Citation: Qian Yu, Hong Chen. Smart Antibacterial Surfaces with Switchable Function to Kill and Release Bacteria[J]. Acta Polymerica Sinica, ;2020, 51(4): 319-325. doi: 10.11777/j.issn1000-3304.2020.20031 shu

Smart Antibacterial Surfaces with Switchable Function to Kill and Release Bacteria

Qian Yu ^, ,
Hong Chen

College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123

Corresponding author: Qian Yu, yuqian@suda.edu.cn
Received Date: 12 February 2020
Revised Date: 16 February 2020
Available Online: 19 March 2020

Figures(8)

The adhesion of bacteria and the subsequent formation of biofilms on the surfaces of biomaterials cause a series of adverse consequences, resulting in serious problems in both human healthcare and industrial applications. Therefore, endowing the surfaces with antibacterial capabilities has attracted considerable interests and development of antibacterial surfaces has become an active field of research. The traditional antibacterial strategies are mainly focused on killing bacteria attached on the surfaces, however, neglecting many problems raised from the accumulation of dead bacteria and debris such as degradation of biocidal efficiency and secondary contamination. Aiming to solve these problems, a promising smart antibacterial strategy based on switchable function between bacteria-killing and bacteria-releasing was proposed. Based on this strategy, a series of smart antibacterial surfaces have been developed to kill the attached bacteria and then trigger the on-demand release of dead bacteria from the surface by regulation of bacteria-surface interactions, so as to maintain the effective antibacterial activity for long-term applications. In this feature article, we summarize our achievements and the recent progress in the field of smart antibacterial surfaces. These surfaces have been divided into three categories based on the methods for applying biocidal agents on to the surfaces: (1) the surfaces with permanently immobilized biocidal agents; (2) the surfaces with reversibly incorporated biocidal agents; and (3) the surfaces without common biocidal agents but with physically biocidal activity. In the end, we provide a brief perspective of the future research directions in this promising area.
- Antibacterial surface,
- Stimuli-responsive polymer,
- Kill-and-release,
- Responsive biointerface
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