Citation: Shaojie Deng, Peihua Ma, Qinghong Bai, Xin Xiao. The transformation of nor-seco-cucurbit[10]uril to cucurbit[5]uril and cucurbit[8]uril controlled by its own concentration[J]. Chinese Chemical Letters, ;2025, 36(2): 109878. doi: 10.1016/j.cclet.2024.109878 shu

The transformation of nor-seco-cucurbit[10]uril to cucurbit[5]uril and cucurbit[8]uril controlled by its own concentration

Key Laboratory of Macrocyclic and Supramolecular Chemistry of Guizhou Province, Department of Chemistry, Guizhou University, Guiyang 550025, China

phma@gzu.edu.cn

gyhxxiaoxin@163.com

Received Date: 12 January 2024
Revised Date: 26 March 2024
Accepted Date: 9 April 2024
Available Online: 9 April 2024

Figures(5)

Nor-seco-cucurbit[10]uril (ns-CB[10]) is a kinetic product with unique structure. The single bridged methylene in its structure makes the molecular cavity of ns-CB[10] more deformable when compared to ordinary cucurbit[n]uril, reducing its structural stability. Repeated experiments showed that ns-CB[10] gradually cracks in an acidic solution and changes the specificity of cucurbit[5]uril (CB[5]) and cucurbit[8]uril (CB[8]) under more robust acidic solutions and when heated. A series of experiments were designed to study the transformation behavior of ns-CB[10]. It was found that the concentration of ns-CB[10] was correlated with the content distribution of CB[5] and CB[8]. This study explores the influencing factors and mechanisms of the transformation of ns-CB[10] to CB[5] and CB[8]. The results are of great significance for the application of ns-CB[10], understanding the formation mechanism of cucurbit[n]urils. Furthermore, it provides a new pathway for synthesizing new cucurbit[n]urils.
- Nor-seco-cucurbit[10]uril,
- Cracking,
- Transformation,
- Concentration control,
- Mechanism
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