Citation: Haitang WANG, Yanni LING, Xiaqing MA, Yuxin CHEN, Rui ZHANG, Keyi WANG, Ying ZHANG, Wenmin WANG. Construction, crystal structures, and biological activities of two Ln^Ⅲ₃ complexes[J]. Chinese Journal of Inorganic Chemistry, ;2024, 40(8): 1474-1482. doi: 10.11862/CJIC.20240188 shu

Construction, crystal structures, and biological activities of two Ln^Ⅲ₃ complexes

Haitang WANG ¹ ,
Yanni LING ² ,
Xiaqing MA ² ,
Yuxin CHEN ² ,
Rui ZHANG ² ,
Keyi WANG ² ,
Ying ZHANG ¹ ,
Wenmin WANG ^2,,

1.
Department of Energy Chemistry and Materials Engineering, Shanxi Institute of Energy, Jinzhong, Shanxi 030600, China
2.
College of Chemistry and Materials, Taiyuan Normal University, Jinzhong, Shanxi 030619, China

Corresponding author: Wenmin WANG, wangwenmin0506@126.com
Received Date: 21 May 2024
Revised Date: 19 June 2024

Figures(9)

Two new trinuclear Ln-based complexes with the formula [Ln₃(dbm)₅(L)₂(CH₃OH)₂]·CH₂Cl₂ (Ln=Pr (1), Ho (2); Hdbm=dibenzoylmethane) have been constructed via the solvothermal method by using a polydentate Schiff base ligand H₂L (H₂L=(E)-6-(hydroxymethyl)-N′-((6-methoxypyridin-2-yl)methylene)picolinohydrazide) reacting with Ln(dbm)₃·2H₂O. Single-crystal X-ray diffraction reveals that complexes 1 and 2 are isostructural, and their structures are mainly composed of three Ln(Ⅲ) ions, five dbm^- ions, two L^2- ions, two coordinated CH₃OH molecules, and one lattice CH₂Cl₂ molecule. The three central Ln(Ⅲ) ions are connected by four μ₂-O atoms forming a folded Ln₃ core. Notably, complexes 1 and 2 show promising antibacterial activity and exhibit stronger bacteriostatic activities compared to their precursor components. Additionally, their interaction with calf thymus DNA (ctDNA) was studied using ultraviolet spectroscopy, cyclic voltammetry, and fluorescence spectroscopy, demonstrating their ability to bind to ctDNA mainly by intercalation.
- lanthanide complexes,
- Schiff base ligand,
- crystal structures,
- biological activities,
- DNA-binding
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沈阳化工大学材料科学与工程学院沈阳 110142

Construction, crystal structures, and biological activities of two LnⅢ3 complexes

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Construction, crystal structures, and biological activities of two Ln^Ⅲ₃ complexes