Citation: WU Hao, WANG Yuan, SONG Yu-Fei, ZHANG Ling, WU Wei-Na. Syntheses, Crystal Structures and DNA-Binding Properties of Ni(Ⅱ)/Co(Ⅲ) Complexes with Pyrazine Thiosemicarbazone Ligand[J]. Chinese Journal of Inorganic Chemistry, ;2018, 34(11): 2057-2062. doi: 10.11862/CJIC.2018.253 shu

Syntheses, Crystal Structures and DNA-Binding Properties of Ni(Ⅱ)/Co(Ⅲ) Complexes with Pyrazine Thiosemicarbazone Ligand

College of Chemistry and Chemical Engineering, Henan Key Laboratory of Coal Green Conversion, Henan Polytechnic University, Jiaozuo, Henan 454000, China

Corresponding author: WANG Yuan, wangyuan08@hpu.edu.cn WU Wei-Na, wuwn08@hpu.edu.cn
Received Date: 13 June 2018
Revised Date: 24 August 2018

Figures(4)

Two complexes[Ni(L)(OAc)] (1) and[Co(L)₂]Cl·4CH₃OH (2) (HL=2-aceto-3-methylpyrazine N-(4-fluorophenyl)thiosemicarbazone) have been synthesized and structurally determined by single-crystal X-ray diffraction, elemental analysis and IR spectroscopy.X-ray diffraction analysis results show that the Ni(Ⅱ) ion in complex 1 with a distorted square planar geometry is surrounded by one anionic TSC ligand with NNS donor set and one monodentate acetate.By contrast, Co(Ⅲ) ion coordinates with two tridentate TSC ligands, and thus possessing a distorted octahedron coordination geometry.Moreover, the fluorescence spectra indicate that the interactions of complexes 1 and 2 with DNA are stronger than that of the ligand HL.
- Co(Ⅲ) complex,
- DNA-binding,
- Ni(Ⅱ) complex,
- pyrazine,
- thiosemicarbazone
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