Citation: LIU Rong, LONG Li-Ping, LEI Cun-Xi, Wu Zhao-Yang, LIU Yu, LI Si-Jia. Fabrication and Application of a Molecularly Imprinted Sensor for Morin Detection[J]. Chinese Journal of Analytical Chemistry, ;2016, 44(3): 385-390. doi: 10.11895/j.issn.0253-3820.150761 shu

Fabrication and Application of a Molecularly Imprinted Sensor for Morin Detection

LIU Rong ^1,2 ,
LONG Li-Ping ^1,, ,
LEI Cun-Xi ¹ ,
Wu Zhao-Yang ² ,
LIU Yu ¹ ,
LI Si-Jia ¹

1.
¹ College of Chemistry & Environmental Engineering, Hunan City University, Yiyang 413000, China;
2.
² State Key Laboratory of Chemo/Biosensing and Chemometrics, Hunan University, Changsha 410082, China

Corresponding author: LONG Li-Ping,
Received Date: 26 September 2015
Available Online: 27 November 2015
Fund Project: 本文系湖南省教育厅高校科研一般项目(No.15C0244) (No.15C0244)国家自然科学基金项目(No.21545003) (No.21545003)湖南省自然科学基金项目(No.2015JJ2023) (No.2015JJ2023)湖南省高校科技创新团队支持计划项目(No.2014)207号)资助 (No.2014)207号)

Based on the intermolecular interaction, a molecularly imprinted polymer electrochemical sensor with specific identification of cavity on gold electrode surface was proposed with o-aminophenol as functional monomers and morin as template molecule. The performance and effect of MIP were investigated by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). Factors affecting the properties of sensor, such as polymeric membrane ratio, scanning cycles, elution time and adsorption time were investigated. Substances which had a similar structure to morin was used to compared the selective response. The result showed that the sensor had a good selectivity to morin. Under the optimized experiment conditions, the current response of the imprinted sensor was linear to the concentration of morin in the range of 0.05-1.7 μmol/L with linear equation as follows: I(μA)= 1.0800lgc(mol/L)+ 9.3599(R=0.9934), and the detection limit of 0.1 μmol/L. The sensor was used to determine the content of morin in black tea samples, and the recoveries of standard addition were between 104.0% and 108.0%.
- Molecularly imprinted,
- Morin,
- Electrochemical sensor,
- Electropolymerization
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