Citation: ZHANG Ze-Fang, YUAN Wei, XU Ming, YI Tao, ZHANG Shan-Duan, Li Fu-You. Silica-Copolymer Hybrid Nanocomposite for Animal Bioimaging[J]. Chinese Journal of Inorganic Chemistry, ;2018, 34(11): 1943-1949. doi: 10.11862/CJIC.2018.250 shu

Silica-Copolymer Hybrid Nanocomposite for Animal Bioimaging

ZHANG Ze-Fang ¹ ,
YUAN Wei ² ,
XU Ming ² ,
YI Tao ^3,, ,
ZHANG Shan-Duan ¹ ,
Li Fu-You ^2,,

1.
Engineering Research Center of Advanced Lighting Technology, Ministry of Education, Fudan University, Shanghai 200433, China
2.
Department of Chemistry, Fudan University, Shanghai 200433, China
3.
Department of Integrative Medicine, Huashan Hospital, Fudan University, Shanghai 200040, China

Corresponding author: YI Tao, yt13817969911@163.com Li Fu-You, fyli@fudan.edu.cn
Received Date: 14 May 2018
Revised Date: 5 September 2018

Figures(10)

Near-infrared nanometer probe (M507@SNP) is obtained by monomer self-assembly between silica precursor and triblock copolymer F108 and then doping hydrophobic near-infrared dye M507. The photophysical properties and cytotoxicity of M507@SNP are investigated. Furthermore, M507@SNP is used as a fluorescent nanoprobe for monitoring whole-body and sentinel lymph node of rodents with high signal-to-noise.
- hybrid composite,
- fluorescent bioimaging,
- hollow silica nanoparticle,
- near-infrared dye
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沈阳化工大学材料科学与工程学院沈阳 110142