Citation: Yongxin Pan, Yuetian Guo, Ying Li, Lijun Tang, Xiaomei Yan. A new aggregation-induced emission-based fluorescent probe for effective detection of Hg²⁺ and its multiple applications[J]. Chinese Chemical Letters, ;2023, 34(12): 108237. doi: 10.1016/j.cclet.2023.108237 shu

A new aggregation-induced emission-based fluorescent probe for effective detection of Hg²⁺ and its multiple applications

Yongxin Pan ^{a, 1} ,
Yuetian Guo ^{a, 1} ,
Ying Li ^a ,
Lijun Tang ^{a, b, *,} ,
Xiaomei Yan ^{c, **,}

a.
College of Chemistry and Materials Engineering, Bohai University, Jinzhou 121013, China
b.
Department of Chemistry, National Demonstration Center for Experimental Chemistry Education, Yanbian University, Yanji 133002, China
c.
College of Laboratory Medicine, Dalian Medical University, Dalian 116044, China

^**

ljtang@bhu.edu.cn

xmyan1978@sina.com

Received Date: 18 November 2022
Revised Date: 13 February 2023
Accepted Date: 15 February 2023
Available Online: 25 February 2023

Figures(4)

Detection of mercury ions (Hg²⁺) in actual samples is of significant importance due to the toxicity of Hg²⁺ to human health. In this work, a simple tetraphenylethene (TPE) derived fluorescent probe TPE-Hg based on aggregation-induced emission (AIE) mechanism was synthesized. TPE-Hg can visually recognize Hg²⁺ in THF/HEPES (1:9, v/v, HEPES 20 mmol/L, pH 7.3) system with rapid response, strong anti-interference ability, large Stokes shift (203 nm), and low detection limit (7.548 × 10⁻⁷ mol/L). The results show that Hg²⁺ triggered elimination of TPE-Hg lead to releasing of an AIE-active compound 2 is responsible to the sensing mechanism. TPE-Hg is applicable to detect Hg²⁺ in actual water samples and image Hg²⁺ in living MCF-7 cells. In addition, TPE-Hg is suitable to assay the Hg²⁺ level in seafood and tea samples, and it is also applicable in test strips.
- Aggregation-induced emission,
- Fluorescent probe,
- Food samples,
- Cell imaging,
- Hg(Ⅱ)
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通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142

A new aggregation-induced emission-based fluorescent probe for effective detection of Hg2+ and its multiple applications

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通讯作者: 陈斌, bchen63@163.com

A new aggregation-induced emission-based fluorescent probe for effective detection of Hg²⁺ and its multiple applications