Citation: Manoj Kumar Sarangi, L․D Patel, Goutam Rath, Sitansu Sekhar Nanda, Dong Kee Yi. Metal organic framework modulated nanozymes tailored with their biomedical approaches[J]. Chinese Chemical Letters, ;2024, 35(11): 109381. doi: 10.1016/j.cclet.2023.109381 shu

Metal organic framework modulated nanozymes tailored with their biomedical approaches

a.
Department of Pharmaceutics, Amity Institute of Pharmacy, Amity University, Lucknow 201313, India
b.
Department of Pharmaceutics, Parul Institute of Pharmacy, Parul University, Vadodara 391760, India
c.
Department of Pharmaceutics, School of Pharmaceutical Sciences, Siksha ’O’ Anusandhan University, Bhubaneswar 751030, India
d.
Department of Chemistry, Myongji University, Yongin 03674, Republic of Korea

manojsarangi2007@rediffmail.com

Received Date: 28 August 2023
Revised Date: 29 November 2023
Accepted Date: 4 December 2023
Available Online: 12 December 2023

Figures(3)

Nanozymes are the paradigm for bridging inorganic nanomaterials with biology and environment for taking the spontaneous responsibilities to outplay natural enzymes. Metal-organic frameworks (MOFs) are mesoporous materials of inorganic-organic coordination, bearing ampoules of active/target sites and having the tendency to mimic natural enzymes. Thus MOF-based nanozymes (NZs) could be recognized for their tremendous potential for bio-catalysis. However, MOFs are of four types namely: modified MOFs, pristine MOFs, MOF-derived materials and MOFs comprised of natural enzymes. The MOFs-based NZ modulated via ultrasound, light, and heat revealed diversified applications. This article is concentrated on different methods for the preparation of MOF-based NZ for mimicking the responses of catalases, multi-functional enzymes, oxidases, superoxide dismutase, hydrolases, and peroxidases, progress and challenges of MOFs/MOF-based materials for exploiting their recent and futuristic approaches in biomedical sector.
- MOF,
- Nanozyme,
- Catalysis,
- Biomedicine,
- Theranostics
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沈阳化工大学材料科学与工程学院沈阳 110142