Citation: Haibo Wan, Zhengzhong Lv, Jicai Jiang, Xuefeng Cheng, Qingfeng Xu, Haibin Shi, Jianmei Lu. Multidimensional detection of roxarsone via AIE-based sulfates[J]. Chinese Chemical Letters, ;2025, 36(3): 110023. doi: 10.1016/j.cclet.2024.110023 shu

Multidimensional detection of roxarsone via AIE-based sulfates

Haibo Wan ^{a, 1} ,
Zhengzhong Lv ^{b, 1} ,
Jicai Jiang ^a ,
Xuefeng Cheng ^a ,
Qingfeng Xu ^{a, *,} ,
Haibin Shi ^{b, *,} ,
Jianmei Lu ^{a, *,}

a.
College of Chemistry, Chemical Engineering and Materials Science, Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou 215123, China
b.
State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X) and Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Soochow University, Suzhou 215123, China

xuqingfeng@suda.edu.cn

hbshi@suda.edu.cn

lujm@suda.edu.cn

Received Date: 15 March 2024
Revised Date: 14 May 2024
Accepted Date: 16 May 2024
Available Online: 18 May 2024

Figures(7)

Improper abuse of roxarsone (ROX) in industrial production leads to harmful effects on water, soil, food, and living creatures. It is significant to detect its concentration in the environment and biosystem. Herein, two aggregation-induced emission (AIE)-active fluorescence probes, TPE-TPE and TPE-TPE-CN, are successfully synthesized via a sulfur(Ⅵ) fluoride exchange (SuFEx) click reaction and first employed to detect ROX in the environment and living 3T3 cells. These two probes can selectively detect ROX in water due to the synergistic effect of photoinduced electron transfer (PET) and fluorescence resonance energy transfer (FRET) between the probes and ROX. The detection limit of TPE-TPE and TPE-TPE-CN is 0.154 and 0.385 µmol/L, respectively, much lower than the safety concentration stipulated by the World Health Organization (WHO). In addition, with the aid of a color discrimination application in a smartphone, these two probes can also detect ROX in real samples (such as water, soil, and cabbage), demonstrating their excellent potential for monitoring ROX in a practical environment.
- Aggregation-induced emission,
- SuFEx,
- ROX,
- Fluorescent detection,
- Living cells
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