Citation: Peiwen Liu, Fang Zhao, Jing Zhang, Yunpeng Bai, Jinxing Ye, Bo Bao, Xinggui Zhou, Li Zhang, Changlu Zhou, Xinhai Yu, Peng Zuo, Jianye Xia, Lian Cen, Yangyang Yang, Guoyue Shi, Lin Xu, Weiping Zhu, Yufang Xu, Xuhong Qian. Micro/nano flow chemistry by Beyond Limits Manufacturing[J]. Chinese Chemical Letters, ;2024, 35(5): 109020. doi: 10.1016/j.cclet.2023.109020 shu

Micro/nano flow chemistry by Beyond Limits Manufacturing

Peiwen Liu ^{a, 1} ,
Fang Zhao ^{b, 1} ,
Jing Zhang ^b ,
Yunpeng Bai ^c ,
Jinxing Ye ^d ,
Bo Bao ^b ,
Xinggui Zhou ^b ,
Li Zhang ^e ,
Changlu Zhou ^b ,
Xinhai Yu ^e ,
Peng Zuo ^c ,
Jianye Xia ^c ,
Lian Cen ^b ,
Yangyang Yang ^a ,
Guoyue Shi ^f ,
Lin Xu ^f ,
Weiping Zhu ^{a, *,} ,
Yufang Xu ^a ,
Xuhong Qian ^{a, f, *,}

a.
State Key Laboratory of Bioreactor Engineering, Shanghai Key Laboratory of Chemical Biology, School of Pharmacy, East China University of Science and Technology, Shanghai 200237, China
b.
State Key Laboratory of Chemical Engineering, School of Chemical Engineering, East China University of Science and Technology, Shanghai 200237, China
c.
State Key Laboratory of Bioreactor Engineering, Shanghai Collaborative Innovation Center for Biomanufacturing, East China University of Science and Technology, Shanghai 200237, China
d.
School of Biomedical and Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou 510006, China
e.
School of Mechanical and Power Engineering, East China University of Science and Technology, Shanghai 200237, China
f.
Shanghai Key Laboratory of Green Chemistry and Chemical Processes, Department of Chemistry, School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200241, China

wpzhu@ecust.edu.cn

xhqian@ecnu.edu.cn

Received Date: 12 August 2023
Revised Date: 28 August 2023
Accepted Date: 29 August 2023
Available Online: 2 September 2023

Figures(11)

In September 2018, we proposed the cutting-edge concept of "Beyond Limits Manufacturing" (BLM). BLM technology is based on the three-dimensional inner engraving or precise outer engraving of ultra-fast laser, to invent micro/nano scale flow chips or devices, which makes it possible for the microform, integration, economy, safety, high efficiency, green and intelligence of research, development and manufacturing process, so as to realize transformational manufacturing in the era of Industry 4.0. In this paper, we reviewed the representative results we made in the field of micro/nano flow chemistry during the implementation of the BLM major project (December 2019 to August 2023), and discussed its application prospects in micro/nano flow chemistry.
- Beyond Limits Manufacturing,
- Flow chemistry,
- Pharmaceutical manufacturing,
- Microreactor
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