Citation: JIAO Yuan-Hong, ZHANG Qian, JIANG Yu-Feng, ZHANG Wan-Ju. A Benzothiazole-Derived Fluorescent Probe for Detecting Hg(Ⅱ) in Live Cells[J]. Chinese Journal of Inorganic Chemistry, ;2015, (2): 361-368. doi: 10.11862/CJIC.2015.019
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Abenzothiazole-derived fluorescent probe (YH1) has been synthesized and structurally characterized, and its response to different metal ions has been investigated by spectrometry. The results showed that YH1 exhibited good sensitivity and selectivity to Hg2+. Its interaction with Hg2+ caused the color of its solution changed from blue to colorless under UVirradiation. There was a good linear relationship between the fluorescence intensity of YH1 and the concentration of Hg2+ in the range of 1.4 μmol·L-1 to 8.8 μmol·L-1, and its detection limit for Hg2+ was 0.56 μmol·L-1. Moreover, the cell membrane penetration of YH1 had low cytotoxicity, and it can be applied to image intracellular Hg2+ in living HeLa cells. CCDC: 978108.
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