Citation: ZANG Xiao-Qian, LI Zhe-Yu, ZHANG Xiao-Yan, JIANG Lei, REN Nan-Qi, SUN Kai. Advance in Bacteria Chemotaxis on Microfluidic Devices[J]. Chinese Journal of Analytical Chemistry, ;2017, 45(11): 1734-1744. doi: 10.11895/j.issn.0253-3820.170259 shu

Advance in Bacteria Chemotaxis on Microfluidic Devices

1.
State Key Laboratory of Urban Water Resource and Environment, Harbin Institute of Technology, Harbin 150090, China;
2.
Technical Institute of Physics and Chemistry, Chinese Academy of Sciences, Beijing 100101, China

Received Date: 24 April 2017
Revised Date: 18 May 2017

Fund Project: This work was supported by the National Natural Science Foundation of China (No.61674046).

Chemotaxis is the response ability of motile cells to chemicals gradients in environment and the migration toward higher concentration of chemoattractant or lower concentration of repellent. This mechanism is a basic nature of microorganisms to adapt to the environmental changes. The research of microbial chemotaxis is of great significance in utilizing bacteria to solve environment problems, control the pathogen infection, and develop microbial industrial projects. Microfluidic devices can realize qualitatively and quantitatively detect of bacterial chemotaxis. In comparison with traditional detect methods, microfluidic assay has an accurate control over bacterial microenvironment, with a higher sensitivity. In the past few years, bacterial chemotaxis study based on microfluidic assay was developed rapidly. In this paper, the microfluidic chemotaxis detectors that appeared in recent years were introduced from the aspect of chip structure, working principle and their applications. Finally, we provided insights into the challenges of bacterial chemotaxis and provided future perspectives.
- Macrofluidics,
- Bacteria,
- Chemotaxis,
- Microenvironment,
- Review
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沈阳化工大学材料科学与工程学院沈阳 110142