Citation: Yuanyuan LI, Xiulian LU, Xinyu LIU, Lei ZHANG, Su JING. Red-emitting selenium-doped carbon dots for versatile applications in biosensing and antibacterial activities[J]. Chinese Journal of Inorganic Chemistry, ;2024, 40(1): 173-181. doi: 10.11862/CJIC.20230360 shu

Red-emitting selenium-doped carbon dots for versatile applications in biosensing and antibacterial activities

School of Chemistry and Molecular Engineering, Nanjing Tech University, Nanjing 211816, China

Corresponding author: Lei ZHANG, ias_lzhang@njtech.edu.cn Su JING, sjing@njtech.edu.cn
Received Date: 2 October 2023
Revised Date: 17 December 2023

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In this study, we successfully designed and synthesized selenium-doped carbon dots (Se-CDs) using easily available precursors of benzeneseleninic acid (BA) and o-phenylenediamine (o-PDA) through a one-step hydrothermal method. These Se-CDs emitted red-wavelength fluorescence and were utilized to develop a sensitive fluorescence sensor for detecting microRNA-21 (miR-21). By incorporating deoxyribonuclease Ⅰ (DNase Ⅰ)-mediated signal amplification, the detection limit for miR -21 was improved from 78 to 6.8 nmol·L^-1. Furthermore, we observed desirable inhibitory activity of the Se-CDs against Gram-negative bacteria of Escherichia coli (E. coli).
- selenium-doped carbon dots,
- red fluorescence,
- biosensing,
- microRNA-21,
- antibacterial
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