Citation: Tingting XU, Wenjing ZHANG, Yongbo SONG. Research advances of atomic precision coinage metal nanoclusters in tumor therapy[J]. Chinese Journal of Inorganic Chemistry, ;2024, 40(12): 2275-2285. doi: 10.11862/CJIC.20240229 shu

Research advances of atomic precision coinage metal nanoclusters in tumor therapy

School of Biomedical Engineering, Anhui Medical University, Hefei 230032, China

Corresponding author: Yongbo SONG, ybsong860@ahmu.edu.cn
Received Date: 20 June 2024
Revised Date: 24 October 2024

Figures(7)

Malignant tumors are one of the most serious threats to human health, and it has been a wildly discussed topic to establish efficient and accurate tumor treatment techniques. With the rapid development of nanomedicine technology, nanomaterial-mediated tumor treatment techniques have attracted more attention due to their low invasiveness, high specificity, and good therapeutic effects. As a new member of the nanomaterial family, atomically precise coinage metal nanoclusters show great potential in tumor treatment due to their excellent biocompatibility, surface modifiability, good optical properties, and efficient catalytic activity (generation of reactive oxygen species). This review mainly discusses the progress of research on atomically precise coinage metal nanoclusters in tumor treatment. Their antitumor mechanism is detailed in different therapies (radiation therapy, photothermal therapy, photodynamic therapy, chemodynamic therapy, drug delivery, and multimodal combination therapy). Moreover, the current challenges and prospects of metal nanoclusters in antitumors are summarized.
- atomically precise,
- coinage metal nanocluster,
- tumor,
- therapy
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沈阳化工大学材料科学与工程学院沈阳 110142