Citation: Chang Xu, Zhize Liu, Xi Chen, Yang Gao, Wenjun Wang, Xijing Zhuang, Hao Zhang, Xufeng Dong. Bone tissue engineering scaffold materials: Fundamentals, advances, and challenges[J]. Chinese Chemical Letters, ;2024, 35(2): 109197. doi: 10.1016/j.cclet.2023.109197 shu

Bone tissue engineering scaffold materials: Fundamentals, advances, and challenges

Chang Xu ^{a, b} ,
Zhize Liu ^c ,
Xi Chen ^d ,
Yang Gao ^a ,
Wenjun Wang ^a ,
Xijing Zhuang ^{a, *,} ,
Hao Zhang ^c ,
Xufeng Dong ^{b, *,}

a.
Department of Cardiovascular Surgery, Central Hospital of Dalian University of Technology, Dalian 116089, China
b.
School of Materials Science and Engineering, Dalian University of Technology, Dalian 116024, China
c.
Department of Orthopaedics, Central Hospital of Dalian University of Technology, Dalian 116089, China
d.
Department of Dermatology, Allergology, and Venereology, University of Lübeck, Lübeck 23562, Germany

dlmchcsd@126.com

dongxf@dlut.edu.cn

Received Date: 15 August 2023
Revised Date: 8 October 2023
Accepted Date: 10 October 2023
Available Online: 14 October 2023

Figures(10)

Bone damage caused by trauma and tumors is a serious problem for human health, therefore, three-dimensional (3D) scaffolding materials that stimulate and promote the regeneration of broken bone tissues have become the focus of current research in the field of bone damage repair. To this regard, a preferential combination of materials and preparation techniques is considered crucial for the preparation of advanced bone tissue engineering scaffolds to better facilitate the regeneration of broken bone. In this review, current research advances and challenges in bone tissue engineering scaffolds are discussed and analyzed in detail. First, we elucidated the structure and self-healing mechanism of bone tissue. Subsequently, the main applications of different materials, including inorganic and organic materials, in bone tissue engineering scaffolds are summarized. Moreover, we overview the latest research progress of the mainstream preparation strategies of bone tissue engineering scaffolds, and provide an in-depth analysis of the different advantages of each method. Finally, promising future directions and challenges of bone tissue engineering scaffolds are systematically discussed.
- Biomaterials,
- Bone defects,
- Tissue engineering,
- Scaffolds,
- Osteogenesis
1. [1]
  D.C. Wascher, L. Bulthuis, Curr. Rev. Musculoskelet. Med. 7 (2014) 387–393. doi: 10.1007/s12178-014-9242-y
2. [2]
  Z. Xu, Z. Zhu, H. Chen, et al., Biomaterials 282 (2022) 121390. doi: 10.1016/j.biomaterials.2022.121390
3. [3]
  C. Xu, Y. Kang, S. Guan, et al., Chin. Chem. Lett. 34 (2023) 107825. doi: 10.1016/j.cclet.2022.107825
4. [4]
  K. Huang, G. Liu, Z. Gu, et al., Chin. Chem. Lett. 31 (2020) 3190–3194. doi: 10.1016/j.cclet.2020.07.002
5. [5]
  A.Y. Rioja, E.L.H. Daley, J.C. Habif, et al., Acta Biomater. 55 (2017) 144–152. doi: 10.1016/j.actbio.2017.03.050
6. [6]
  Y. Kang, C. Xu, L. Meng, et al., Bioact. Mater. 18 (2022) 26–41.
7. [7]
  N. Xue, X. Ding, R. Huang, et al., Pharmaceuticals 15 (2022) 879. doi: 10.3390/ph15070879
8. [8]
  J.F. Keating, A.H.R.W. Simpson, C.M. Robinson, J. Bone Joint Surg. Br. 87 (2005) 142–150.
9. [9]
  O. Faour, R. Dimitriou, C.A. Cousins, et al., Injury 42 (2011) S87–S90. doi: 10.1016/j.injury.2011.06.020
10. [10]
  L. Wang, Y. Wu, T. Hu, et al., Acta Biomater. 96 (2019) 175–187. doi: 10.1016/j.actbio.2019.06.035
11. [11]
  Q. Wang, J. Xu, H. Jin, et al., Chin. Chem. Lett. 28 (2017) 1801–1807. doi: 10.1016/j.cclet.2017.07.011
12. [12]
  M.N. Collins, G. Ren, K. Young, et al., Adv. Funct. Mater. 31 (2021) 2010609. doi: 10.1002/adfm.202010609
13. [13]
  G. Turnbull, J. Clarke, F. Picard, et al., Bioact. Mater. 3 (2018) 278–314.
14. [14]
  S. Anjum, F. Rahman, P. Pandey, et al., Int. J. Mol. Sci. 23 (2022) 9206. doi: 10.3390/ijms23169206
15. [15]
  H. Qu, H. Fu, Z. Han, et al., RSC Adv. 9 (2019) 26252–26262. doi: 10.1039/C9RA05214C
16. [16]
  L. Huang, J. Zhang, X. Liu, et al., Chin. Chem. Lett. 32 (2021) 234–238. doi: 10.1016/j.cclet.2020.11.046
17. [17]
  X. Liu, P. Ma, Ann. Biomed. Eng. 32 (2004) 477–486. doi: 10.1023/B:ABME.0000017544.36001.8e
18. [18]
  A.R. Shrivats, M.C. McDermott, J.O. Hollinger, Drug Discov. Today 19 (2014) 781–786. doi: 10.1016/j.drudis.2014.04.010
19. [19]
  F. Pati, T. Song, G. Rijal, et al., Biomaterials 37 (2015) 230–241. doi: 10.1016/j.biomaterials.2014.10.012
20. [20]
  F. Zhang, M.W. King, Adv. Healthc. Mater. 9 (2020) e1901358. doi: 10.1002/adhm.201901358
21. [21]
  L. Cui, J. Zhang, J. Zou, et al., Biomaterials 230 (2020) 119617. doi: 10.1016/j.biomaterials.2019.119617
22. [22]
  T. Zhu, Y. Cui, M. Zhang, et al., Bioact. Mater. 5 (2020) 584–601.
23. [23]
  M. Yi, Y. Nie, C. Zhang, et al., J. Immunol. Res. 2022 (2022) 4450196.
24. [24]
  C. Xu, Y. Kang, X. Dong, et al., Chin. Chem. Lett. 34 (2023) 107528. doi: 10.1016/j.cclet.2022.05.042
25. [25]
  L. Roseti, V. Parisi, M. Petretta, et al., Mater. Sci. Eng. C 78 (2017) 1246–1262. doi: 10.1016/j.msec.2017.05.017
26. [26]
  R. Wang, M. Wang, R. Jin, et al., Adv. Sci. 10 (2023) e2207698. doi: 10.1002/advs.202207698
27. [27]
  Ž. Perić Kačarević, P. Rider, S. Alkildani, et al., Int. J. Artif. Organs. 43 (2019) 69–86.
28. [28]
  M.M. Martino, P.S. Briquez, E. Guc, et al., Science 343 (2014) 885–888. doi: 10.1126/science.1247663
29. [29]
  M.A. Woodruff, C. Lange, J. Reichert, et al., Mater. Today 15 (2012) 430–435. doi: 10.1016/S1369-7021(12)70194-3
30. [30]
  C. Barberio, J. Saez, A. Withers, et al., Adv. Healthc. Mater. 11 (2022) e2200941. doi: 10.1002/adhm.202200941
31. [31]
  T.M. Koushik, C.M. Miller, E. Antunes, Adv. Healthc. Mater. 12 (2023) e2202766. doi: 10.1002/adhm.202202766
32. [32]
  U.G.K. Wegst, H. Bai, E. Saiz, et al., Nat. Mater. 14 (2014) 23–36.
33. [33]
  V.S. Kattimani, S. Kondaka, K.P. Lingamaneni, Bone Tissue Regen. Insights 7 (2016) BTRI.S36138. doi: 10.4137/BTRI.S36138
34. [34]
  V. Ebacher, R.Z. Wang, Adv. Funct. Mater. 19 (2009) 57–66. doi: 10.1002/adfm.200801234
35. [35]
  N.G. Sahoo, Y. Pan, L. Li, et al., Nanomedicine 8 (2013) 639–653. doi: 10.2217/nnm.13.44
36. [36]
  X. Wang, S. Xu, S. Zhou, et al., Biomaterials 83 (2016) 127–141. doi: 10.1016/j.biomaterials.2016.01.012
37. [37]
  J.D. Currey, Osteoporos. Int. 14 (2003) S29–S36. doi: 10.1007/s00198-003-1470-8
38. [38]
  A.I. Alford, K.M. Kozloff, K.D. Hankenson, Int. J. Biochem. Cell Biol. 65 (2015) 20–31. doi: 10.1016/j.biocel.2015.05.008
39. [39]
  P. Chocholata, V. Kulda, V. Babuska, Materials 12 (2019) 568. doi: 10.3390/ma12040568
40. [40]
  S. Bose, S. Vahabzadeh, A. Bandyopadhyay, Mater. Today 16 (2013) 496–504. doi: 10.1016/j.mattod.2013.11.017
41. [41]
  T. Bai, K. Zhao, Z. Lu, et al., Chin. Chem. Lett. 32 (2021) 1051–1054. doi: 10.1016/j.cclet.2020.07.034
42. [42]
  M. Keeney, J.J. van den Beucken, P.M. van der Kraan, et al., Biomaterials 31 (2010) 2893–2902. doi: 10.1016/j.biomaterials.2009.12.041
43. [43]
  F. Diomede, G.D. Marconi, L. Fonticoli, et al., Int. J. Mol. Sci. 21 (2020) 3242. doi: 10.3390/ijms21093242
44. [44]
  G.L. Koons, M. Diba, A.G. Mikos, Nat. Rev. Mater. 5 (2020) 584–603. doi: 10.1038/s41578-020-0204-2
45. [45]
  X. Hao, X. Zhang, Y. Hu, et al., Chin. Chem. Lett. 34 (2023) 107965. doi: 10.1016/j.cclet.2022.107965
46. [46]
  S. Cao, Y. Zhao, Y. Hu, et al., Compos. Part B: Eng. 202 (2020) 108445. doi: 10.1016/j.compositesb.2020.108445
47. [47]
  Q. Zhang, K. Huang, J. Tan, et al., Chin. Chem. Lett. 33 (2022) 1623–1626. doi: 10.1016/j.cclet.2021.09.105
48. [48]
  P. Feng, P. Wu, C. Gao, et al., Adv. Sci. 5 (2018) 1700817. doi: 10.1002/advs.201700817
49. [49]
  C.E. Wen, Y. Yamada, K. Shimojima, et al., J. Mater. Res. Technol. 17 (2002) 2633–2639. doi: 10.1557/JMR.2002.0382
50. [50]
  M.A. Lopez-Heredia, J. Sohier, C. Gaillard, et al., Biomaterials 29 (2008) 2608–2615. doi: 10.1016/j.biomaterials.2008.02.021
51. [51]
  M. Yazdimamaghani, M. Razavi, D. Vashaee, et al., Mater. Sci. Eng. C 71 (2017) 1253–1266. doi: 10.1016/j.msec.2016.11.027
52. [52]
  J. Ballarre, R. Seltzer, E. Mendoza, et al., Mater. Sci. Eng. C 31 (2011) 545–552. doi: 10.1016/j.msec.2010.11.030
53. [53]
  D.H. Lee, N. Tripathy, J.H. Shin, et al., Int. J. Biol. Macromol. 95 (2017) 14–23. doi: 10.1016/j.ijbiomac.2016.11.002
54. [54]
  S. Deville, E. Saiz, A.P. Tomsia, Biomaterials 27 (2006) 5480–5489. doi: 10.1016/j.biomaterials.2006.06.028
55. [55]
  T. Reiter, T. Panick, K. Schuhladen, Bioact. Mater. 4 (2018) 1–7.
56. [56]
  E.B. Toloue, S. Karbasi, H. Salehi, et al., Mater. Sci. Eng. C 99 (2019) 1075–1091. doi: 10.1016/j.msec.2019.02.062.022
57. [57]
  S. Pieralli, R.J. Kohal, R.E. Jung, et al., J. Dent. Res. 96 (2017) 38–46. doi: 10.1177/0022034516664043
58. [58]
  W. Weng, W. Wu, M. Hou, et al., J. Mater. Sci. 56 (2021) 8309–8333. doi: 10.1007/s10853-021-05824-2
59. [59]
  K. Sakthiabirami, J. Kang, J. Jang, et al., Mater. Sci. Eng. C 123 (2021) 111950. doi: 10.1016/j.msec.2021.111950
60. [60]
  C. Meng, D. Tang, X. Liu, et al., Int. J. Biol. Macromol. 235 (2023) 123781. doi: 10.1016/j.ijbiomac.2023.123781
61. [61]
  J. Ju, X. Peng, K. Huang, et al., Polymer 180 (2019) 121707. doi: 10.1016/j.polymer.2019.121707
62. [62]
  X. Hu, W. Zhao, Z. Zhang, et al., Chin. Chem. Lett. 34 (2023) 107451. doi: 10.1016/j.cclet.2022.04.049
63. [63]
  H. Wang, E. Wang, Y. Huang, et al., J. Appl. Polym. Sci. 137 (2020) e49571. doi: 10.1002/app.49571
64. [64]
  B. Felice, M.A. Sanchez, M.C. Socci, et al., Mater. Sci. Eng. C 93 (2018) 724–738. doi: 10.1016/j.msec.2018.08.009
65. [65]
  M. Khalili, H. Keshvari, R. Imani, et al., Polym. Adv. Technol. 33 (2022) 782–794. doi: 10.1002/pat.5555
66. [66]
  X. Liang, P. Duan, J. Gao, et al., ACS Biomater. Sci. Eng. 4 (2018) 3506–3521. doi: 10.1021/acsbiomaterials.8b00552
67. [67]
  Z. Ma, Q. Wang, W. Xie, et al., Polym. Compos. 42 (2021) 3593–3602. doi: 10.1002/pc.26081
68. [68]
  W. Huang, X. Shi, L. Ren, et al., Biomaterials 31 (2010) 4278–4285. doi: 10.1016/j.biomaterials.2010.01.059
69. [69]
  B. Ashwin, B. Abinaya, T.P. Prasith, et al., Int. J. Biol. Macromol. 162 (2020) 523–532. doi: 10.1016/j.ijbiomac.2020.06.157
70. [70]
  D. Atila, A. Karatas, A. Evcin, et al., Cellulose 26 (2019) 9765–9785. doi: 10.1007/s10570-019-02741-1
71. [71]
  X. Hu, Z. Zhang, H. Wu, et al., Biomater. Adv. 152 (2023) 213501. doi: 10.1016/j.bioadv.2023.213501
72. [72]
  B. Nasri-Nasrabadi, A. Kaynak, P. Heidarian, et al., Polym. Adv. Technol. 29 (2018) 2553–2559. doi: 10.1002/pat.4367
73. [73]
  Y. Zhu, L. Kong, F. Farhadi, et al., Biomaterials 192 (2019) 149–158. doi: 10.1016/j.biomaterials.2018.11.017
74. [74]
  S. Saravanan, R.S. Leena, N. Selvamurugan, Int. J. Biol. Macromol. 93 (2016) 1354–1365. doi: 10.1016/j.ijbiomac.2016.01.112
75. [75]
  T. Li, Y. Zhang, H. Ren, et al., Carbohydr. Polym. 260 (2021) 117765. doi: 10.1016/j.carbpol.2021.117765
76. [76]
  D. Atila, D. Keskin, A. Tezcaner, Mater. Sci. Eng. C 69 (2016) 1103–1115. doi: 10.1016/j.msec.2016.08.015
77. [77]
  A. Zheng, L. Cao, Y. Liu, et al., Carbohydr. Polym. 199 (2018) 244–255. doi: 10.1016/j.carbpol.2018.06.093
78. [78]
  Z. Li, T. Du, C. Ruan, et al., Bioact. Mater. 6 (2021) 1491–1511.
79. [79]
  Y. Xie, K. Lee, X. Wang, et al., J. Mater. Chem. B 9 (2021) 8491–8500. doi: 10.1039/D1TB01559A
80. [80]
  Y. Huang, X. Yu, L. He, et al., Chin. Chem. Lett. 31 (2020) 1797–1800. doi: 10.1016/j.cclet.2020.01.039
81. [81]
  F. Xue, J. Cornelissen, Q. Yuan, et al., Chin. Chem. Lett. 34 (2023) 107448. doi: 10.1016/j.cclet.2022.04.046
82. [82]
  Z. Du, H. Leng, L. Guo, et al., Compos. Part B: Eng. 190 (2020) 107937. doi: 10.1016/j.compositesb.2020.107937
83. [83]
  A. Farzin, S. Hassan, S. Ebrahimi-Barough, et al., Mater. Sci. Eng. C 105 (2019) 110009. doi: 10.1016/j.msec.2019.110009
84. [84]
  H. Wu, R. Zhang, B. Hu, et al., Chin. Chem. Lett. 32 (2021) 3940–3947. doi: 10.1016/j.cclet.2021.04.043
85. [85]
  A.G. Mikos, S.W. Herring, P. Ochareon, et al., Tissue Eng. 12 (2006) 3307–3309. doi: 10.1089/ten.2006.12.3307
86. [86]
  E.A. Abou Neel, W. Chrzanowski, V.M. Salih, et al., J. Den. 42 (2014) 915–928. doi: 10.1016/j.jdent.2014.05.008
87. [87]
  G. Bouet, D. Marchat, M. Cruel, et al., Tissue Eng. Part B: Rev. 21 (2015) 133–156.
88. [88]
  H. Li, H. Li, B. Wang, et al., Chin. Chem. Lett. 25 (2014) 1635–1638. doi: 10.1016/j.cclet.2014.06.019
89. [89]
  C.M. Murphy, M.G. Haugh, F.J. O'Brien, Biomaterials 31 (2010) 461–466. doi: 10.1016/j.biomaterials.2009.09.063
90. [90]
  K. Huang, J. Huang, J. Zhao, et al., Chin. Chem. Lett. 33 (2022) 1941-1845. doi: 10.1016/j.cclet.2021.10.073
91. [91]
  W. Xu, J. Tian, Z. Liu, et al., Mater. Sci. Eng. C 105 (2019) 110015. doi: 10.1016/j.msec.2019.110015
92. [92]
  S. Wang, L. Liu, K. Li, et al., Mater. Des. 168 (2019) 107643. doi: 10.1016/j.matdes.2019.107643
93. [93]
  W. Xu, X. Lu, M.D. Hayat, et al., J. Mater. Res. Technol. 8 (2019) 3696–3704. doi: 10.1016/j.jmrt.2019.06.021
94. [94]
  J.W. Lee, H. Han, K. Han, et al., Proc. Natl. Acad. Sci. U. S. A. 113 (2016) 716–721. doi: 10.1073/pnas.1518238113
95. [95]
  S. Kamrani, C. Fleck, Biometals 32 (2019) 185–193. doi: 10.1007/s10534-019-00170-y
96. [96]
  F. Witte, V. Kaese, H. Haferkamp, et al., Biomaterials 26 (2005) 3557–3563. doi: 10.1016/j.biomaterials.2004.09.049
97. [97]
  D. Zhao, S. Huang, F. Lu, et al., Biomaterials 81 (2016) 84–92. doi: 10.1016/j.biomaterials.2015.11.038
98. [98]
  L. Chen, Z. Lin, M. Wang, et al., J. Orthop. Transl. 17 (2019) 133–137.
99. [99]
  J. Brandaoneto, V. Stefan, B.B. Mendonca, et al., Nutr. Res. 15 (1995) 335–358. doi: 10.1016/0271-5317(95)00003-8
100. [100]
  M. Nagata, B. Lonnerdal, J. Nutr. Biochem. 22 (2011) 172–178. doi: 10.1016/j.jnutbio.2010.01.003
101. [101]
  S. Zhang, J. Li, Y. Song, et al., Mater. Sci. Eng. C 29 (2009) 1907–1912. doi: 10.1016/j.msec.2009.03.001
102. [102]
  Y. He, H. Tao, Y. Zhang, et al., Chin. Sci. Bull. 54 (2009) 484–491.
103. [103]
  J. Yu, L. Xu, K. Li, et al., Sci. Rep. 7 (2017) 3440. doi: 10.1038/s41598-017-03661-5
104. [104]
  H. Pan, H. Gao, Q. Li, et al., J. Mater. Chem. B 8 (2020) 6100–6114. doi: 10.1039/D0TB00901F
105. [105]
  H. Ma, C. Feng, J. Chang, et al., Acta Biomater 79 (2018) 37–59. doi: 10.1016/j.actbio.2018.08.026
106. [106]
  Y. Huang, C. Wu, X. Zhang, et al., Acta Biomater 66 (2018) 81–92. doi: 10.1016/j.actbio.2017.08.044
107. [107]
  T. Li, B. Ma, J. Xue, et al., Adv. Healthc. Mater. 9 (2020) e1901211. doi: 10.1002/adhm.201901211
108. [108]
  A. Vezenkova, J. Locs. Bioact. Mater. 17 (2022) 109–124.
109. [109]
  L. Zhang, G. Yang, B. Johnson, et al., Acta Biomater 84 (2019) 16–33. doi: 10.1016/j.actbio.2018.11.039
110. [110]
  K. Zhou, P. Yu, X. Shi, et al., ACS Nano 13 (2019) 9595–9606. doi: 10.1021/acsnano.9b04723
111. [111]
  A. Kakuta, T. Tanaka, M. Chazono, et al., Biomater. Res. 23 (2019) 12. doi: 10.1186/s40824-019-0161-2
112. [112]
  K.E.G. Dienel, B. van Bochove, J.V. Seppala, Biomacromolecules 21 (2020) 366–375. doi: 10.1021/acs.biomac.9b01272
113. [113]
  H. Ren, Y. Cui, A. Li, et al., Chin. Chem. Lett. 29 (2018) 395–398. doi: 10.1016/j.cclet.2018.01.023
114. [114]
  L.L. Hench, J.M. Polak, Science 295 (2002) 1014–1017. doi: 10.1126/science.1067404
115. [115]
  W. Xiao, M.A. Zaeem, G. Li, et al., J. Mater. Sci. 52 (2017) 9039–9054. doi: 10.1007/s10853-017-0777-3
116. [116]
  L. Wu, X. Shi, Z. Wu, Adv. Funct. Mater. 33 (2023) 2211454. doi: 10.1002/adfm.202211454
117. [117]
  Z. Bao, C. Xian, Q. Yuan, et al., Adv. Healthc. Mater. 8 (2019) e1900670. doi: 10.1002/adhm.201900670
118. [118]
  L. Wang, L. Chen, J. Wang, et al., Chin. Chem. Lett. 33 (2022) 1956–1962. doi: 10.1016/j.cclet.2021.10.070
119. [119]
  P. Ruschhaupt, A. Varzi, S. Passerini, ChemSusChem 13 (2020) 763–770. doi: 10.1002/cssc.201902863
120. [120]
  Y. Li, X. Wang, Y. Wei, et al., Chin. Chem. Lett. 28 (2017) 2053–2057. doi: 10.1016/j.cclet.2017.09.004
121. [121]
  M.L. Becker, J.A. Burdick, Chem. Rev. 121 (2021) 10789–10791. doi: 10.1021/acs.chemrev.1c00354
122. [122]
  Z. Zhao, X. Fan, S. Wang, et al., Chin. Chem. Lett. 34 (2023) 107892. doi: 10.1016/j.cclet.2022.107892
123. [123]
  D. Liu, M. Nikoo, G. Boran, et al., Annu. Rev. Food Sci. Technol. 6 (2015) 527–557. doi: 10.1146/annurev-food-031414-111800
124. [124]
  M.F. Abazari, F. Soleimanifar, M. Amini Faskhodi, et al., J. Cell. Physiol. 235 (2020) 1155–1164. doi: 10.1002/jcp.29029
125. [125]
  R. Ashraf, H.S. Sofi, M.A. Beigh, et al., Adv. Exp. Med. Biol. 1077 (2018) 501–525.
126. [126]
  J.X. Yap, C.P. Leo, N.H.M. Yasin, et al., Bioengineered 13 (2022) 2226–2247. doi: 10.1080/21655979.2021.2024322
127. [127]
  Y. Chen, N. Kawazoe, G. Chen, Acta Biomater 67 (2018) 341–353. doi: 10.1016/j.actbio.2017.12.004
128. [128]
  C. Xu, Z. Wei, H. Gao, et al., Adv. Sci. 4 (2017) 1600410. doi: 10.1002/advs.201600410
129. [129]
  F. Zhang, Y. Xie, H. Celik, et al., Biofabrication 11 (2019) 035020. doi: 10.1088/1758-5090/ab15ce
130. [130]
  M. Younesi, A. Islam, V. Kishore, et al., Adv. Funct. Mater. 24 (2014) 5762–5770. doi: 10.1002/adfm.201400828
131. [131]
  H. Sun, J. Zhou, Z. Huang, et al., Int. J. Nanomed. 12 (2017) 3109–3120. doi: 10.2147/IJN.S128030
132. [132]
  S. Fu, P. Ni, B. Wang, et al., Biomaterials 33 (2012) 4801–4809. doi: 10.1016/j.biomaterials.2012.03.040
133. [133]
  S.E. Enderami, S.F. Ahmadi, R.N. Mansour, et al., Mater. Sci. Eng. C 108 (2020) 110398. doi: 10.1016/j.msec.2019.110398
134. [134]
  R. Zhang, Y. Zheng, T. Liu, Chin. Chem. Lett. 33 (2022) 1599–1603. doi: 10.1016/j.cclet.2021.09.018
135. [135]
  J.M. Gosline, P.A. Guerette, C.S. Ortlepp, et al., J. Exp. Biol. 202 (1999) 3295–3303. doi: 10.1242/jeb.202.23.3295
136. [136]
  Y. Wang, S. Zhang, J. Wang, Chin. Chem. Lett. 32 (2021) 1603–1614. doi: 10.1016/j.cclet.2020.11.073
137. [137]
  R. Li, G. Chen, X. Ma, et al., Chin. Chem. Lett. 22 (2011) 1107–1110. doi: 10.1016/j.cclet.2011.03.018
138. [138]
  J.H. Choi, D.K. Kim, J.E. Song, et al., Adv. Exp. Med. Biol. 1077 (2018) 371–387.
139. [139]
  G. Lai, K.T. Shalumon, S. Chen, et al., Carbohyd. Polym. 111 (2014) 288–297. doi: 10.1016/j.carbpol.2014.04.094
140. [140]
  J.Y. Kim, B. Yang, J.H. Ahn, et al., J. Adv. Prosthodont. 6 (2014) 539–546. doi: 10.4047/jap.2014.6.6.539
141. [141]
  Y.Y. Jo, S.G. Kim, K.J. Kwon, et al., Int. J. Mol. Sci. 18 (2017) 858. doi: 10.3390/ijms18040858
142. [142]
  L. Upadhyaya, J. Singh, V. Agarwal, et al., Carbohyd. Polym. 91 (2013) 452–466. doi: 10.1016/j.carbpol.2012.07.076
143. [143]
  R. Zhang, S. Chang, Y. Jing, et al., Carbohydr. Polym. 314 (2023) 120890. doi: 10.1016/j.carbpol.2023.120890
144. [144]
  F. Tao, Y. Cheng, X. Shi, et al., Carbohydr. Polym. 230 (2020) 115658. doi: 10.1016/j.carbpol.2019.115658
145. [145]
  L. Zheng, J. Zhu, Carbohydr. Polym. 54 (2003) 527–530. doi: 10.1016/j.carbpol.2003.07.009
146. [146]
  R.C. Goy, D. de Britto, O.B.G. Assis, Polimeros 19 (2009) 241–247. doi: 10.1590/S0104-14282009000300013
147. [147]
  K. Liu, X. Dong, Y. Wang, et al., Carbohydr. Polym. 298 (2022) 120047. doi: 10.1016/j.carbpol.2022.120047
148. [148]
  B. Maharjan, J. Park, V.K. Kaliannagounder, et al., Carbohydr. Polym. 251 (2021) 117023. doi: 10.1016/j.carbpol.2020.117023
149. [149]
  A.T.H. Wu, T. Aoki, M. Sakoda, et al., Biomacromolecules 16 (2015) 166–173. doi: 10.1021/bm501356c
150. [150]
  Z. Cao, Q. Li, G. Wang, Polym. Chem. 8 (2017) 6817–6823. doi: 10.1039/C7PY01153A
151. [151]
  U. Malik, Q. Duan, D. Niazi, Chin. Chem. Lett. 34 (2023) 108071. doi: 10.1016/j.cclet.2022.108071
152. [152]
  E.V. Vasconcelos, F.B. da Luz, S.P.A. da Paz, et al., J. Mater. Res. Technol. 23 (2023) 5923–5938. doi: 10.1016/j.jmrt.2023.02.171
153. [153]
  J.M. Miszuk, T. Xu, Q. Yao, et al., Appl. Mater. Today 10 (2018) 194–202. doi: 10.1016/j.apmt.2017.12.004
154. [154]
  S. Cheng, Y. Jin, N. Wang, et al., Adv. Mater. 29 (2017) 201700171.
155. [155]
  E. Llorens, S. Calderon, L.J. del Valle, et al., Mater. Sci. Eng. C 50 (2015) 74–84. doi: 10.1016/j.msec.2015.01.100
156. [156]
  Y. Dai, T. Lu, M. Shao, et al., Front. Bioeng. Biotechnol. 10 (2022) 1011783. doi: 10.3389/fbioe.2022.1011783
157. [157]
  F. Wu, C. Liu, B. O'Neill, et al., Appl. Surf. Sci. 258 (2012) 7589–7595. doi: 10.1016/j.apsusc.2012.04.094
158. [158]
  A. Asti, L. Gioglio, Int. J. Artif. Organs 37 (2014) 187–205. doi: 10.5301/ijao.5000307
159. [159]
  P. Grossen, D. Witzigmann, S. Sieber, et al., J. Control. Release 260 (2017) 46–60. doi: 10.1016/j.jconrel.2017.05.028
160. [160]
  T.K. Dash, V.B. Konkimalla, J. Control. Release 158 (2012) 15–33. doi: 10.1016/j.jconrel.2011.09.064
161. [161]
  T. Zhu, M. Jiang, M. Zhang, et al., Bioact. Mater. 9 (2022) 446–460.
162. [162]
  R.P.F. Lanao, A.M. Jonker, J.G.C. Wolke, et al., Tissue Eng. Part B: Rev. 19 (2013)380–390.
163. [163]
  F. Danhier, E. Ansorena, J.M. Silva, et al., J. Control. Release 161 (2012) 505–522. doi: 10.1016/j.jconrel.2012.01.043
164. [164]
  L. Wu, J. Ding, Biomaterials 25 (2004) 5821–5830. doi: 10.1016/j.biomaterials.2004.01.038
165. [165]
  A. Kumari, S.K. Yadav, S.C. Yadav, Colloid Surf. B 75 (2010) 1–18. doi: 10.1016/j.colsurfb.2009.09.001
166. [166]
  Y. Takeoka, M. Hayashi, N. Sugiyama, et al., Polym. J. 47 (2015) 164–170. doi: 10.1038/pj.2014.121
167. [167]
  G. Liu, T. Lu, X. Ji, et al., Chem. J. Chin. Univ. 40 (2019) 1552–1560.
168. [168]
  J. Zhang, D. Tong, H. Song, et al., Adv. Mater. 34 (2022) e2202044. doi: 10.1002/adma.202202044
169. [169]
  M.M. Stevens, Mater. Today 11 (2008) 18–25.
170. [170]
  X. Li, L. Wang, Y. Fan, et al., J. Biomed. Mater. Res. A 101 (2013) 2424–2435.
171. [171]
  N. Shadjou, M. Hasanzadeh, Mater. Sci. Eng. C 55 (2015) 401–409. doi: 10.1016/j.msec.2015.05.027
172. [172]
  S. Hao, J. Meng, Y. Zhang, et al., Biomaterials 140 (2017) 16–25. doi: 10.1016/j.biomaterials.2017.06.013
173. [173]
  D. Wu, X. Chang, J. Tian, et al., J. Nanobiotechnology 19 (2021) 209. doi: 10.1186/s12951-021-00958-6
174. [174]
  Y. Jia, P. Zhang, Y. Sun, et al., Nanomed. Nanotechnol. 21 (2019) 102040. doi: 10.1016/j.nano.2019.102040
175. [175]
  S. Hu, Y. Zhou, Y. Zhao, et al., J. Tissue Eng. Regen. Med. 12 (2018) e2085–e2098. doi: 10.1002/term.2641
176. [176]
  M. Rai, A. Yadav, A. Gade, Biotechnol. Adv. 27 (2009) 76–83. doi: 10.1016/j.biotechadv.2008.09.002
177. [177]
  Y.M.F. Chen, M. Guan, R.Y. Ren, et al., Int. J. Nanomed. 15 (2020) 2011–2026. doi: 10.2147/IJN.S242919
178. [178]
  D. Lee, D.N. Heo, H.R. Nah, et al., Int. J. Nanomed. 13 (2018) 7019–7031. doi: 10.2147/IJN.S185715
179. [179]
  R. Eivazzadeh-Keihan, A. Maleki, M. de la Guardia, et al., J. Adv. Res. 18 (2019) 185–201. doi: 10.1016/j.jare.2019.03.011
180. [180]
  G. Pagona, N. Tagmatarchis, Curr. Med. Chem. 13 (2006) 1789–1798. doi: 10.2174/092986706777452524
181. [181]
  B. Marrs, R. Andrews, T. Rantell, et al., J. Biomed. Mater. Res. A 77 (2006) 269–276.
182. [182]
  X. Li, H. Liu, X. Niu, et al., Biomaterials 33 (2012) 4818–4827. doi: 10.1016/j.biomaterials.2012.03.045
183. [183]
  P. Yu, R. Bao, X. Shi, et al., Carbohydr. Polym. 155 (2017) 507–515. doi: 10.1016/j.carbpol.2016.09.001
184. [184]
  S. Saravanan, A. Chawla, M. Vairamani, et al., Int. J. Biol. Macromol. 104 (2017) 1975–1985. doi: 10.1016/j.ijbiomac.2017.01.034
185. [185]
  C. Zhao, X. Lu, C. Zanden, et al., Biomed. Mater. 10 (2015) 015019. doi: 10.1088/1748-6041/10/1/015019
186. [186]
  X. Zhang, D. Zeng, N. Li, et al., Sci. Rep. 6 (2016) 19361. doi: 10.1038/srep19361
187. [187]
  Y. Cheng, D. Ramos, P. Lee, et al., J. Biomed. Nanotechnol. 10 (2014) 287–298. doi: 10.1166/jbn.2014.1753
188. [188]
  R.P. Pirraco, T. Iwata, T. Yoshida, et al., Lab. Invest. 94 (2014) 663–673. doi: 10.1038/labinvest.2014.55
189. [189]
  Q. Cheng, K. Rutledge, E. Jabbarzadeh, Ann. Biomed. Eng. 41 (2013) 904–916. doi: 10.1007/s10439-012-0728-8
190. [190]
  R. Rozylo, Trends Food Sci. Tech. 102 (2020) 39–50. doi: 10.1016/j.tifs.2020.06.005
191. [191]
  A. Merivaara, J. Zini, E. Koivunotko, et al., J. Control. Release 336 (2021) 480–498. doi: 10.1016/j.jconrel.2021.06.042
192. [192]
  R. Najjar, C. Stubenrauch, J. Colloid Inter. Sci. 331 (2009) 214–220. doi: 10.1016/j.jcis.2008.11.035
193. [193]
  M. Wang, B. Li, Y. Liu, et al., ACS Omega 6 (2021) 35727–35737. doi: 10.1021/acsomega.1c05623
194. [194]
  E. Kolanthai, P.A. Sindu, D.K. Khajuria, et al., ACS Appl. Mater. Interfaces 10 (2018) 12441–12452. doi: 10.1021/acsami.8b00699
195. [195]
  J.M. Holzwarth, P.X. Ma, Biomaterials 32 (2011) 9622–9629. doi: 10.1016/j.biomaterials.2011.09.009
196. [196]
  K. Qiu, B. Chen, W. Nie, et al., ACS Appl. Mater. Interfaces 8 (2016) 4137–4148. doi: 10.1021/acsami.5b11879
197. [197]
  Y. Zhang, Y. Chen, T. Ding, et al., NPJ Regen. Med. 8 (2023) 28. doi: 10.1038/s41536-023-00305-3
198. [198]
  T. Wu, M. Ding, C. Shi, et al., Chin. Chem. Lett. 31 (2020) 617–625. doi: 10.1016/j.cclet.2019.07.033
199. [199]
  I. Jun, H. Han, J.R. Edwards, et al., Int. J. Mol. Sci. 19 (2018) 745. doi: 10.3390/ijms19030745
200. [200]
  J. Wang, G. Wang, H. Shan, et al., Biomater. Sci. 7 (2019) 963–974. doi: 10.1039/C8BM01317A
201. [201]
  G.C. Rutledge, S.V. Fridrikh, Adv. Drug Deliv. Rev. 59 (2007) 1384–1391. doi: 10.1016/j.addr.2007.04.020
202. [202]
  Q. Yu, Y. Li, M. Wang, et al., Chin. Chem. Lett. 19 (2008) 223–226. doi: 10.1016/j.cclet.2007.12.005
203. [203]
  A. alogh, R. Cselkó, B. Démuth, et al., Int. J. Pharm. 495 (2015) 75–80. doi: 10.1016/j.ijpharm.2015.08.069
204. [204]
  A. Denchai, D. Tartarini, E. Mele, Front. Bioeng. Biotechnol. 6 (2018) 155. doi: 10.3389/fbioe.2018.00155
205. [205]
  J. Xie, M.R. Macewan, W.Z. Ray, et al., ACS Nano 4 (2010) 5027–5036. doi: 10.1021/nn101554u
206. [206]
  T. Xu, J.M. Miszuk, Y. Zhao, et al., Adv. Healthc. Mater. 4 (2015) 2238–2246. doi: 10.1002/adhm.201500345
207. [207]
  L. Li, G. Zhou, Y. Wang, et al., Biomaterials 37 (2015) 218–229. doi: 10.1016/j.biomaterials.2014.10.015
208. [208]
  Y. Zha, T. Lin, Y. Li, et al., Biomaterials 247 (2020) 119985. doi: 10.1016/j.biomaterials.2020.119985
209. [209]
  X. Wang, M. Jiang, Z. Zhou, et al., Compos. Part B: Eng. 110 (2017) 442–458. doi: 10.1016/j.compositesb.2016.11.034
210. [210]
  A. Zhang, F. Wang, L. Chen, et al., Chin. Chem. Lett. 32 (2021) 2923–2932. doi: 10.1016/j.cclet.2021.03.073
211. [211]
  P. Szymczyk-Ziółkowska, M.B. Łabowska, J. Detyna, et al., Biocybern. Biomed. Eng. 40 (2020) 624–638. doi: 10.1016/j.bbe.2020.01.015
212. [212]
  H. Zhou, H. Yang, S. Yao, et al., Chin. Chem. Lett. 33 (2022) 3681–3694. doi: 10.1016/j.cclet.2021.11.018
213. [213]
  X. Zhou, Y. Qian, L. Chen, et al., ACS Nano 17 (2023) 5140–5156. doi: 10.1021/acsnano.3c00598
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