandem mass spectrometry,
- Precursor ion scan,
- Halogenated organic compounds,
- Isotopic abundance
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2. [2]
3. [3]
4. [4]
5. [5]
6. [6]
7. [7]
8. [8]
9. [9]
10. [10]
11. [11]
12. [12]
13. [13]
14. [14]
15. [15]
16. [16]
17. [17]
18. [18]
19. [19]
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