Citation: Tengteng Wang, Yiming Ju, Yao Cheng, Haiyang Wang, Dejin Zang. Recent advances in polyoxometalates based strategies for green synthesis of drugs[J]. Chinese Chemical Letters, ;2025, 36(5): 109871. doi: 10.1016/j.cclet.2024.109871 shu

Recent advances in polyoxometalates based strategies for green synthesis of drugs

School of Pharmacy and Pharmaceutical Sciences & Institute of Materia Medica, State Key Laboratory of Advanced Drug Delivery and Release Systems, Shandong First Medical University & Shandong Academy of Medical Sciences, NHC Key Laboratory of Biotechnology Drugs (Shandong Academy of Medical Sciences), Key Lab for Rare & Uncommon Diseases of Shandong Province, Ji’nan 250117, China

wanghaiyang@sdfmu.edu.cn

zangdejin_lm@163.com

Received Date: 15 February 2024
Revised Date: 19 March 2024
Accepted Date: 8 April 2024
Available Online: 9 April 2024

Figures(10)

Green synthesis of drugs is of paramount importance for current public health and a prerequisite to new drugs exploiting. Nowadays, novel strategies of disease diagnosis and therapies are in blooming development as remarkable advances have been achieved which are all highly depended on drug development. Under the current requirements to high production capacity and novel synthesis methods of drugs, green synthesis based on strategies with different ways of empowering, advanced catalysts and unique reaction equipment are attracting huge attention and of great challenging. Higher quality products and environmentally friendly synthesis conditions are becoming more and more important for manufacturing process which has new requirements for catalyst materials and synthesis processes. Polyoxometalates (POMs) are class of transition metals-oxygen clusters with precise molecular structures and superior physicochemical properties which have made longstanding and important applications upon research community of functional materials, catalysis and medicine. In this review, the recent advances of polyoxometalates based strategies for green synthesis of drugs are summarized including POMs based catalysts, alternative reaction equipment based novel synthesis protocols. The significance of POMs to pharmaceutical and industrial field is highlighted and the related perspective for future development are well discussed.
- Polyoxometalates,
- Drug synthesis,
- Green catalysis,
- Healthcare,
- Medicine manufacture
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沈阳化工大学材料科学与工程学院沈阳 110142