Citation: XIE Bo, YAO Hua, LIAO Qi-Hua, DENG Rui-Hong, LIN Sen, YAN Zhao-Hua. Synthesis, Structure and Antitumour Activity of Diorganotin(Ⅳ) Complexes Containing Silicon of Salicylaldehyde Thiosemicarbazone[J]. Chinese Journal of Inorganic Chemistry, ;2020, 36(5): 819-826. doi: 10.11862/CJIC.2020.101 shu

Synthesis, Structure and Antitumour Activity of Diorganotin(Ⅳ) Complexes Containing Silicon of Salicylaldehyde Thiosemicarbazone

College of Chemistry, Nanchang University, Nanchang 330031, China

Corresponding author: LIN Sen, senlin@ncu.edu.cn
Received Date: 17 October 2019
Revised Date: 27 December 2019

Figures(2)

Eleven diorganotins containing silicon of salicylaldehyde thiosemicarbazone were synthesized and characterized through ¹H NMR, ¹³C NMR, IR spectra, elemental analysis and X-ray single crystal diffraction tests. The result shows that the thiosemicarbazone Schiff base coordinates with tin atom as tridentate dianionic ligand through thephenolic oxygen, imine nitrogen and mercaptan sulfur, forming a parallel five and six-member heterocyclic structures. The preliminary bioassay result shows that these compounds have a good antitumor activity in vitro against MDA-MB-231 and MCF-7.
- diorganotin,
- thiosemicarbazone,
- Schiff base,
- synthesis,
- structure,
- biological activity
1. [1]
  Arjmand F, Sharma S, Usman M, et al. Phys. Chem. Chem. Phys., 2016, 18:17805-17809 doi: 10.1039/C6CP02914K
2. [2]
  Mirna B Z, Danijela M I, Bensing C, et al. Angew. Chem. Int. Ed., 2014, 53:5982-5987 doi: 10.1002/anie.201400763
3. [3]
  Shpakovsky D B, Banti C N, Mukhatova E M, et al. Dalton Trans., 2014, 43:6880-6890 doi: 10.1039/C3DT53469C
4. [4]
  ZHANG Fu-Xing, HE Tang-Feng, YAO Shu-Fen, et al. Chinese J. Inorg. Chem., 2019, 35(4):598-604
5. [5]
  XIE Yun-Fu, YU Yang, TANG Liang-Fu. Chinese J. Inorg. Chem., 2018, 34(12):2291-2297 doi: 10.11862/CJIC.2018.273
6. [6]
  Rais A K, Shipra Y, Zahid H, et al. Dalton Trans., 2014, 43:2534-2548 doi: 10.1039/C3DT51973B
7. [7]
  Shpakovsky D B, Banti C N, Beaulieu-Houle G, et al. Dalton Trans., 2012, 41:14568-14582 doi: 10.1039/c2dt31527k
8. [8]
  Hong M, Yang Y G, Li C, et al. RSC Adv., 2015, 5:102885-102894 doi: 10.1039/C5RA18445B
9. [9]
  Arelly M C, Blanca M M, Ivana M, et al. New J. Chem., 2018, 42:14586-14596 doi: 10.1039/C8NJ02998A
10. [10]
  Navjot S, Keshav K, Neha S, et al. New J. Chem., 2018, 42:8756-8764 doi: 10.1039/C8NJ01153B
11. [11]
  Jessica C B, Blanca M M, Abigail M P. New J. Chem., 2019, 43:5150-5158 doi: 10.1039/C8NJ05248D
12. [12]
  Nath M, Saini P K. Dalton Trans., 2011, 40:7077-7121 doi: 10.1039/c0dt01426e
13. [13]
  Dong X W, Li Y G, Li Z W, et al. J. Inorg. Biochem., 2012, 108:22-29 doi: 10.1016/j.jinorgbio.2011.12.006
14. [14]
  Jagadeesh M, Lavanya M, Kalangi S K, et al. Spectrochim. Acta Part A, 2015, 135:180-184 doi: 10.1016/j.saa.2014.06.141
15. [15]
  Kumar D, Singh D V K. J. Drug Delivery Sci. Technol., 2014, 2(13):24-32
16. [16]
  Zhang Y H, Zhang N, Li Y K, et al. Synth. React. Inorg. Met.-Org. Chem., 2014, 45(2):191-195
17. [17]
  Sedaghat T, Golalzadeh A, Motamedi H. Phosphorus Sulfur Rel. Elem., 2013, 188:1694-1702 doi: 10.1080/10426507.2013.777727
18. [18]
  Khandani M, Sedaghat T, Erfani N, et al. J. Mol. Struct., 2013, 1037:136-143 doi: 10.1016/j.molstruc.2012.12.061
19. [19]
  LIN Sen, DENG Rui-Hong, LU Zhi-Qiang, et al. Chinese J. Org. Chem., 2005, 25(10):1298-1301 doi: 10.3321/j.issn:0253-2786.2005.10.025
20. [20]
  GONG Gen-Fei, SONG Ran, ZOU Yin-Bo, et al. Chinese J. Org. Chem., 2013, 33:803-807 doi: 10.6023/cjoc201302004
21. [21]
  LIN Sen, XU Song, DENG Rui-Hong, et al. Chemical Reagents, 2008, 30(12):897-890 doi: 10.3969/j.issn.0258-3283.2008.12.006
22. [22]
  Klayman D L, Bartosevich J F, Graffin T S, et al. J. Med. Chem., 1979, 22(7):855-862 doi: 10.1021/jm00193a020
23. [23]
  LIN Sen, FU Zhi-Fei, HE Xiao-Li, et al. Chinese J. Org. Chem., 2006, 26:856-859 doi: 10.3321/j.issn:0253-2786.2006.06.018
24. [24]
  Sheldrick G M. SHELX-97, Program for the Solution and the Refinement of Crystal Structures, University of Göttingen, Germany, 1997.
25. [25]
  Affan M A, Salam M A, Ahmad F B, et al. Inorg. Chim. Acta, 2011, 366:227-232 doi: 10.1016/j.ica.2010.11.002
26. [26]
  Mendes I C, Moreira J P, Speziali, et al. J. Braz. Chem. Soc., 2006, 17:1571-1577 doi: 10.1590/S0103-50532006000800013
27. [27]
  Rebolledo A P, Vieites M, Gambino D, et al. J. Inorg. Biochem., 2005, 99:698-706 doi: 10.1016/j.jinorgbio.2004.11.022
28. [28]
  Yin H D, Chen S W, Li L W, et al. Inorg. Chim. Acta, 2007, 360:2215-2223 doi: 10.1016/j.ica.2006.10.038
29. [29]
  Casaa J S, Castineiras A, Martinez E G, et al. Polyhedron, 1997, 16:795-800 doi: 10.1016/S0277-5387(96)00341-5
30. [30]
  Zhang R F, Wang Q F, Li Q L, et al. Inorg. Chim. Acta, 2009, 362:2762-2769 doi: 10.1016/j.ica.2008.12.017
31. [31]
  Seena E B, Kurup M R P, Suresh E. J. Chem. Crystallogr., 2007, 38:93-96 doi: 10.1007/s10870-007-9268-8
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