Citation: WANG Wan-Wan, WANG Yuan, YU Ya-Ping, SONG Yu-Fei, WU Wei-Na. Ni(Ⅱ)/Zn(Ⅱ) Complexes with 1-(3-Ethylpyrazin-2-yl)ethylidene)-4-methylthiosemicarbazide: Crystal Structures and DNA-Binding Properties[J]. Chinese Journal of Inorganic Chemistry, ;2018, 34(8): 1511-1516. doi: 10.11862/CJIC.2018.196 shu

Ni(Ⅱ)/Zn(Ⅱ) Complexes with 1-(3-Ethylpyrazin-2-yl)ethylidene)-4-methylthiosemicarbazide: Crystal Structures and DNA-Binding Properties

College of Chemistry and Chemical Engineering, Henan Key Laboratory of Coal Green Conversion, Henan Polytechnic University, Jiaozuo, Henan 454000, China

Corresponding author: WANG Yuan, wangyuan08@hpu.edu.cn WU Wei-Na, wuwn08@hpu.edu.cn
Received Date: 29 December 2017
Revised Date: 12 June 2018

Figures(4)

Two complexes[NiL(HL)](OAc) (1) and[ZnL(OAc)]_n (2) (HL=1-(3-ethylpyrazin-2-yl)ethylidene)-4-methylthiosemicarbazide) have been synthesized and structurally determined by single-crystal X-ray diffraction. The results show that the Ni(Ⅱ) ion in 1 is surrounded by two independent thiosemicarbazone ligands with N₄S₂ donor set, one of which is anionic. However, in complex 2, the Zn(Ⅱ) ion with a distorted tetragonal pyramid coordination geometry is five-coordinated, involving two μ-OCO acetate anions, one tridentate enolizated ligand L^-, thus forming one dimension chain-like framework along a axis. Moreover, the fluorescence spectra indicate that the interactions of the complexes with DNA are stronger than that of the thiosemicarbazone ligand.
- pyrazine,
- thiosemicarbazone,
- complex,
- crystal structure,
- DNA-binding property
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