Citation: Yi-Min SUN, Zhan-Peng WANG, Peng-Fei TONG, Fei XIAO. Application of MXene for precise cancer diagnosis and treatment[J]. Chinese Journal of Inorganic Chemistry, ;2023, 39(8): 1441-1462. doi: 10.11862/CJIC.2023.103 shu

Application of MXene for precise cancer diagnosis and treatment

1.
Hubei Key Laboratory of Plasma Chemistry and Advanced Materials, Wuhan Institute of Technology, Wuhan 430205, China
2.
Henan Institute of Microsurgery, The First Affiliated Hospital, and College of Clinical Medicine of Henan University of Science and Technology, Luoyang, Henan 471003, China
3.
Key Laboratory of Material Chemistry for Energy Conversion and Storage, Ministry of Education, School of Chemistry and Chemical Engineering, Huazhong University of Science and Technology, Wuhan 430205, China

Corresponding author: Yi-Min SUN, ymsun@wit.edu.cn Fei XIAO, xiaofei@hust.edu.cn
Received Date: 10 October 2022
Revised Date: 17 April 2023

Figures(8)

Cancer is the second health-threatening risk for humans. Accurate screening and diagnosis technology as well as efficient treatment approaches are the key factors to cure cancer. The rapid development of nanotechnology has brought new ideas and fresh perspectives to cancer diagnosis and treatment. MXene, as a new two-dimensional material, possesses a large specific surface area, high conductivity, good hydrophilicity, and excellent biocompatibility. It can be used as an excellent substrate material to construct a biosensor platform with high compatibility and catalytic performance by combining it with other nanomaterials for the accurate detection of cancer biomarkers. In addition, MXene is an ideal tumor photothermal therapy (PTT) reagent with adjustable components, strong absorption, and high photothermal conversion efficiency in the visible-to-infrared region. To date, few reviews regarding the application of MXene in cancer diagnosis and treatment are reported. In view of this, we summarize the recent advances of Mxene-based biosensing platforms for the detection of different cancer markers, and also conclude the latest research progress of different MXene materials in PTT, and then put forward the challenges and development trends of MXene in cancer diagnosis and treatment.
- MXene,
- cancer biomarkers,
- electrochemical sensing,
- cancer diagnosis,
- cancer treatment
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