Citation: Wen Chen, Kun Shi, Yan Yu, Peipei Yang, Zhongwu Bei, Dong Mo, Liping Yuan, Meng Pan, Yu Chen, Zhiyong Qian. Drug delivery systems for colorectal cancer chemotherapy[J]. Chinese Chemical Letters, ;2024, 35(2): 109159. doi: 10.1016/j.cclet.2023.109159 shu

Drug delivery systems for colorectal cancer chemotherapy

Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu 610041, China

anderson-qian@163.com

zhiyongqian@scu.edu.cn

Received Date: 19 July 2023
Revised Date: 26 September 2023
Accepted Date: 27 September 2023
Available Online: 29 September 2023

Figures(9)

Colorectal cancer causes the third most common type of malignant tumors with high morbidity and mortality. Chemotherapy is currently one of the most effective and common treatments for colorectal cancer. However, the poor water solubility of some chemotherapeutics, untargeted drug delivery, and the undesirable systemic side effects of conventional treatment remain the major issues for colorectal cancer chemotherapy. Fortunately, drug delivery systems (DDS) based on biomaterials have been widely investigated and found to be capable of resolving those issues with good performance. Therefore, the main goal of this review is to summarize and discuss the progress and potential advantages of different DDS for colorectal cancer chemotherapy. We not only reviewed the nanocarriers used to improve the solubility of chemotherapeutics, including liposomes, micelles, and nanoparticles, but also discussed targeted DDS based on specific ligand-receptor recognition and tumor microenvironmental stimulus responses. Furthermore, locally administered systems based on hydrogels and microspheres, which have been shown to increase drug accumulation at the tumor site while decreasing systemic toxicity, were also emphasized. DDS provides a good option for improving the efficacy of chemotherapy in the treatment of colorectal cancer.
- Colorectal cancer,
- Chemotherapy,
- Drug delivery systems,
- Solubility,
- Targeted,
- Local administration
1. [1]
  F. Bray, M. Laversanne, E. Weiderpass, I. Soerjomataram, Cancer 127 (2021) 3029–3030. doi: 10.1002/cncr.33587
2. [2]
  H. Sung, J. Ferlay, R.L. Siegel, et al., CA Cancer J. Clin. 71 (2021) 209–249. doi: 10.3322/caac.21660
3. [3]
  R.L. Siegel, K.D. Miller, A. Goding Sauer, et al., CA Cancer J. Clin. 70 (2020) 145–164. doi: 10.3322/caac.21601
4. [4]
  R.L. Siegel, N.S. Wagle, A. Cercek, R.A. Smith, A. Jemal, CA Cancer J. Clin. 73 (2023) 233–254. doi: 10.3322/caac.21772
5. [5]
  Nat. Rev. Dis. Primers 9 (2023) 22.
6. [6]
  M. Ponz de Leon, C. Di Gregorio, Dig. Liver Dis. 33 (2001) 372–388. doi: 10.1016/S1590-8658(01)80095-5nc.2020.01731
7. [7]
  D. Nassar, C. Blanpain, Annu. Rev. Pathol. 11 (2016) 47–76. doi: 10.1146/annurev-pathol-012615-044438
8. [8]
  B.K. Edwards, E. Ward, B.A. Kohler, et al., Cancer 116 (2010) 544–573. doi: 10.1002/cncr.247601002/adfm.202209405
9. [9]
  N. Li, B. Lu, C.Y. Luo, et al., Cancer Lett. 522 (2021) 255–268. doi: 10.1016/j.canlet.2021.09.034
10. [10]
  H.J. Wanebo, M. LeGolvan, P.B. Paty, et al., Clin. Exp. Metastasis 29 (2012) 821–839. doi: 10.1007/s10585-012-9517-x
11. [11]
  L. Bijelic, I. Ramos, D. Goere, Ann. Surg. Oncol. 28 (2021) 4140–4150. doi: 10.1245/s10434-021-10049-3
12. [12]
  N. Akhtar-Danesh, K. Logie, G.G. Akhtar-Danesh, C. Finley, Surg. Oncol. 35 (2020) 540–546. doi: 10.1016/j.suronc.2020.10.017
13. [13]
  M.M. Lange, C.J. van de Velde, Nat. Rev. Urol. 8 (2011) 51–57. doi: 10.1038/nrurol.2010.206
14. [14]
  L. Best, P. Simmonds, C. Baughan, et al., Cochrane Database Syst. Rev. 2000 (2000) CD001545.
15. [15]
  S. Gill, R.M. Goldberg, Drugs 64 (2004) 27–44.
16. [16]
  L. Leichman, J. Clin. Oncol. 24 (2006) 3817–3818. doi: 10.1200/JCO.2006.07.2546
17. [17]
  S. Bayraktar, U.D. Bayraktar, C.M. Rocha Lima, Clin. Colorectal Cancer 9 (2010) 144–149. doi: 10.3816/CCC.2010.n.019
18. [18]
  Y.H. Yun, B.K. Lee, K. Park, J. Control. Release 219 (2015) 2–7. doi: 10.1016/j.jconrel.2015.10.005
19. [19]
  A.M. Vargason, A.C. Anselmo, S. Mitragotri, Nat. Biomed. Eng. 5 (2021) 951–967. doi: 10.1038/s41551-021-00698-w
20. [20]
  T.Q. Wang, Y.A. Fu, S.J. Sun, et al., Chin. Chem. Lett. 34 (2023) 107508. doi: 10.1016/j.cclet.2022.05.022
21. [21]
  A. Dadwal, A. Baldi, R.K. Narang, Artif. Cells Nanomed. Biotechnol. 46 (2018) 295–305. doi: 10.1080/21691401.2018.1457039
22. [22]
  R. Liu, C. Luo, Z.Q. Pang, et al., Chin. Chem. Lett. 34 (2023) 107518. doi: 10.1016/j.cclet.2022.05.032
23. [23]
  Y.F. Yin, P.H. Sun, H.Q. Dong, et al., Chin. Chem. Lett. 34 (2023) 108594. doi: 10.1016/j.cclet.2023.108594
24. [24]
  J.M. Rabanel, V. Aoun, I. Elkin, M. Mokhtar, P. Hildgen, Curr. Med. Chem. 19 (2012) 3070–3102. doi: 10.2174/092986712800784702
25. [25]
  V. Ejigah, O. Owoseni, P. Bataille-Backer, et al., Polymers 14 (2022) 2601. doi: 10.3390/polym14132601
26. [26]
  D.A. Yardley, J. Control. Release 170 (2013) 365–372. doi: 10.1016/j.jconrel.2013.05.041
27. [27]
  H.Y. Lv, S. Ma, Z.B. Wang, et al., Chin. Chem. Lett. 32 (2021) 1765–1769. doi: 10.1016/j.cclet.2020.11.058
28. [28]
  Q. Li, J.B. Fan, H.K. Mu, et al., Chin. Chem. Lett. (2023), doi:10.1016/j.cclet.2023.108947. doi: 10.1016/j.cclet.2023.108947
29. [29]
  H.P. Hu, L.J. Yu, Z. Ding, et al., Chin. Chem. Lett. 34 (2023) 108592. doi: 10.1016/j.cclet.2023.108592
30. [30]
  S. Piawah, A.P. Venook, Cancer 125 (2019) 4139–4147. doi: 10.1002/cncr.32163
31. [31]
  A.R. Sousa, M.J. Oliveira, B. Sarmento, J. Pharmacol. Exp. Ther. 370 (2019) 657–670. doi: 10.1124/jpet.118.254441
32. [32]
  E. Pavitra, B. Dariya, G. Srivani, et al., Semin. Cancer Biol. 69 (2021) 293–306. doi: 10.1016/j.semcancer.2019.06.017
33. [33]
  T.J. Price, M. Tang, P. Gibbs, et al., Expert Rev. Anticancer Ther. 18 (2018) 991–1006. doi: 10.1080/14737140.2018.1502664
34. [34]
  R.H. Jin, Z.N. Liu, T. Liu, et al., Chin. Chem. Lett. 32 (2021) 3076–3082. doi: 10.1016/j.cclet.2021.03.084
35. [35]
  Y. Xiao, Y.H. Gu, L. Qin, et al., Colloids Surf. B 200 (2021) 111581. doi: 10.1016/j.colsurfb.2021.111581
36. [36]
  R. Tian, X.Y. Qiu, W.Y. Mu, et al., Chin. Chem. Lett. 35 (2024) 108343. doi: 10.1016/j.cclet.2023.108343
37. [37]
  Z.Y. Sun, C.J. Song, C. Wang, Y.Q. Hu, J.H. Wu, Mol. Pharm. 17 (2020) 373–391.
38. [38]
  R.C. Alves, R.P. Fernandes, J.O. Eloy, H.R.N. Salgado, M. Chorilli, Crit. Rev. Anal. Chem. 48 (2018) 110–118. doi: 10.1080/10408347.2017.1416283
39. [39]
  H. Gelderblom, J. Verweij, K. Nooter, A. Sparreboom, Eur. J. Cancer 37 (2001) 1590–1598. doi: 10.1016/S0959-8049(01)00171-X
40. [40]
  A.K. Singla, A. Garg, D. Aggarwal, Int. J. Pharm. 235 (2002) 179–192. doi: 10.1016/S0378-5173(01)00986-3
41. [41]
  M.R. Dreher, W. Liu, C.R. Michelich, et al., J. Natl. Cancer Inst. 98 (2006) 335–344. doi: 10.1093/jnci/djj070
42. [42]
  A.K. Iyer, G. Khaled, J. Fang, H. Maeda, Drug Discov. Today 11 (2006) 812–818. doi: 10.1016/j.drudis.2006.07.005
43. [43]
  Y. Panahi, M. Farshbaf, M. Mohammadhosseini, et al., Artif. Cells Nanomed. Biotechnol. 45 (2017) 788–799. doi: 10.1080/21691401.2017.1282496
44. [44]
  M.J. Mitchell, M.M. Billingsley, R.M. Haley, et al., Nat. Rev. Drug Discov. 20 (2021) 101–124. doi: 10.1038/s41573-020-0090-8
45. [45]
  G. Gregoriadis, E.J. Wills, C.P. Swain, A.S. Tavill, Lancet 1 (1974) 1313–1316.
46. [46]
  K. Sen, S. Banerjee, M. Mandal, Colloids Surf. B: Biointerfaces 180 (2019) 9–22. doi: 10.1016/j.colsurfb.2019.04.035
47. [47]
  Y.A. Li, H.L. Cong, S. Wang, B. Yu, Y.Q. Shen, Biomater. Sci. 8 (2020) 6442–6468. doi: 10.1039/D0BM01531H
48. [48]
  D. Guimaraes, A. Cavaco-Paulo, E. Nogueira, Int. J. Pharm. 601 (2021) 120571. doi: 10.1016/j.ijpharm.2021.120571
49. [49]
  L. Sercombe, T. Veerati, F. Moheimani, et al., Front. Pharmacol. 6 (2015) 286.
50. [50]
  J. Zhang, Y.Y. Pan, Q. Shi, et al., Cancer Commun. 42 (2022) 3–16. doi: 10.1002/cac2.12225
51. [51]
  B. Lv, H.Y. Zhang, China. Prac. Med. 5 (2010) 13–14. doi: 10.1186/1749-8546-5-13
52. [52]
  A.M. Saetern, M. Brandl, W.H. Bakkelund, B. Sveinbjørnsson, Anticancer. Drugs 15 (2004) 899–906. doi: 10.1097/00001813-200410000-00011
53. [53]
  H.K. Kimelberg, T.F. Tracy, S.M. Biddlecome, R.S. . Bourke, Cancer Res. 36 (1976) 2949 -2295.
54. [54]
  Y. Yoshizawa, Y. Kono, K. Ogawara, T. Kimura, K. Higaki, Int. J. Pharm. 412 (2011) 132–141. doi: 10.1016/j.ijpharm.2011.04.008
55. [55]
  D.S. Chow, L. Gong, M.D. Wolfe, B.C. Giovanella, Ann. N. Y. Acad. Sci. 922 (2000) 164–174. doi: 10.1111/j.1749-6632.2000.tb07034.x
56. [56]
  Z. Wang, G. Niu, X.Y. Chen, Pharm. Res. 31 (2014) 1358–1376. doi: 10.1007/s11095-013-1103-7
57. [57]
  S.R. Croy, G.S. Kwon, Curr. Pharm. Des. 12 (2006) 4669–4684. doi: 10.2174/138161206779026245
58. [58]
  R. Ideta, F. Tasaka, W.D. Jang, et al., Nano Lett. 5 (2005) 2426–2431. doi: 10.1021/nl051679d
59. [59]
  W.D. Jang, Y. Nakagishi, N. Nishiyama, et al., J. Control. Release 113 (2006) 73–79. doi: 10.1016/j.jconrel.2006.03.009
60. [60]
  R.D. Dabholkar, R.M. Sawant, D.A. Mongayt, P.V. Devarajan, V.P. Torchilin, Int. J. Pharm. 315 (2006) 148–157. doi: 10.1016/j.ijpharm.2006.02.018
61. [61]
  P. Opanasopit, M. Yokoyama, M. Watanabe, et al., Pharm. Res. 21 (2004) 2001–2008. doi: 10.1023/B:PHAM.0000048190.53439.eb
62. [62]
  K. Kawano, M. Watanabe, T. Yamamoto, et al., J. Control. Release 112 (2006) 329–332. doi: 10.1016/j.jconrel.2006.03.012
63. [63]
  A. Almeida, F. Castro, C. Resende, et al., J. Control. Release 349 (2022) 731–743. doi: 10.1016/j.jconrel.2022.07.029
64. [64]
  X. Gao, B.L. Wang, Q.J. Wu, et al., J. Biomed. Nanotechnol. 11 (2015) 578–589. doi: 10.1166/jbn.2015.1964
65. [65]
  H. Cho, G.S. Kwon, ACS Nano 5 (2011) 8721–8729. doi: 10.1021/nn202676u
66. [66]
  Y.L. Jang, U.J. Yun, M.S. Lee, et al., Int. J. Pharm. 434 (2012) 488–493. doi: 10.1016/j.ijpharm.2012.04.083
67. [67]
  J. Conniot, J.M. Silva, J.G. Fernandes, et al., Front. Chem. 2 (2014) 105.
68. [68]
  L.M. Mary Lazer, B. Sadhasivam, K. Palaniyandi, et al., Int. J. Biol. Macromol. 107 (2018) 1988–1998. doi: 10.1016/j.ijbiomac.2017.10.064
69. [69]
  K.T. Smitha, A. Anitha, T. Furuike, et al., Colloids Surf. B 104 (2013) 245–253. doi: 10.1016/j.colsurfb.2012.11.031
70. [70]
  S. Unal, Y. Aktas, J.M. Benito, E. Bilensoy, Int. J. Pharm. 584 (2020) 119468. doi: 10.1016/j.ijpharm.2020.119468
71. [71]
  N.M. Zaki, Drug Deliv. 21 (2014) 265–275. doi: 10.3109/10717544.2013.838808
72. [72]
  I. Ekladious, Y.L. Colson, M.W. Grinstaff, Nat. Rev. Drug Discov. 18 (2019) 273–294. doi: 10.1038/s41573-018-0005-0
73. [73]
  H. Zhang, H.X. Hu, H.R. Zhang, et al., Nanoscale 7 (2015) 10790–10800. doi: 10.1039/C4NR07450E
74. [74]
  R.I. El-Gogary, N. Rubio, J.T.W. Wang, et al., ASC Nano 2 (2014) 1384–1401.
75. [75]
  P.S. Giram, J.T. Wang, A.A. Walters, et al., Biomater. Sci. 9 (2021) 795–806. doi: 10.1039/D0BM01421D
76. [76]
  J.K. Lu, X.X. Chuan, H. Zhang, et al., Int. J. Pharm. 471 (2014) 525–535. doi: 10.1016/j.ijpharm.2014.05.032
77. [77]
  C.D. Phung, T.G. Le, V.H. Nguyen, et al., Pharm. Res. 37 (2020) 129. doi: 10.1007/s11095-020-02819-7
78. [78]
  D. Schmid, G.E. Jarvis, F. Fay, et al., Cell Death Dis. 5 (2014) e1454. doi: 10.1038/cddis.2014.413
79. [79]
  W.J. Wang, X.Y. He, X.J. Wang, et al., Chin. Chem. Lett. (2023), doi:10.1016/j.cclet.2023.108656. doi: 10.1016/j.cclet.2023.108656
80. [80]
  C.D. Phung, T.H. Tran, J.O. Kim, Arch. Pharm. Res. 43 (2020) 32–45. doi: 10.1007/s12272-020-01218-1
81. [81]
  E. Einafshar, A.H. Asl, A.H. Nia, et al., Carbohydr. Polym. 194 (2018) 103–110. doi: 10.1016/j.carbpol.2018.03.102
82. [82]
  W.J. Yang, H.Z. Liang, S.H. Ma, D. Wang, J. Huang, Sustain. Mater. Technol. 22 (2019) e00109.
83. [83]
  K. Bromma, D.B. Chithrani, Nanomaterials 10 (2020) 1671. doi: 10.3390/nano10091671
84. [84]
  J.D. Gibson, B.P. Khanal, E.R. Zubarev, J. Am. Chem. Soc. 129 (2007) 11653–11661. doi: 10.1021/ja075181k
85. [85]
  B. Duncan, C. Kim, V.M. Rotello, J. Control. Release 148 (2010) 122–127. doi: 10.1016/j.jconrel.2010.06.004
86. [86]
  E. Boisselier, D. Astruc, Chem. Soc. Rev. 38 (2009) 1759–1782. doi: 10.1039/b806051g
87. [87]
  A. Francois, A. Laroche, N. Pinaud, et al., ChemMedChem 6 (2011) 2003–2008. doi: 10.1002/cmdc.201100311
88. [88]
  Q.N. Nguyen-Trinh, K.X.T. Trinh, N.T. Trinh, et al., Acta Biomater. 143 (2022) 459–470. doi: 10.1016/j.actbio.2022.02.036
89. [89]
  P. Botella, I. Abasolo, Y. Fernandez, et al., J. Control. Release 156 (2011) 246–257. doi: 10.1016/j.jconrel.2011.06.039
90. [90]
  P. Krishnan, M. Rajan, S. Kumari, et al., Sci. Rep. 7 (2017) 10962. doi: 10.1038/s41598-017-09140-1
91. [91]
  S.H. Lee, R. Bajracharya, J.Y. Min, et al., Pharmaceutics 12 (2020) 68. doi: 10.3390/pharmaceutics12010068
92. [92]
  B.A. Cisterna, N. Kamaly, W.I. Choi, et al., Nanomedicine 11 (2016) 2443–2456.
93. [93]
  M. Naeem, U.A. Awan, F. Subhan, et al., Arch. Pharm. Res. 43 (2020) 153–169. doi: 10.1007/s12272-020-01219-0
94. [94]
  X.Q. Zhang, H.L. Song, B.S.B. Canup, B. Xiao, Expert Opin. Drug Deliv. 17 (2020) 781–790. doi: 10.1080/17425247.2020.1748005
95. [95]
  Y.P. Chen, X. Zheng, C.P. Wu, Front. Immunol. 12 (2021) 792691. doi: 10.3389/fimmu.2021.792691
96. [96]
  Y.F. Zou, F. Xiao, L. Song, et al., Int. J. Pharm. 606 (2021) 120888. doi: 10.1016/j.ijpharm.2021.120888
97. [97]
  B. Mansoori, A. Mohammadi, F. Abedi-Gaballu, et al., J. Cell. Physiol. 235 (2020) 6817–6830. doi: 10.1002/jcp.29576
98. [98]
  F. Emami, A. Banstola, A. Vatanara, et al., Mol. Pharm. 16 (2019) 1184–1199. doi: 10.1021/acs.molpharmaceut.8b01157
99. [99]
  Z.Y. Wang, A.M. Zang, Y.N. Wei, et al., Drug Des. Devel. Ther. 14 (2020) 1095–1105. doi: 10.2147/DDDT.S230306
100. [100]
  Y.H. Wei, X.L. Gu, Y.P. Sun, et al., J. Control. Release 319 (2020) 407–415. doi: 10.1016/j.jconrel.2020.01.012
101. [101]
  A.L.C.S.L. Oliveira, L. Zerillo, L.J. Cruz, et al., Mater. Sci. Eng. C 120 (2021) 111678. doi: 10.1016/j.msec.2020.111678
102. [102]
  C.W. Zhao, W.L. Cao, H.L. Zheng, et al., Int. J. Nanomedicine 14 (2019) 1597–1618. doi: 10.2147/IJN.S189923
103. [103]
  Q.L. Song, J.J. Jia, X.X. Niu, et al., Nanoscale 11 (2019) 15958–15970. doi: 10.1039/C9NR03802G
104. [104]
  D.J. Wu, L.X. Zhu, Y. Li, et al., Int. J. Pharm. 584 (2020) 119394. doi: 10.1016/j.ijpharm.2020.119394
105. [105]
  X.L. Gu, M. Qiu, H.L. Sun, et al., Biomater. Sci. 6 (2018) 1526–1534. doi: 10.1039/C8BM00243F
106. [106]
  Y. Shi, S.F. Shan, C.H. Li, et al., Pharm. Res. 37 (2020) 72. doi: 10.1007/s11095-020-02791-2
107. [107]
  R. Narayan, S. Gadag, S.P. Cheruku, et al., Carbohydr. Polym. 261 (2021) 117893. doi: 10.1016/j.carbpol.2021.117893
108. [108]
  S. Iranpour, A.R. Bahrami, S. Nekooei, A. Sh Saljooghi, M.M. Matin, J. Nanobiotechnol. 19 (2021) 314.
109. [109]
  R. Biabanikhankahdani, N.B.M. Alitheen, K.L. Ho, W.S. Tan, Sci. Rep. 6 (2016) 37891. doi: 10.1038/srep37891
110. [110]
  C.Y. Kuo, T.Y. Liu, T.Y. Chan, et al., Colloids Surf. B 140 (2016) 567–573. doi: 10.1016/j.colsurfb.2015.11.008
111. [111]
  I. Pereira, F. Sousa, P. Kennedy, B. Sarmento, Int. J. Pharm. 549 (2018) 397–403. doi: 10.1016/j.ijpharm.2018.08.016
112. [112]
  J. Hu, X.W. Yuan, F. Wang, et al., Chin. Chem. Lett. 32 (2021) 1341–1347. doi: 10.1016/j.cclet.2020.11.006
113. [113]
  S. Zalba, A.M. Contreras, A. Haeri, et al., J. Control. Release 210 (2015) 26–38. doi: 10.1016/j.jconrel.2015.05.271
114. [114]
  Y.M. Tian, S.Y. Tian, D. Wang, et al., Mol. Med. Rep. 20 (2019) 4706–4712.
115. [115]
  K. Kawashima, K. Maeda, C. Saigo, et al., Int. J. Mol. Sci. 18 (2017) 866. doi: 10.3390/ijms18040866
116. [116]
  S.M. Al-Shibli, N. Harun, A.E. Ashour, M.H.B. Mohd Kasmuri, S. Mizan, PeerJ 7 (2019) e7624. doi: 10.7717/peerj.7624
117. [117]
  N. Shahraki, A. Mehrabian, S. Amiri-Darban, S.A. Moosavian, M.R. Jaafari, Colloids Surf. B 200 (2021) 111589. doi: 10.1016/j.colsurfb.2021.111589
118. [118]
  C.H. Wu, Y.H. Kuo, R.L. Hong, H.C. Wu, Sci. Transl. Med. 7 (2015) 290ra291.
119. [119]
  X.L. Gu, Y.H. Wei, Q.Y. Fan, et al., J. Control. Release 301 (2019) 110–118. doi: 10.1016/j.jconrel.2019.03.005
120. [120]
  N. Amino, Y. Ideyama, M. Yamano, et al., Biol. Pharm. Bull. 28 (2005) 2096–2101. doi: 10.1248/bpb.28.2096
121. [121]
  T. Browder, C.E. Butterfield, B.M. Kra¨ling, et al., Cancer Res. 60 (2000) 1878–1886.
122. [122]
  J.B. Xu, G.L. Zhang, X. Luo, et al., Theranostics 11 (2021) 2475–2489. doi: 10.7150/thno.52076
123. [123]
  F. Bai, C. Wang, Q. Lu, et al., Biomaterials 34 (2013) 6163–6174. doi: 10.1016/j.biomaterials.2013.04.062
124. [124]
  L.J. Chen, X.D. She, T. Wang, et al., Nanoscale 7 (2015) 14080–14092. doi: 10.1039/C5NR03527A
125. [125]
  P.P. Wu, Q. Zhou, H.Y. Zhu, Y. Zhuang, J. Bao, BMC Cancer 20 (2020) 354. doi: 10.1186/s12885-020-06803-7
126. [126]
  A. Hashemzadeh, F. Amerizadeh, F. Asgharzadeh, et al., Toxicol. Appl. Pharmacol. 423 (2021) 115573. doi: 10.1016/j.taap.2021.115573
127. [127]
  M.D. Bider, M. Spiess, FEBS Lett. 434 (1998) 37–41. doi: 10.1016/S0014-5793(98)00947-8
128. [128]
  A. Sharma, E.J. Kim, H. Shi, et al., Biomaterials 155 (2018) 145–151. doi: 10.1016/j.biomaterials.2017.11.019
129. [129]
  G. Go, C.S. Lee, Y.M. Yoon, et al., Int. J. Mol. Sci. 22 (2021) 1976. doi: 10.3390/ijms22041976
130. [130]
  W.Q. Yu, M. Shevtsov, X.C. Chen, H.L. Gao, Chin. Chem. Lett. 31 (2020) 1366–1374. doi: 10.1016/j.cclet.2020.02.036
131. [131]
  M. Chen, Y. Xie, Q. Luo, et al., Chin. Chem. Lett. 34 (2023) 107744. doi: 10.1016/j.cclet.2022.107744
132. [132]
  R. Singh, M.K. Mishra, H. Aggarwal, Mediators Inflamm. 2017 (2017) 6027305.
133. [133]
  A. Mantovani, P. Allavena, A. Sica, F. Balkwill, Nature 454 (2008) 436–444. doi: 10.1038/nature07205
134. [134]
  M.M. Hou, Y.X. Zhong, L. Zhang, et al., Chin. Chem. Lett. 32 (2021) 1055–1060. doi: 10.1016/j.cclet.2020.08.0097
135. [135]
  D. Jia, X.B. Ma, Y. Lu, et al., Chin. Chem. Lett. 32 (2021) 162–167. doi: 10.1016/j.cclet.2020.11.052
136. [136]
  Y.A. Li, T. Mei, S.P. Han, et al., Chin. Chem. Lett. 31 (2020) 3027–3040. doi: 10.1016/j.cclet.2020.05.027
137. [137]
  E. Boedtkjer, S.F. Pedersen, Annu. Rev. Physiol. 82 (2020) 103–126. doi: 10.1146/annurev-physiol-021119-034627
138. [138]
  N.M. Anderson, M.C. Simon, Curr. Biol. 30 (2020) R921–R925. doi: 10.1016/j.cub.2020.06.081
139. [139]
  J.Y. Sun, J.Y. Li, X. Li, et al., Chin. Chem. Lett. 34 (2023) 107891. doi: 10.1016/j.cclet.2022.107891
140. [140]
  D. Neri, C.T. Supuran, Nat. Rev. Drug Discov. 10 (2011) 767–777. doi: 10.1038/nrd3554
141. [141]
  S. Hossain, H. Yamamoto, E.H. Chowdhury, et al., PLoS One 8 (2013) e60428. doi: 10.1371/journal.pone.0060428
142. [142]
  X.W. Liu, Y. Hao, R. Popovtzer, L.Z. Feng, Z. Liu, Adv. Healthc. Mater. 10 (2021) e2001167. doi: 10.1002/adhm.202001167
143. [143]
  K. Kessenbrock, V. Plaks, Z. Werb, Cell 141 (2010) 52–67. doi: 10.1016/j.cell.2010.03.015
144. [144]
  P. Vihinen, R. Ala-aho, V.M. Kähäri, Curr. Cancer Drug Targets 5 (2005) 203–220. doi: 10.2174/1568009053765799
145. [145]
  L.L. Shi, Y. Hu, A. Lin, et al., Bioconjug. Chem. 27 (2016) 2943–2953. doi: 10.1021/acs.bioconjchem.6b00643
146. [146]
  Y.C. Wang, H.Y. Xie, K.K. Ying, et al., Biomaterials 270 (2021) 120705. doi: 10.1016/j.biomaterials.2021.120705
147. [147]
  W. Freinbichler, M.A. Colivicchi, C. Stefanini, et al., Cell. Mol. Life Sci. 68 (2011) 2067–2079. doi: 10.1007/s00018-011-0682-x
148. [148]
  K.S. Kim, D. Lee, C.G. Song, P.M. Kang, Nanomedicine 10 (2015) 2709–2723. doi: 10.2217/nnm.15.108
149. [149]
  S. Joshi-Barr, C. de Gracia Lux, E. Mahmoud, A. Almutairi, Antioxid. Redox Signal. 21 (2014) 730–754. doi: 10.1089/ars.2013.57548
150. [150]
  G. Saravanakumar, J. Kim, W.J. Kim, Adv. Sci. 4 (2016) 1600124.
151. [151]
  Q.X. Zhang, F.Z. Zhang, S.S. Li, et al., Theranostics 9 (2019) 3732–3753. doi: 10.7150/thno.34377
152. [152]
  E. Wajs, T.T. Nielsen, K.L. Larsen, A. Fragoso, Nano Res. 9 (2016) 2070–2078. doi: 10.1007/s12274-016-1097-7.10.017
153. [153]
  G.R. Qiu, X. Liu, B.R. Wang, H.B. Gu, W.X. Wang, Polym. Chem. 10 (2019) 2527–2539. doi: 10.1039/C9PY00332K
154. [154]
  H.B. Gu, S.D. Mu, G.R. Qiu, et al., Coord. Chem. Rev. 364 (2018) 51–85. doi: 10.1016/j.ccr.2018.03.013
155. [155]
  Y. Na, J. Woo, W.I. Choi, D. Sung, Colloids Surf. B 200 (2021) 111566. doi: 10.1016/j.colsurfb.2021.111566
156. [156]
  H.Q. Li, W.L. Ye, M.L. Huan, et al., Nanomedicine 14 (2019) 1011–1032. doi: 10.2217/nnm-2018-0227
157. [157]
  Q. Huang, X. Liu, H.Y. Wang, et al., Acta Biomater. 137 (2022) 262–275. doi: 10.1016/j.actbio.2021.10.034
158. [158]
  E.A. Kwizera, E. Chaffin, Y.M. Wang, X.H. Huang, RSC Adv. 7 (2017) 17137–17153. doi: 10.1039/C7RA01224A71|2002|||
159. [159]
  V.V. Mody, A. Cox, S. Shah, et al., Appl. Nanosci. 4 (2014) 385–392. doi: 10.1007/s13204-013-0216-y
160. [160]
  J.M. Poller, J. Zaloga, E. Schreiber, et al., Int. J. Nanomed. 12 (2017) 3207–3220. doi: 10.2147/IJN.S132369
161. [161]
  X.M. Guo, W. Li, L.H. Luo, et al., ACS Appl. Mater. Interfaces 9 (2017) 16581–16593. doi: 10.1021/acsami.6b16513
162. [162]
  H.M. Yoon, M.S. Kang, G.E. Choi, et al., Int. J. Mol. Sci. 22 (2021) 13169. doi: 10.3390/ijms222313169
163. [163]
  X.Y. Zhang, M.Y. Zhao, N. Cao, et al., Biomater. Sci. 8 (2020) 1885–1896. doi: 10.1039/C9BM01927H
164. [164]
  S.P. Yin, J. Huai, X. Chen, et al., Acta Biomater. 26 (2015) 274–285. doi: 10.1016/j.actbio.2015.08.029
165. [165]
  D.L. Chen, S.T. Ge, L.G. Zuo, et al., Drug Deliv. 27 (2020) 1094–1105. doi: 10.1080/10717544.2020.1797245yz%$10.1016/j.cnsns.2013.09.010
166. [166]
  G. Lajoinie, Y. Luan, E. Gelderblom, et al., Commun. Phys. 1 (2018) 22. doi: 10.1038/s42005-018-0020-9
167. [167]
  Y. Luan, G. Lajoinie, E. Gelderblom, et al., Ultrasound Med. Biol. 40 (2014) 1834–1846. doi: 10.1016/j.ultrasmedbio.2014.02.031
168. [168]
  N. Ingram, L.E. McVeigh, R.H. Abou-Saleh, et al., Theranostics 10 (2020) 10973–10992. doi: 10.7150/thno.49670
169. [169]
  X.Y. Yang, X.Y. Zhang, Y.F. Ma, et al., J. Mater. Chem. 19 (2009) 2710–2714. doi: 10.1039/b821416f
170. [170]
  N.G. Shang, P. Papakonstantinou, M. McMullan, et al., Adv. Funct. Mater. 18 (2008) 3506–3514. doi: 10.1002/adfm.200800951
171. [171]
  Y.J. Lu, P.Y. Lin, P.H. Huang, et al., Nanomaterials 8 (2018) 193. doi: 10.3390/nano8040193
172. [172]
  M. Norouzi, B. Nazari, D.W. Miller, Drug Discov. Today 21 (2016) 1835–1849. doi: 10.1016/j.drudis.2016.07.006
173. [173]
  J. Wu, Y. Qu, K. Shi, et al., Chin. Chem. Lett. 29 (2018) 1819–1823. doi: 10.1016/j.cclet.2018.10.004
174. [174]
  A. Mahmood, D. Patel, B. Hickson, J. DesRochers, X. Hu, Int. J. Mol. Sci. 23 (2022) 1415. doi: 10.3390/ijms23031415
175. [175]
  Y. Liu, M. Zhu, M.S. Meng, et al., Chin. Chem. Lett. 34 (2023) 107583. doi: 10.1016/j.cclet.2022.06.006
176. [176]
  H. Cao, L.X. Duan, Y. Zhang, J. Cao, K. Zhang, Signal. Transduct. Target. Ther. 6 (2021) 426. doi: 10.1038/s41392-021-00830-x
177. [177]
  J. Li, Z.S. Wang, H. Han, et al., Chin. Chem. Lett. 33 (2022) 1936–1940. doi: 10.1016/j.cclet.2021.10.058
178. [178]
  X.L. Wu, C.L. He, Y.D. Wu, X.S. Chen, Biomaterials 75 (2016) 148–162. doi: 10.1016/j.biomaterials.2015.10.016
179. [179]
  C. Fiorica, C.A. Ventura, G. Pitarresi, G. Giammona, React. Funct. Polym. 138 (2019) 9–17. doi: 10.1016/j.reactfunctpolym.2019.02.014
180. [180]
  C. Fiorica, F.S. Palumbo, G. Pitarresi, et al., Int. J. Pharm. 589 (2020) 119879. doi: 10.1016/j.ijpharm.2020.119879
181. [181]
  F.Y. Liu, F.Y. Li, G.H. Deng, et al., Macromolecules 45 (2012) 1636–1645. doi: 10.1021/ma202461e
182. [182]
  D.G. Jayne, S. Fook, C. Loi, F. Seow-Choen, Br. J. Surg. 89 (2002) 1545–1550. doi: 10.1046/j.1365-2168.2002.02274.x
183. [183]
  V.J. Verwaal, S. Bruin, H. Boot, G. van Slooten, H. van Tinteren, Ann. Surg. Oncol. 15 (2008) 2426–2432. doi: 10.1245/s10434-008-9966-2
184. [184]
  C.H. Chen, C.Y. Kuo, S.H. Chen, et al., Int. J. Mol. Sci. 19 (2018) 1373. doi: 10.3390/ijms19051373
185. [185]
  Y.S. Wang, C.Y. Gong, L. Yang, et al., BMC Cancer 10 (2010) 402. doi: 10.1186/1471-2407-10-402
186. [186]
  C. Al Sabbagh, J. Seguin, E. Agapova, et al., Eur. J. Pharm. Biopharm. 157 (2020) 154–164. doi: 10.1016/j.ejpb.2020.10.011
187. [187]
  J.E. Lee, S.M. Abuzar, Y. Seo, et al., Int. J. Pharm. 565 (2019) 50–58. doi: 10.1016/j.ijpharm.2019.04.065
188. [188]
  F.Q. Luo, W. Xu, J.Y. Zhang, et al., Acta Biomater 147 (2022) 235–244. doi: 10.1016/j.actbio.2022.05.042
189. [189]
  H. Huang, X.R. Wang, W.L. Wang, et al., Biomaterials 280 (2022) 121289. doi: 10.1016/j.biomaterials.2021.121289
190. [190]
  C.Y. Gong, C. Wang, Y.J. Wang, et al., Nanoscale 4 (2012) 3095–3104. doi: 10.1039/c2nr30278k
191. [191]
  Q. Yun, S.S. Wang, S. Xu, et al., Macromol. Biosci. 17 (2017) 1600262. doi: 10.1002/mabi.201600262
192. [192]
  K.J. De France, K.J. Chan, E.D. Cranston, T. Hoare, Biomacromolecules 17 (2016) 649–660. doi: 10.1021/acs.biomac.5b01598
193. [193]
  Y.T. Ren, X.L. Li, B. Han, et al., Eur. J. Pharm. Sci. 128 (2019) 279–289. doi: 10.1016/j.ejps.2018.12.007
194. [194]
  R.R. Fan, A.P. Tong, X.L. Li, et al., Int. J. Nanomed. 10 (2015) 7291–7305.
195. [195]
  M.C. Arno, M. Inam, A.C. Weems, et al., Nat. Commun. 11 (2020) 1420. doi: 10.1038/s41467-020-15206-y
196. [196]
  A. Mellati, E. Hasanzadeh, M. Gholipourmalekabadi, S.E. Enderami, Mater. Sci. Eng. C 131 (2021) 112489. doi: 10.1016/j.msec.2021.112489
197. [197]
  P. Lavrador, M.R. Esteves, V.M. Gaspar, J.F. Mano, Adv. Funct. Mater. 31 (2020) 2005941.
198. [198]
  F.H. Wang, H. Su, D.Q. Xu, et al., Nat. Biomed. Eng. 4 (2020) 1090–1101. doi: 10.1038/s41551-020-0597-7
199. [199]
  K.J. De France, T. Hoare, E.D. Cranston, Chem. Mater. 29 (2017) 4609–4631. doi: 10.1021/acs.chemmater.7b00531
200. [200]
  M.R. Vakili, W. Mohammed-Saeid, A. Aljasser, et al., Carbohydr. Polym. 255 N(2021) 117332. doi: 10.1016/j.carbpol.2020.117332
201. [201]
  J. Beik, Z. Abed, A. Ghadimi-Daresajini, et al., J. Therm. Biol. 62 (2016) 84–89. doi: 10.1016/j.jtherbio.2016.10.007
202. [202]
  M. Mirrahimi, V. Hosseini, S.K. Kamrava, et al., Artif. Cells Nanomed. Biotechnol. 46 (2018) 241–253.
203. [203]
  S. Her, D.A. Jaffray, C. Allen, Adv. Drug Deliv. Rev. 109 (2017) 84–101. doi: 10.1016/j.addr.2015.12.012
204. [204]
  M. Mirrahimi, M. Khateri, J. Beik, et al., J. Biomed. Mater. Res. B 107 (2019) 2658–2663. doi: 10.1002/jbm.b.34356
205. [205]
  C.Y. Wong, H. Al-Salami, C.R. Dass, Int. J. Pharm. 537 (2018) 223–244. doi: 10.1016/j.ijpharm.2017.12.036
206. [206]
  M. Dai, X. Xu, J. Song, et al., Cancer Lett. 312 (2011) 189–196. doi: 10.1016/j.canlet.2011.08.007
207. [207]
  R.R. Fan, Y.L. Wang, B. Han, et al., Int. J. Biol. Macromol. 69 (2014) 100–107. doi: 10.1016/j.ijbiomac.2014.05.026
208. [208]
  Y. Zhang, Z.R. He, F. Yang, et al., Pharmaceutics 13 (2021) 984. doi: 10.3390/pharmaceutics13070984
209. [209]
  Z.Q. Shi, Q.Q. Li, L. Mei, Chin. Chem. Lett. 31 (2020) 1345–1356. doi: 10.1016/j.cclet.2020.03.001
1. [1]
  Fan Zheng , Runsha Xiao , Shuai Huang , Zhikang Chen , Chen Lai , Anyao Bi , Heying Yao , Xueping Feng , Zihua Chen , Wenbin Zeng . Accurate visualization colorectal cancer by monitoring viscosity variations with a novel mitochondria-targeted fluorescent probe. Chinese Chemical Letters, 2025, 36(2): 109876-. doi: 10.1016/j.cclet.2024.109876
2. [2]
  Yihan Zhou , Duo Gao , Yaying Wang , Li Liang , Qingyu Zhang , Wenwen Han , Jie Wang , Chunliu Zhu , Xinxin Zhang , Yong Gan . Worm-like micelles facilitate the intestinal mucus diffusion and drug accumulation for enhancing colorectal cancer therapy. Chinese Chemical Letters, 2024, 35(6): 108967-. doi: 10.1016/j.cclet.2023.108967
3. [3]
  Tong Tong , Lezong Chen , Siying Wu , Zhong Cao , Yuanbin Song , Jun Wu . Establishment of a leucine-based poly(ester amide)s library with self-anticancer effect as nano-drug carrier for colorectal cancer treatment. Chinese Chemical Letters, 2024, 35(12): 109689-. doi: 10.1016/j.cclet.2024.109689
4. [4]
  Wenjia Wang , Xingyue He , Xiaojie Wang , Tiantian Zhao , Osamu Muraoka , Genzoh Tanabe , Weijia Xie , Tianjiao Zhou , Lei Xing , Qingri Jin , Hulin Jiang . Glutathione-depleted cyclodextrin pseudo-polyrotaxane nanoparticles for anti-inflammatory oxaliplatin (Ⅳ) prodrug delivery and enhanced colorectal cancer therapy. Chinese Chemical Letters, 2024, 35(4): 108656-. doi: 10.1016/j.cclet.2023.108656
5. [5]
  Cheng-Zhe Gao , Hao-Ran Jia , Tian-Yu Wang , Xiao-Yu Zhu , Xiaofeng Han , Fu-Gen Wu . A dual drug-loaded tumor vasculature-targeting liposome for tumor vasculature disruption and hypoxia-enhanced chemotherapy. Chinese Chemical Letters, 2025, 36(1): 109840-. doi: 10.1016/j.cclet.2024.109840
6. [6]
  Ningyue Xu , Jun Wang , Lei Liu , Changyang Gong . Injectable hydrogel-based drug delivery systems for enhancing the efficacy of radiation therapy: A review of recent advances. Chinese Chemical Letters, 2024, 35(8): 109225-. doi: 10.1016/j.cclet.2023.109225
7. [7]
  Zhi Li , Shuya Pan , Yuan Tian , Shaowei Liu , Weifeng Wei , Jinlin Wang , Tianfeng Chen , Ling Wang . Selenium nanoparticles enhance the chemotherapeutic efficacy of pemetrexed against non-small cell lung cancer. Chinese Chemical Letters, 2024, 35(12): 110018-. doi: 10.1016/j.cclet.2024.110018
8. [8]
  Wenbin Zhou , Yafei Gao , Xinyu Feng , Yanqing Zhang , Cong Yang , Lanxi He , Fenghe Zhang , Xiaoguang Li , Qing Li . Biomimetic nanoplatform integrates FRET-enhanced photodynamic therapy and chemotherapy for cascaded revitalization of the tumor immune microenvironment in OSCC. Chinese Chemical Letters, 2025, 36(1): 109763-. doi: 10.1016/j.cclet.2024.109763
9. [9]
  Tingting Hu , Chao Shen , Xueyan Wang , Fengbo Wu , Zhiyao He . Tumor microenvironment-sensitive polymeric nanoparticles for synergetic chemo-photo therapy. Chinese Chemical Letters, 2024, 35(11): 109562-. doi: 10.1016/j.cclet.2024.109562
10. [10]
  Chuyu Huang , Zhishan Liu , Linping Zhao , Zuxiao Chen , Rongrong Zheng , Xiaona Rao , Yuxuan Wei , Xin Chen , Shiying Li . Metal-coordinated oxidative stress amplifier to suppress tumor growth combined with M2 macrophage elimination. Chinese Chemical Letters, 2024, 35(12): 109696-. doi: 10.1016/j.cclet.2024.109696
11. [11]
  Du Liu , Yuyan Li , Hankun Zhang , Benhua Wang , Chaoyi Yao , Minhuan Lan , Zhanhong Yang , Xiangzhi Song . Three-in-one erlotinib-modified NIR photosensitizer for fluorescence imaging and synergistic chemo-photodynamic therapy. Chinese Chemical Letters, 2025, 36(2): 109910-. doi: 10.1016/j.cclet.2024.109910
12. [12]
  Linghui Zou , Meng Cheng , Kaili Hu , Jianfang Feng , Liangxing Tu . Vesicular drug delivery systems for oral absorption enhancement. Chinese Chemical Letters, 2024, 35(7): 109129-. doi: 10.1016/j.cclet.2023.109129
13. [13]
  Yujie Li , Ya-Nan Wang , Yin-Gen Luo , Hongcai Yang , Jinrui Ren , Xiao Li . Advances in synthetic biology-based drug delivery systems for disease treatment. Chinese Chemical Letters, 2024, 35(11): 109576-. doi: 10.1016/j.cclet.2024.109576
14. [14]
  Xiangqian Cao , Chenkai Yang , Xiaodong Zhu , Mengxin Zhao , Yilin Yan , Zhengnan Huang , Jinming Cai , Jingming Zhuang , Shengzhou Li , Wei Li , Bing Shen . Synergistic enhancement of chemotherapy for bladder cancer by photothermal dual-sensitive nanosystem with gold nanoparticles and PNIPAM. Chinese Chemical Letters, 2024, 35(8): 109199-. doi: 10.1016/j.cclet.2023.109199
15. [15]
  Lin Li , Bingjun Sun , Jin Sun , Lin Chen , Zhonggui He . Binary prodrug nanoassemblies combining chemotherapy and ferroptosis activation for efficient triple-negative breast cancer therapy. Chinese Chemical Letters, 2024, 35(10): 109538-. doi: 10.1016/j.cclet.2024.109538
16. [16]
  Huamei Zhang , Jingjing Liu , Mingyue Li , Shida Ma , Xucong Zhou , Aixia Meng , Weina Han , Jin Zhou . Imaging polarity changes in pneumonia and lung cancer using a lipid droplet-targeted near-infrared fluorescent probe. Chinese Chemical Letters, 2024, 35(12): 110020-. doi: 10.1016/j.cclet.2024.110020
17. [17]
  Jiechen Liu , Xiaoguang Li , Ruiyang Xia , Yuqi Wang , Fenghe Zhang , Yongzhi Pang , Qing Li . Efficient suppression of oral squamous cell carcinoma through spatial dimension conversion drug delivery systems-enabled immunomodulatory-photodynamic therapy. Chinese Chemical Letters, 2024, 35(12): 109619-. doi: 10.1016/j.cclet.2024.109619
18. [18]
  Fengjie Liu , Fansu Meng , Zhenjiang Yang , Huan Wang , Yuehong Ren , Yu Cai , Xingwang Zhang . Exosome-biomimetic nanocarriers for oral drug delivery. Chinese Chemical Letters, 2024, 35(9): 109335-. doi: 10.1016/j.cclet.2023.109335
19. [19]
  Jia-Qi Feng , Xiang Tian , Rui-Ge Cao , Yong-Xiu Li , Wen-Long Liu , Rong Huang , Si-Yong Qin , Ai-Qing Zhang , Yin-Jia Cheng . An AIE-based theranostic nanoplatform for enhanced colorectal cancer therapy: Real-time tumor-tracking and chemical-enhanced photodynamic therapy. Chinese Chemical Letters, 2024, 35(12): 109657-. doi: 10.1016/j.cclet.2024.109657
20. [20]
  Zhe Li , Ping-Zhao Liang , Li Xu , Fei-Yu Yang , Tian-Bing Ren , Lin Yuan , Xia Yin , Xiao-Bing Zhang . Three positive charge nonapoptotic-induced photosensitizer with excellent water solubility for tumor therapy. Chinese Chemical Letters, 2024, 35(8): 109190-. doi: 10.1016/j.cclet.2023.109190

Get Citation

PDF

XML

Metrics

PDF Downloads(1)
Abstract views(283)
HTML views(8)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142