Citation: FENG Yong-Lan, KUANG Dai-Zhi, ZHANG Fu-Xing, YU Jiang-Xi, JIANG Wu-Jiu, ZHU Xiao-Ming. Microwave-Solvothermal Syntheses, Crystal Structures and in Vitro Antitumor Activities of Two Bis[oxo-bis (aromatic carboxylato dibutyltin)][J]. Chinese Journal of Inorganic Chemistry, ;2017, 33(4): 589-594. doi: 10.11862/CJIC.2017.071 shu

Microwave-Solvothermal Syntheses, Crystal Structures and in Vitro Antitumor Activities of Two Bis[oxo-bis (aromatic carboxylato dibutyltin)]

Key Laboratory of Functional Organometallic Materials of Hengyang Normal University, Colleges of Hunan Province, College of Chemistry and Material Science, Hengyang Normal University, Hengyang, Hunan 421008, China

Corresponding author: KUANG Dai-Zhi, hnkcq@qq.com
Received Date: 25 September 2016
Revised Date: 7 January 2017

Figures(3)

Two di-n-butyltin compounds with μ₃-O bridging the framework, [(μ₃-O)(n-Bu₂Sn)₂(O₂CR)₂]₂(R=4-(t-Bu)-C₆H₅ (1), (3-Me-4-NH₂)-C₆H₄ (2)), were obtained by microwave-assisted solvothermal reaction of di-n-butyltin oxide precursor with the aromatic acid in methanol environments, which have been structurally characterized by elemental analysis, IR and NMR (¹H, ¹³C and ¹¹⁹Sn) spectra and X-ray crystallography diffraction analyses. This compound was of a centrosymmetric dimer structure mode with a four-membered central endo-cyclic Sn2O₂ unit in which the bridging oxygen atoms were tri-coordinated. Each bridging oxygen atom also connects with an exo-cyclic tin atom. The endo-cyclic and exo-cyclic tin atoms all were five-coordinated with distorted trigonal bipyramid geometry. The compounds 1 and 2 have strong anti-tumor activity in vitro.
- organotin compound,
- microwave solvothermal synthesis,
- in vitro antitumor activity
1. [1]
  Hadjikakou S K, Hadjiliadis N. Coord. Chem. Rev., 2009, 253:235-249 doi: 10.1016/j.ccr.2007.12.026
2. [2]
  Evans C J, Smith P J. Chemistry of Tin. London:Blackie Academic and Professional, 1998:442
3. [3]
  Gielen M. Tin-Based Antitumor Drugs. Berlin:Springer Verlag, 1990:69-75
4. [4]
  SHANG Xian-Mei, WU Jun, LI Qing-Shan. Sci. China B:Chem., 2008, 38(5):429-440
5. [5]
  JIANG Wu-Jiu, TAN YU-Xing, YU Jiang-Xi, et al. Chinese J. Inorg. Chem., 2016, 32(8):1383-1390
6. [6]
  Gielen M, Boualam M B, Tiekink E B T. Appl. Organomet. Chem., 1994, 8:19-23 doi: 10.1002/aoc.v8:1
7. [7]
  Vadapali C, Viswanathan B, Alexander S, et al. Organomet-allics, 2002, 21:4528 doi: 10.1021/om020531r
8. [8]
  Chandrasekhar P, Gopal K, Thilagar P. Acc. Chem. Res., 2007, 40:420-434 doi: 10.1021/ar600061f
9. [9]
  Chandrasekhar V, Mohapatra C, Butche R J. Cryst. Growth Des., 2012, 12:3285-3295 doi: 10.1021/cg3004189
10. [10]
  Chandrasekhar V, Nagendran S, Baskar V. Coord. Chem. Rev., 2002, 235:1-52 doi: 10.1016/S0010-8545(02)00178-9
11. [11]
  Chandrasekhar V, Thilagar P, Bickley J F, et al. J. Am. Chem. Soc., 2005, 127:11556-11557 doi: 10.1021/ja052776b
12. [12]
  Sougoule A S, Mei Z, Xiao X, et al. J. Organomet. Chem., 2014, 758:19-24 doi: 10.1016/j.jorganchem.2014.01.034
13. [13]
  Xiao X, Shao K Z, Yan L S, et al. Dalton Trans., 2013, 42:15387-15390 doi: 10.1039/c3dt50531f
14. [14]
  Sheldrick G M. SHELXL-97, Program for the Refinement of Crystal Structures, University of Göttingen, Germany, 1997.
15. [15]
  YIN Han-Dong, WANG Chuan-Hua, XING Qiu-Ju. Chinese J. Org. Chem., 2004, 24(7):770-774
16. [16]
  Ma C, Sun J, Zhang R, et al. Inorg. Chim. Acta, 2006, 359:4179-4190 doi: 10.1016/j.ica.2006.07.001
17. [17]
  Chandrasekhar V, Thirumoorthi R, Metre R K, et al. J. Organomet. Chem., 2011, 696:600-606 doi: 10.1016/j.jorganchem.2010.09.032
18. [18]
  Ruan B, Tian Y, Zhou H, et al. Inorg. Chim. Acta, 2011, 365:302-308 doi: 10.1016/j.ica.2010.09.024
19. [19]
  Xiao X, Du D, Tian M, et al. J. Organomet. Chem., 2012, 715:54-63 doi: 10.1016/j.jorganchem.2012.05.038
20. [20]
  Yoder C H, Margolis L A, Horne J M. J. Organomet. Chem., 2001, 633:33-38 doi: 10.1016/S0022-328X(01)01073-7
21. [21]
  Delavaux-Nicot B, Kaeser A, Hahn U, et al. J. Mater. Chem., 2008, 18:1547-1554 doi: 10.1039/b716506d
22. [22]
  Ma C, Zhang Q, Zhang R, et al. Chem. Eur. J., 2006, 12:420-428 doi: 10.1002/(ISSN)1521-3765
23. [23]
  Shang X, Ding N, Xiang G. Eur. J. Med. Chem., 2012, 48:305-312 doi: 10.1016/j.ejmech.2011.12.032
24. [24]
  Motswainyana W M, Onani M O, Madiehe A M. Polyhedron, 2012, 41:44-51 doi: 10.1016/j.poly.2012.04.010
25. [25]
  Kaluđerović G N, Paschke R, Prashar S, et al. J. Organomet. Chem., 2010, 695:1883-1890 doi: 10.1016/j.jorganchem.2010.04.029
1. [1]
  Jingjing QING , Fan HE , Zhihui LIU , Shuaipeng HOU , Ya LIU , Yifan JIANG , Mengting TAN , Lifang HE , Fuxing ZHANG , Xiaoming ZHU . Synthesis, structure, and anticancer activity of two complexes of dimethylglyoxime organotin. Chinese Journal of Inorganic Chemistry, 2024, 40(7): 1301-1308. doi: 10.11862/CJIC.20240003
2. [2]
  Qiuyang LUO , Xiaoning TANG , Shu XIA , Junnan LIU , Xingfu YANG , Jie LEI . Application of a densely hydrophobic copper metal layer in-situ prepared with organic solvents for protecting zinc anodes. Chinese Journal of Inorganic Chemistry, 2024, 40(7): 1243-1253. doi: 10.11862/CJIC.20240110
3. [3]
  Xiaoling LUO , Pintian ZOU , Xiaoyan WANG , Zheng LIU , Xiangfei KONG , Qun TANG , Sheng WANG . Synthesis, crystal structures, and properties of lanthanide metal-organic frameworks based on 2, 5-dibromoterephthalic acid ligand. Chinese Journal of Inorganic Chemistry, 2024, 40(6): 1143-1150. doi: 10.11862/CJIC.20230271
4. [4]
  Yuanpei ZHANG , Jiahong WANG , Jinming HUANG , Zhi HU . Preparation of magnetic mesoporous carbon loaded nano zero-valent iron for removal of Cr(Ⅲ) organic complexes from high-salt wastewater. Chinese Journal of Inorganic Chemistry, 2024, 40(9): 1731-1742. doi: 10.11862/CJIC.20240077
5. [5]
  Xinting XIONG , Zhiqiang XIONG , Panlei XIAO , Xuliang NIE , Xiuying SONG , Xiuguang YI . Synthesis, crystal structures, Hirshfeld surface analysis, and antifungal activity of two complexes Na(Ⅰ)/Cd(Ⅱ) assembled by 5-bromo-2-hydroxybenzoic acid ligands. Chinese Journal of Inorganic Chemistry, 2024, 40(9): 1661-1670. doi: 10.11862/CJIC.20240145
6. [6]
  Wenxiu Yang , Jinfeng Zhang , Quanlong Xu , Yun Yang , Lijie Zhang . Bimetallic AuCu Alloy Decorated Covalent Organic Frameworks for Efficient Photocatalytic Hydrogen Production. Acta Physico-Chimica Sinica, 2024, 40(10): 2312014-. doi: 10.3866/PKU.WHXB202312014
7. [7]
  Peiran ZHAO , Yuqian LIU , Cheng HE , Chunying DUAN . A functionalized Eu³⁺ metal-organic framework for selective fluorescent detection of pyrene. Chinese Journal of Inorganic Chemistry, 2024, 40(4): 713-724. doi: 10.11862/CJIC.20230355
8. [8]
  Tiantian MA , Sumei LI , Chengyu ZHANG , Lu XU , Yiyan BAI , Yunlong FU , Wenjuan JI , Haiying YANG . Methyl-functionalized Cd-based metal-organic framework for highly sensitive electrochemical sensing of dopamine. Chinese Journal of Inorganic Chemistry, 2024, 40(4): 725-735. doi: 10.11862/CJIC.20230351
9. [9]
  Wendian XIE , Yuehua LONG , Jianyang XIE , Liqun XING , Shixiong SHE , Yan YANG , Zhihao HUANG . Preparation and ion separation performance of oligoether chains enriched covalent organic framework membrane. Chinese Journal of Inorganic Chemistry, 2024, 40(8): 1528-1536. doi: 10.11862/CJIC.20240050
10. [10]
  Lu XU , Chengyu ZHANG , Wenjuan JI , Haiying YANG , Yunlong FU . Zinc metal-organic framework with high-density free carboxyl oxygen functionalized pore walls for targeted electrochemical sensing of paracetamol. Chinese Journal of Inorganic Chemistry, 2024, 40(5): 907-918. doi: 10.11862/CJIC.20230431
11. [11]
  Jing SU , Bingrong LI , Yiyan BAI , Wenjuan JI , Haiying YANG , Zhefeng Fan . Highly sensitive electrochemical dopamine sensor based on a highly stable In-based metal-organic framework with amino-enriched pores. Chinese Journal of Inorganic Chemistry, 2024, 40(7): 1337-1346. doi: 10.11862/CJIC.20230414
12. [12]
  Youlin SI , Shuquan SUN , Junsong YANG , Zijun BIE , Yan CHEN , Li LUO . Synthesis and adsorption properties of Zn(Ⅱ) metal-organic framework based on 3, 3', 5, 5'-tetraimidazolyl biphenyl ligands. Chinese Journal of Inorganic Chemistry, 2024, 40(9): 1755-1762. doi: 10.11862/CJIC.20240061
13. [13]
  Qilu DU , Li ZHAO , Peng NIE , Bo XU . Synthesis and characterization of osmium-germyl complexes stabilized by triphenyl ligands. Chinese Journal of Inorganic Chemistry, 2024, 40(6): 1088-1094. doi: 10.11862/CJIC.20240006
14. [14]
  Haitang WANG , Yanni LING , Xiaqing MA , Yuxin CHEN , Rui ZHANG , Keyi WANG , Ying ZHANG , Wenmin WANG . Construction, crystal structures, and biological activities of two Ln^Ⅲ₃ complexes. Chinese Journal of Inorganic Chemistry, 2024, 40(8): 1474-1482. doi: 10.11862/CJIC.20240188
15. [15]
  Xin MA , Ya SUN , Na SUN , Qian KANG , Jiajia ZHANG , Ruitao ZHU , Xiaoli GAO . A Tb₂ complex based on polydentate Schiff base: Crystal structure, fluorescence properties, and biological activity. Chinese Journal of Inorganic Chemistry, 2024, 40(7): 1347-1356. doi: 10.11862/CJIC.20230357
16. [16]
  Zhiwen HU , Weixia DONG , Qifu BAO , Ping LI . Low-temperature synthesis of tetragonal BaTiO₃ for piezocatalysis. Chinese Journal of Inorganic Chemistry, 2024, 40(5): 857-866. doi: 10.11862/CJIC.20230462
17. [17]
  Guimin ZHANG , Wenjuan MA , Wenqiang DING , Zhengyi FU . Synthesis and catalytic properties of hollow AgPd bimetallic nanospheres. Chinese Journal of Inorganic Chemistry, 2024, 40(5): 963-971. doi: 10.11862/CJIC.20230293
18. [18]
  Yuhao SUN , Qingzhe DONG , Lei ZHAO , Xiaodan JIANG , Hailing GUO , Xianglong MENG , Yongmei GUO . Synthesis and antibacterial properties of silver-loaded sod-based zeolite. Chinese Journal of Inorganic Chemistry, 2024, 40(4): 761-770. doi: 10.11862/CJIC.20230169
19. [19]
  Chunmei GUO , Weihan YIN , Jingyi SHI , Jianhang ZHAO , Ying CHEN , Quli FAN . Facile construction and peroxidase-like activity of single-atom platinum nanozyme. Chinese Journal of Inorganic Chemistry, 2024, 40(9): 1633-1639. doi: 10.11862/CJIC.20240162
20. [20]
  Yufang GAO , Nan HOU , Yaning LIANG , Ning LI , Yanting ZHANG , Zelong LI , Xiaofeng LI . Nano-thin layer MCM-22 zeolite: Synthesis and catalytic properties of trimethylbenzene isomerization reaction. Chinese Journal of Inorganic Chemistry, 2024, 40(6): 1079-1087. doi: 10.11862/CJIC.20240036

Get Citation

PDF

XML

Metrics

PDF Downloads(1)
Abstract views(428)
HTML views(54)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142