Citation: Changqing MIAO, Fengjiao CHEN, Wenyu LI, Shujie WEI, Yuqing YAO, Keyi WANG, Ni WANG, Xiaoyan XIN, Ming FANG. Crystal structures, DNA action, and antibacterial activities of three tetranuclear lanthanide-based complexes[J]. Chinese Journal of Inorganic Chemistry, ;2024, 40(12): 2455-2465. doi: 10.11862/CJIC.20240192 shu

Crystal structures, DNA action, and antibacterial activities of three tetranuclear lanthanide-based complexes

Changqing MIAO ¹ ,
Fengjiao CHEN ^{1, 2} ,
Wenyu LI ^{1, 2} ,
Shujie WEI ^{1, 2} ,
Yuqing YAO ^{1, 2} ,
Keyi WANG ^{1, 2} ,
Ni WANG ^1,, ,
Xiaoyan XIN ^{1, 2,,} ,
Ming FANG ^3,,

1.
Department of Chemistry, Xinzhou Normal University, Xinzhou, Shanxi 034000, China
2.
College of Chemistry and Materials, Taiyuan Normal University, Jinzhong, Shanxi 030619, China
3.
Department of Chemistry, Hebei Normal University of Science & Technology, Qinhuangdao, Hebei 066004, China

Corresponding author: Ni WANG, wangniemail@126.com Xiaoyan XIN, 1624889278@qq.com Ming FANG, fangmingchem@163.com
Received Date: 25 May 2024
Revised Date: 8 October 2024

Figures(10)

Three new tetranuclear lanthanide-based complexes, namely [Ln₄(dbm)₆(L)₂(μ₂-OCH₃)₂(CH₃OH)₂] · xCH₃OH [Ln=Eu (1), Tb (2), and Tm (3); x=3 (1), 0 (2), and 0 (3); Hdbm=dibenzoylmethane], were successfully designed and constructed by using a polydentate Schiff base (E)-2-hydroxy-3-methoxy-N'-(6-methoxy-pyridine-2-methylene)benzoylhydrazine (H₂L) reacting with Ln(dbm)₃·6H₂O via solvothermal method. Single crystal X-ray diffraction analysis shows that the coordination units of1-3 comprise four Ln^Ⅲ ions, six dbm^- ligands, two L^2- ligands, two μ₂ -OCH₃ ligands, and two coordinated CH₃OH molecules. Four central Ln^Ⅲ ions are interlinked by six μ₂-O atoms displaying a linear tetranuclear structure. Solid fluorescence tests show that1 and2 exhibited fluorescence emission peaks of Ln(Ⅲ) ions at room temperature. In addition, antibacterial studies indicate that1-3 had stronger antibacterial activity than ligand H₂L and Ln(Ⅲ) ions. The interaction between1-3 and calf thymus DNA (CT-DNA) was studied by ultraviolet spectroscopy, cyclic voltammetry, and fluorescence spectrometry. The results indicate that1-3 are primarily intercalated with CT-DNA.
- tetranuclear lanthanide-based complexes,
- crystal structures,
- fluorescence properties,
- DNA-binding,
- antibacterial activities
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