Citation: LIU Rong, LONG Li-Ping, LEI Cun-Xi, Wu Zhao-Yang, LIU Yu, LI Si-Jia. Fabrication and Application of a Molecularly Imprinted Sensor for Morin Detection[J]. Chinese Journal of Analytical Chemistry, ;2016, 44(3): 385-390. doi: 10.11895/j.issn.0253-3820.150761 shu

Fabrication and Application of a Molecularly Imprinted Sensor for Morin Detection

LIU Rong ^1,2 ,
LONG Li-Ping ^1,, ,
LEI Cun-Xi ¹ ,
Wu Zhao-Yang ² ,
LIU Yu ¹ ,
LI Si-Jia ¹

1.
¹ College of Chemistry & Environmental Engineering, Hunan City University, Yiyang 413000, China;
2.
² State Key Laboratory of Chemo/Biosensing and Chemometrics, Hunan University, Changsha 410082, China

Corresponding author: LONG Li-Ping,
Received Date: 26 September 2015
Available Online: 27 November 2015
Fund Project: 本文系湖南省教育厅高校科研一般项目(No.15C0244) (No.15C0244)国家自然科学基金项目(No.21545003) (No.21545003)湖南省自然科学基金项目(No.2015JJ2023) (No.2015JJ2023)湖南省高校科技创新团队支持计划项目(No.2014)207号)资助 (No.2014)207号)

Based on the intermolecular interaction, a molecularly imprinted polymer electrochemical sensor with specific identification of cavity on gold electrode surface was proposed with o-aminophenol as functional monomers and morin as template molecule. The performance and effect of MIP were investigated by cyclic voltammetry (CV) and differential pulse voltammetry (DPV). Factors affecting the properties of sensor, such as polymeric membrane ratio, scanning cycles, elution time and adsorption time were investigated. Substances which had a similar structure to morin was used to compared the selective response. The result showed that the sensor had a good selectivity to morin. Under the optimized experiment conditions, the current response of the imprinted sensor was linear to the concentration of morin in the range of 0.05-1.7 μmol/L with linear equation as follows: I(μA)= 1.0800lgc(mol/L)+ 9.3599(R=0.9934), and the detection limit of 0.1 μmol/L. The sensor was used to determine the content of morin in black tea samples, and the recoveries of standard addition were between 104.0% and 108.0%.
- Molecularly imprinted,
- Morin,
- Electrochemical sensor,
- Electropolymerization
1. [1]
  1 WU Xiang-An. Anhua Black Tea. Changsha: Hunan Publishing House of Science and Technology. 2008: 16 伍湘安. 安化黑茶. 长沙:湖南科学技术出版社, 2008: 16
2. [2]
  2 Gopal J V. Pharm J., 2013, 5(3): 123-126
3. [3]
  3 WANG Xiu-Lin. Metaluragicall Anaysis, 1992, 12(3): 36-40王修林. 治金分析, 1992, 12(3): 36-40
4. [4]
  4 Naso L G, Lezama L, Rojo T, Etcheverry S B, Valcarcel M, Roura M, Salado C, Ferrer E G, Williams P A M. Chemico-Biological Interactions, 2013, 206(2): 289-301
5. [5]
  5 JIA Xiao-Yan, LI Nian-Bing, LUO Hong-Qun. Chinese J. Pharm. Anal., 2010, 30(2): 266-270贾小燕, 李念兵, 罗红群. 药物分析杂志, 2010, 30(2): 266-270
6. [6]
  6 YANG Li, LIU De-Long, WEI Yong-Ju. Journal of Instrumental Analysis, 2014, 33(9): 1038-1043杨莉, 刘德龙, 魏永巨. 分析测试学报, 2014, 33(9): 1038-1043
7. [7]
  7 ZHANG Jun-Cai. Journal of Instrumental Analysis, 2006, 25(1): 112-114张君才. 分析测试学报, 2006, 25(1): 112-114
8. [8]
  8 HUANG Fei, ZENG Bai-Zhao, ZHAO Fa-Qiong, YANG Yu-Xia. Journal of Analytical Science, 2004, 20(2): 125-128黄菲, 曾百肇, 赵发琼,杨玉霞. 分析科学学报, 2004, 20(2): 125-128
9. [9]
  9 Liu J, Li Y, Wu X, Wang W, Ye B. Sensor Lett., 2013, 11(9): 1579-1585
10. [10]
  10 WANG Chun-Qiong, BAI Hui-Ping, CHEN Jing, CAO Qiu-E. Chinese J. Anal. Chem., 2014, 42(6): 842-846王春琼, 白慧萍, 陈瑾, 曹秋娥. 分析化学, 2014, 42(6): 842-846
11. [11]
  11 GAO Yang, WANG Wei, LIU Ying-Zi, TAO Qiang,WAN Xue, ZHANG Juan-Kun. Chinese J. Anal. Chem., 2015, 43(2): 212-217高杨, 王伟, 刘英姿, 陶强, 万雪, 张娟琨. 分析化学, 2015, 43(2): 212-217
12. [12]
  12 Behzad R, Najmeh M, Ali A. E. Anal. Method. 2011, 11(3): 2510-2516
13. [13]
  13 Sun S, Zhang M Q, Li Y J, He X W. Sensors, 2013, 13 (5): 5493-5506
14. [14]
  14 LIU Rong, ZHONG Tong-Sheng, LONG Li-Ping, YING Zhi-Fang, CAO Wei. Chinese J. Appl. Chem., 2013, 30(11): 1361-1365刘蓉, 钟桐生, 龙立平, 尹志芳, 曹伟. 应用化学, 2013, 30(11): 1361-1365
15. [15]
  15 WU Zhao-Yang, LUO Fei-Fei, LUAN Cong-Lin, JIANG Xiao-Hua, MEI Qiong-Zhi. Journal of Hunan University (Natural Sciences), 2013, 40(10): 79-82吴朝阳, 罗飞飞, 栾崇林, 蒋晓华, 梅琼之. 湖南大学学报(自然科学版) 2013, 40(10): 79-82
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