Citation: QU Xing-Yu, BIAN Yong-Jun, BAI Yang, SHEN Zhen. A Visible BODIPY Probe for 'Naked-Eye' Detection of pH Value and Intracellular Fe³⁺[J]. Chinese Journal of Inorganic Chemistry, ;2019, 35(4): 649-657. doi: 10.11862/CJIC.2019.089 shu

A Visible BODIPY Probe for 'Naked-Eye' Detection of pH Value and Intracellular Fe³⁺

1.
Department of Chemistry and Chemical Engineering, Jinzhong University, Jinzhong, Shanxi 030619, China
2.
School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210093, China

Corresponding author: BIAN Yong-Jun, zshen@nju.edu.cn; yjbian2013@jzxy.edu.cn
Received Date: 1 November 2018
Revised Date: 30 January 2019

Figures(11)

A fluorescence probe 2 containing 4-hydroxystyryl at the 3-position on the boron fluoride dipyrromethene(BODIPY) fluorophore was successfully synthesized in high yield using the 4-formylphenyl picolinate as the starting material instead of 4-hydroxybenzaldehyde. Probe 2 exhibits excellent optical performance, including good solubility, high extinction coefficient and high fluorescence quantum yield (Ф=0.90 in CH₃OH). The absorption and emission bands of probe 2 are centered at 570 and 585 nm in CH₃OH, respectively. When the pH value of the solution changes from acidity to basicity, both positive fluorescence response and visual color change make naked-eye detection of pH value possible due to the deprotonation of hydroxyl group. With the addition of Fe³⁺ ions into the solution, visual color changes and blue shift of the absorption and fluorescence peak were detected as well. Hence, the probe 2 could also be used as a ratiometric fluorescent probe for selectively monitoring Fe³⁺ ion in solution and in living cells.
- BODIPY dyes,
- pH probe,
- fluorescent probe,
- probe for Fe³⁺,
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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

A Visible BODIPY Probe for 'Naked-Eye' Detection of pH Value and Intracellular Fe3+

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通讯作者: 陈斌, bchen63@163.com

A Visible BODIPY Probe for 'Naked-Eye' Detection of pH Value and Intracellular Fe³⁺