Citation: Jiuhong Li, Xulin Hu, Yuanmeng Chen, Diyi Fan, Chao Tan, Shuhao Yang, Haoming Wu, Yao Wang, Qi An, Zhenghua Xiao, Jia Hu, Jian He, Yongjun Qian, Zhiyong Qian. Review of recent progress in vascular stents: From conventional to functional vascular stents[J]. Chinese Chemical Letters, ;2025, 36(7): 110492. doi: 10.1016/j.cclet.2024.110492 shu

Review of recent progress in vascular stents: From conventional to functional vascular stents

Jiuhong Li ^{a, 1} ,
Xulin Hu ^{a, b, 1} ,
Yuanmeng Chen ^{b, 1} ,
Diyi Fan ^{b, 1} ,
Chao Tan ^b ,
Shuhao Yang ^c ,
Haoming Wu ^b ,
Yao Wang ^b ,
Qi An ^a ,
Zhenghua Xiao ^a ,
Jia Hu ^a ,
Jian He ^d ,
Yongjun Qian ^{a, *,} ,
Zhiyong Qian ^{a, *,}

a.
Department of Cardiovascular Surgery, Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China
b.
Clinical Medical College & Affiliated Hospital of Chengdu University, Chengdu University, Chengdu 610081, China
c.
Department of Orthopedics, The First Affiliated Hospital of Chongqing Medical University, Orthopedics Laboratory of Chongqing Medical University, Chongqing 400016, China
d.
College of Basic Medical and Forensic Medicine, Henan University of Science and Technology, Luoyang 471023, China

yongjunqian@sina.com

anderson-qian@163.com

Received Date: 5 February 2024
Revised Date: 19 September 2024
Accepted Date: 23 September 2024
Available Online: 27 September 2024

Figures(1)

Vascular stents play an important role in the minimally invasive treatment of vascular diseases, such as vascular stenosis, vascular aneurysm, vascular dissection and vascular atherosclerotic plaque disease. Bare metal stents were initially fabricated; however, the incidence of complications such as thrombosis, inflammation, restenosis, vascular injury, displacement and endoleakage is still high after implantation. To overcome these complications, several strategies for designing functional vascular stents have been carried out. Drug-eluting stents, biodegradable stents and bionic stents were manufactured and investigated. This review aims to comprehensively analyze the vascular diseases suitable for stent implantation treatment, tissue reactions after implantation, the materials and manufacturing techniques used to fabricate vascular stents, the various application scenarios in which they could be used to treat vascular lesions and the development process of vascular stents. Future development trends of vascular stents are expected to prioritize their performance, biocompatibility, and clinical accessibility. The design of vascular stents may be transformed or improved to better fulfill the rehabilitation requirements of vascular disease patients. Finally, various application scenarios may be used to treat vascular or even nonvascular diseases via endovascular access.
- Functional vascular stent,
- Manufacturing techniques,
- Vascular diseases,
- Tissue reactions,
- Drug-eluting stents,
- Biodegradable stents,
- Development process
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