Citation: Xiang-Ping WEN, La-Zhen SHEN, Jian-Hui LI, Xiao-Li GAO, Yi-Kun LI, Xin ZHANG, Jia-Yu LÜ. Nitrogen-doped fluorescent carbon dots are used for ultra-sensitive detection of Co²⁺ and cell imaging[J]. Chinese Journal of Inorganic Chemistry, ;2023, 39(8): 1471-1480. doi: 10.11862/CJIC.2023.133 shu

Nitrogen-doped fluorescent carbon dots are used for ultra-sensitive detection of Co²⁺ and cell imaging

Department of Chemistry and Materials, Taiyuan Normal University, Jinzhong, Shanxi 030619, China

Corresponding author: Xiang-Ping WEN, wenxiangping99@163.com
Received Date: 8 April 2023
Revised Date: 26 June 2023

Figures(9)

For the first time, nitrogen-doped carbon dots (N-CDs) with excellent properties were synthesized by hydrothermal method using honeysuckle as a carbon source and ethylenediamine as a nitrogen source. The prepared N-CDs have abundant functional groups, small particle sizes, good water solubility, excellent fluorescence performance, and high chemical stability. They can emit bright blue fluorescence under ultraviolet light. Using quinine sulfate as a reference, the fluorescence quantum yield of N-CDs was measured to be as high as 15.6%. Under optimal conditions, N-CDs could selectively detect Co²⁺, and the fluorescence intensity of N-CDs was linearly quenched by Co²⁺ in a range of 0.5 to 3.6 nmol·L^-1, with a detection limit as low as 1.38 nmol·L^-1. The quenching mechanism belongs to the internal filtering effect and static quenching. Therefore, an ultra-sensitive Co²⁺ detection method has been established. To further confirm the feasibility of this sensor, we have also successfully applied it to the precise analysis of Co²⁺ in tap water samples. In addition, N-CDs have been successfully used for cell imaging and intracellular Co²⁺ sensing due to their low cytotoxicity and good biocompatibility.
- nitrogen-doped carbon dots,
- Co²⁺,
- hydrothermal method,
- sensing,
- cell imaging
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通讯作者: 陈斌, bchen63@163.com

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沈阳化工大学材料科学与工程学院沈阳 110142

Nitrogen-doped fluorescent carbon dots are used for ultra-sensitive detection of Co2+ and cell imaging

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通讯作者: 陈斌, bchen63@163.com

Nitrogen-doped fluorescent carbon dots are used for ultra-sensitive detection of Co²⁺ and cell imaging