Citation: Xiaofen GUAN, Yating LIU, Jia LI, Yiwen HU, Haiyuan DING, Yuanjing SHI, Zhiqiang WANG, Wenmin WANG. Synthesis, crystal structure, and DNA-binding of binuclear lanthanide complexes based on a multidentate Schiff base ligand[J]. Chinese Journal of Inorganic Chemistry, ;2024, 40(12): 2486-2496. doi: 10.11862/CJIC.20240122 shu

Synthesis, crystal structure, and DNA-binding of binuclear lanthanide complexes based on a multidentate Schiff base ligand

Xiaofen GUAN ¹ ,
Yating LIU ¹ ,
Jia LI ¹ ,
Yiwen HU ¹ ,
Haiyuan DING ¹ ,
Yuanjing SHI ¹ ,
Zhiqiang WANG ^2,, ,
Wenmin WANG ^1,,

1.
College of Chemistry and Materials, Taiyuan Normal University, Jinzhong, Shanxi 030619, China
2.
Basic Department, Shanxi Agricultural University, Jinzhong, Shanxi 030801, China

Corresponding author: Zhiqiang WANG, wzq19910101@163.com Wenmin WANG, wangwenmin0506@126.com
Received Date: 9 April 2024
Revised Date: 23 September 2024

Figures(9)

Two new dinuclear lanthanide(Ⅲ) complexes, namely [Ln₂(dbm)₂(HL)₂(CH₃OH)₂]·4CH₃OH [Ln=Tb (1) and Dy (2), Hdbm=dibenzoylmethane] have been synthesized using prepared multidentate Schiff base ligand H₃L (hydroxy-acetic acid(4-diethylamino-2-hydroxy-benzylidene)-hydrazide) with good biological activity. Structure characterizations show that the complex comprises two Ln³⁺ ions, two dbm^- ions, two HL^2- ligands, two CH₃OH molecules, and four free methanol molecules. Each Ln³⁺ ion is eight-coordinated. The two central Ln(Ⅲ) ions are bridged by two μ₂-O atoms leading to a parallelogram [Ln₂O₂] core. The interaction between the compounds (H₃L, 1, and 2) and the calf thymus DNA (CT-DNA) has been further confirmed by UV-Vis spectrometry, fluorescence titration, and cyclic voltammetry. The results showed that both 1 and 2 could undergo insertion with CT-DNA.
- binuclear lanthanide complexes,
- crystal structures,
- multidentate Schiff base,
- DNA,
- insertion
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