Citation: LI Jian-Wen, WEI Shou-Lian, Chen Na-Na. A Ribavirin Potentiometric Sensor Based on Molecularly Imprinted Polymers Doped with Graphene Oxide Film[J]. Chinese Journal of Analytical Chemistry, ;2017, 45(7): 1031-1037. doi: 10.11895/j.issn.0253-3820.170063 shu

A Ribavirin Potentiometric Sensor Based on Molecularly Imprinted Polymers Doped with Graphene Oxide Film

1.
Guangdong Food and Drug Vocational College, Guangzhou 510620, China;
2.
Faculty of Chemistry and Chemical Engineering, Zhaoqing University, Zhaoqing 526061, China

Received Date: 25 January 2017
Revised Date: 21 April 2017

Molecularly imprinted polymer (MIP) was synthesized by precipitation polymerization using ribavirin as the template molecule and methacrylic acid as the functional monomer. The sensitive film of ribavirin electrode was constructed by molecularly imprinted polymer doped with graphene oxide as the ionophore, poly(vinylchloride) (PVC) as matrix and dioctyl sebacate for plasticizer. The results showed that the best performance of the electrode was obtained when the sensitive film compositions were 100.8 mg of MIP, 14.7 mg of GO, 450.8 mg of PVC and 901.6 mg of dioctyl sebacate, and the inner filling solution composition was 0.1 mol/L NaCl + 0.05 mol/L NaAc-0.05 mol/L HAc + 1.0×10^-5 mol/L ribavirin solution. The electrode showed a near-Nernstian slope of 45.565 mV/decade for ribavirin over the range of 1.0×10⁶-1.0×10^-4 mol/L and a detection limit of 1.0×10^-7 mol/L. The electrode could be used in the pH range of 3 to 5 with response time of less than 3 min. The developed electrode exhibited high selectivity for ribavirin and was successfully applied to the determination of ribavirin in feed and injection with recoveries of 90%-110% and RSD of 3.0%-7.9%.
- Ribavirin,
- Imprinted polymer,
- Graphene oxide,
- Potentiometric sensor,
- Feed
1. [1]
2. [2]
3. [3]
4. [4]
5. [5]
6. [6]
7. [7]
8. [8]
9. [9]
10. [10]
11. [11]
12. [12]
13. [13]
14. [14]
15. [15]
16. [16]
17. [17]
18. [18]
19. [19]
20. [20]
21. [21]
22. [22]
23. [23]
24. [24]
25. [25]
1. [1]
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1.
沈阳化工大学材料科学与工程学院沈阳 110142