Citation: SUN Bo-Lu, GOU Yu-Qiang, MA Yu-Ling, ZHENG Xiao-Ping, HU Fang-Di. Electrochemical Sensor for Assessment of Antioxidant Activities of Ferulic Acid and Extract in Angelica Sinensis Based on DNA/Nafion- Poly(diallyldimethylammonium chloride) Functionalized Graphene[J]. Chinese Journal of Analytical Chemistry, ;2016, 44(10): 1575-1583. doi: 10.11895/j.issn.0253-3820.160172 shu

Electrochemical Sensor for Assessment of Antioxidant Activities of Ferulic Acid and Extract in Angelica Sinensis Based on DNA/Nafion- Poly(diallyldimethylammonium chloride) Functionalized Graphene

1.
School of Pharmacy, Lanzhou University, Lanzhou 730000, China;
2.
Lanzhou Military Command Center for Disease Prevention and Control, Lanzhou 730050, China

Received Date: 9 March 2016
Revised Date: 3 August 2016

Figures(7)

A simple electrochemical sensor was constituted based on the glassy carbon electrode (GCE) surface modified with nafion-poly (diallyldimethylammonium chloride) functionalized graphene sheets (NA-PDDA-G) composite film and herring sperm double-stranded DNA for direct detection of DNA damage in vitro and evaluation of the antioxidant properties of ferulic acid (FA) and the aqueous extracts in Angelica Sinensis (EAS). Scanning electron microscopy (SEM) was used to characterize the morphologies of the fabricated sensor, while cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) were used to characterize the electrochemical performances of the modified electrode. Ru(NH₃)₆³⁺ was used as an electroactive indicator to monitor DNA damage induced by hydroxyl radical (·OH) with square wave voltammetry (SWV). The fabricated sensor showed the greatest degree of DNA oxidation damage occurred under the conditions of 30-min incubation in Fenton reagent containing 1.0 mmol/L FeSO₄ and 5.0 mmol/L H₂O₂ at pH 7.0. The antioxidant activity of extract in Angelica Sinensis (EAS) was stronger than that of FA, while they were all weaker than that of ascorbic acid (AA). The proposed sensor not only exhibited excellent stability and reproducibility, but would be a simple and novel method for assessment of antioxidant properties of medicinal herb components.
- Electrochemical sensor,
- Square wave voltammetry,
- Deoxyribonucleic acid,
- Ferulic acid,
- Aqueous extracts in Angelica Sinensis,
- Antioxidant property
1. [1]
2. [2]
3. [3]
4. [4]
5. [5]
6. [6]
7. [7]
8. [8]
9. [9]
10. [10]
11. [11]
12. [12]
13. [13]
14. [14]
15. [15]
16. [16]
17. [17]
18. [18]
19. [19]
20. [20]
21. [21]
22. [22]
23. [23]
24. [24]
25. [25]
26. [26]
27. [27]
28. [28]
29. [29]
30. [30]
31. [31]
32. [32]
33. [33]
34. [34]
35. [35]
1. [1]
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沈阳化工大学材料科学与工程学院沈阳 110142