Citation: Xi CHEN, Si-Yuan LI, Yuan WANG, Wei-Na WU, Zhong CHEN. A Schiff Base Fluorescent Probe for Al³⁺: Synthesis and Application in Living Cells Imaging[J]. Chinese Journal of Inorganic Chemistry, ;2022, 38(10): 1993-1998. doi: 10.11862/CJIC.2022.190 shu

A Schiff Base Fluorescent Probe for Al³⁺: Synthesis and Application in Living Cells Imaging

Xi CHEN ¹ ,
Si-Yuan LI ² ,
Yuan WANG ¹ ,
Wei-Na WU ^1,, ,
Zhong CHEN ^2,,

1.
College of Chemistry and Chemical Engineering, Henan Polytechnic University, Jiaozuo, Henan 454000, China
2.
School of Materials and Mechanical and Electrical Engineering, Jiangxi Science and Technology Normal University, Nanchang 330013, China

Corresponding author: Wei-Na WU, wangyuan08@hpu.edu.cn Zhong CHEN, chenzhonglzu@hotmail.com
Received Date: 8 March 2022
Revised Date: 3 August 2022

Figures(9)

A fluorescent probe 1 has been synthesized by the Schiff base condensation of 4-(diethylamino)salicylaldehyde with oxamic hydrazide, which has been carefully characterized through ¹H NMR, ¹³C NMR, and electrospray ionization mass spectrometer. Probe 1 exhibited a quite weak emission at 495 nm, which could selectively and sensitively recognize Al3+ from other cations by a notable fluorescence enhancement. The limit of detection of probe 1 for Al³⁺ was as low as 1.44 μmol·L^-1, indicating its high sensitivity. Based on theory calculation results, probe 1 is proposed to coordinate with Al with the ratio of 1∶1 in a tridentate mode. Moreover, the probe was applied to imaging Al³⁺ in living cells.
- fluorescent probe,
- cell imaging,
- Schiff base,
- Al³⁺
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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

A Schiff Base Fluorescent Probe for Al3+: Synthesis and Application in Living Cells Imaging

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通讯作者: 陈斌, bchen63@163.com

A Schiff Base Fluorescent Probe for Al³⁺: Synthesis and Application in Living Cells Imaging