Citation: Qing-Mei ZHANG, Lu-Peng ZHANG, Kai-Wen ZHENG, Guo-Qing YANG, Song-Jie HE, Xiu-Juan DU, Feng-Hua CHEN, Bing LI. Green synthesis of high-stability black rice carbon dots for application in cell imaging[J]. Chinese Journal of Inorganic Chemistry, ;2023, 39(4): 735-745. doi: 10.11862/CJIC.2023.045 shu

Green synthesis of high-stability black rice carbon dots for application in cell imaging

1.
School of Applied Science, Taiyuan University of Science and Technology, Taiyuan 030024, China
2.
Hospital of Stomatology, Shanxi Medical University, Taiyuan 030001, China

Corresponding author: Bing LI, Libing-1975@163.com
Received Date: 21 September 2022
Revised Date: 15 March 2023

Figures(6)

Carbon dots (CDs) were synthesized by a facile hydrothermal method using cheap black rice as a carbon source.The synthesized CDs exhibited excellent stability, which was not sensitive to changes in temperature, pH, and solution of NaCl, and were immune to many metal ions.The purified CDs also had low cytotoxicity against human oral keratinocytes (Hok), cancer cells (cervical cancer, Hela), and bone marrow mesenchymal stem (BMSC, MC3T3) cells.Meanwhile, it behaved with excitation-independent behavior in the shorter wavelength range (410-470 nm) and excitation-dependent behavior in the longer wavelength range (470-510 nm).Due to the excellent fluorescence properties and stability, we applied them to the intracellular imaging of Hok, Hela, and MC3T3 cells.
- black rice carbon dots,
- fluorescence properties,
- stability,
- cell imaging
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