Citation: Yuerong Wang, Yang Lei, Jiaye Wang, Hui Yang, Leming Sun. Tetrapeptide self-assembled multicolor fluorescent nanoparticles for bioimaging applications[J]. Chinese Chemical Letters, ;2023, 34(6): 107915. doi: 10.1016/j.cclet.2022.107915 shu

Tetrapeptide self-assembled multicolor fluorescent nanoparticles for bioimaging applications

School of Life Sciences, Key Laboratory of Space Bioscience & Biotechnology, Northwestern Polytechnical University, Xi'an 710072, China

kittyyh@nwpu.edu.cn

lmsun@nwpu.edu.cn

Received Date: 13 August 2022
Revised Date: 12 October 2022
Accepted Date: 17 October 2022
Available Online: 19 October 2022

Figures(4)

The biocompatibility and biodegradability of peptide self-assembled materials makes them suitable for many biological applications, such as targeted drug delivery, bioimaging, and tracking of therapeutic agents. According to our previous research, self-assembled fluorescent peptide nanoparticles can overcome the intrinsic optical properties of peptides. However, monochromatic fluorescent nanomaterials have many limitations as luminescent agents in biomedical applications. Therefore, combining different fluorescent species into one nanostructure to prepare fluorescent nanoparticles with multiple emission wavelengths has become a very attractive research area in the bioimaging field. In this study, the tetrapeptide Trp-Trp-Trp-Trp (WWWW) was self-assembled into multicolor fluorescent nanoparticles (TPNPs). The results have demonstrated that TPNPs have the blue, green, red and near infrared (NIR) fluorescence emission wavelength. Moreover, TPNPs have shown excellent performance in multicolor bioimaging, biocompatibility, and photostability. The facile preparation and multicolor fluorescence features make TPNPs potentially useful in multiplex bioanalysis and diagnostics.
- Self-assembly,
- Tetrapeptide,
- Multicolor,
- Fluorescent nanoparticles,
- Bioimaging
1. [1]
  E. Busseron, Y. Ruff, E. Moulin, N. Giuseppone, Nanoscale 5 (2013) 7098–7140. doi: 10.1039/c3nr02176a
2. [2]
  Y. Chen, A.A. Orr, K. Tao, Z.B. Wang, et al., ACS Nano 14 (2020) 2798–2807. doi: 10.1021/acsnano.9b10024
3. [3]
  L.L. Zhao, Y.L. Xing, R. Wang, et al., ACS Appl. Bio. Mater. 3 (2020) 86–106. doi: 10.1021/acsabm.9b00843
4. [4]
  L. Sun, A. Li, Y. Hu, et al., Part. Part. Syst. Charact. 36 (2019) 1800420. doi: 10.1002/ppsc.201800420
5. [5]
  J. Wang, K. Liu, R.R. Xing, X.H. Yan, Chem. Soc. Rev. 45 (2016) 5589–5604. doi: 10.1039/C6CS00176A
6. [6]
  D.C. Liu, D.J. Fu, L.B. Zhang, L.M. Sun, Chin. Chem. Lett. 32 (2021) 1066–1070. doi: 10.1016/j.cclet.2020.09.009
7. [7]
  S. Chen, Y.Z. Liu, R. Liang, et al., Chin. Chem. Lett. 32 (2021) 3903–3906. doi: 10.1016/j.cclet.2021.06.041
8. [8]
  Q.B. Meng, Y.Y. Kou, X. Ma, et al., Langmuir 28 (2012) 5017–5022. doi: 10.1021/la3003355
9. [9]
  Y.X. Li, L.Y. Yan, K. Liu, et al., Small 12 (2016) 2575–2579. doi: 10.1002/smll.201600230
10. [10]
  N. Habibi, N. Kamaly, A. Memic, H. Shafiee, Nano Today 11 (2016) 41–60. doi: 10.1016/j.nantod.2016.02.004
11. [11]
  Y. Wang, Y.X. Lin, Z.Y. Qiao, et al., Adv. Mater. 27 (2015) 2627–2634. doi: 10.1002/adma.201405926
12. [12]
  R.F. Silva, D.R. Araujo, E.R. Silva, et al., Langmuir 29 (2013) 10205–10212. doi: 10.1021/la4019162
13. [13]
  Z. Fan, L.M. Sun, Y.J. Huang, et al., Nat. Nanotechnol. 11 (2016) 388–394. doi: 10.1038/nnano.2015.312
14. [14]
  W. Lin, Y. Yang, Y. Lei, et al., ACS Appl. Mater. Interfaces 13 (2021) 32799–32809. doi: 10.1021/acsami.1c07983
15. [15]
  D.J. Fu, D.C. Liu, L.B. Zhang, L.M. Sun, Chin. Chem. Lett. 31 (2020) 3195–3199. doi: 10.1016/j.cclet.2020.07.011
16. [16]
  L.M. Sun, Y. Lei, Y.R. Wang, D.C. Liu, Chin. Chem. Lett. 33 (2022) 1946–1950. doi: 10.1016/j.cclet.2021.10.071
17. [17]
  L.M. Sun, D.C. Liu, D.J. Fu, et al., Chem. Eng. J. 405 (2021) 126733. doi: 10.1016/j.cej.2020.126733
18. [18]
  L.M. Sun, Z. Fan, T. Yue, et al., Bio-Des. Manuf. 1 (2018) 182–194. doi: 10.1007/s42242-018-0019-9
19. [19]
  Z. Fan, Y. Chang, C.C. Cui, et al., Nat. Commun. 9 (2018) 3217. doi: 10.1038/s41467-018-05568-9
20. [20]
  J. Kong, J.X. Zhang, Y.F. Wang, et al., ACS Appl. Mater. Interfaces 12 (2020) 31830–31841. doi: 10.1021/acsami.0c08259
21. [21]
  J. Liu, J. Liu, W.S. Liu, et al., Inorg. Chem. 54 (2015) 7725–7734. doi: 10.1021/acs.inorgchem.5b00610
22. [22]
  X.C. Liu, J.B. Fei, A.H. Wang, et al., Angew. Chem. Int. Ed. 56 (2017) 2660–2663. doi: 10.1002/anie.201612024
23. [23]
  K. Tao, P. Makam, R. Aizen, E. Gazit, Science 358 (2017) eaam9756. doi: 10.1126/science.aam9756
24. [24]
  Y.Q. Yan, H. Wang, Y.L. Zhao, Chin. Chem. Lett. 33 (2022) 3361–3370. doi: 10.1016/j.cclet.2022.02.016
25. [25]
  J. Chen, P.S. Zhang, G. Fang, et al., J. Phys. Chem. B 116 (2012) 4354–4362. doi: 10.1021/jp2110659
26. [26]
  G. Gao, Y.W. Jiang, W. Sun, F.G. Wu, Chin. Chem. Lett. 29 (2018) 1475–1485. doi: 10.1016/j.cclet.2018.07.004
27. [27]
  S. He, Q.T. Huang, Y. Zhang, et al., Chin. Chem. Lett. 32 (2021) 1462–1465. doi: 10.1016/j.cclet.2020.09.047
28. [28]
  X. Geng, Y.Q. Sun, Z.H. Li, et al., Small 15 (2019) 1901517. doi: 10.1002/smll.201901517
29. [29]
  Y.C. Wang, R. Hu, G.M. Lin, et al., ACS Appl. Mater. Interfaces 5 (2013) 2786–2799. doi: 10.1021/am302030a
30. [30]
  Y. Rong, C.F. Wu, J.B. Yu, et al., ACS Nano 7 (2013) 376–384. doi: 10.1021/nn304376z
31. [31]
  D.D. Yao, S.S. Zhao, J.H. Guo, et al., J. Mater. Chem. 21 (2011) 3568–3570. doi: 10.1039/c1jm00009h
32. [32]
  K. Jiang, S. Sun, L. Zhang, et al., Angew. Chem. Int. Ed. 54 (2015) 5360–5363. doi: 10.1002/anie.201501193
33. [33]
  K.N. Wang, W. Ma, Y.C. Xu, et al., Chin. Chem. Lett. 31 (2020) 3149–3152. doi: 10.1016/j.cclet.2020.08.039
34. [34]
  F. Yang, D. Zhang, Q.M. Zhou, et al., Chin. Chem. Lett. 33 (2022) 2901–2905. doi: 10.1016/j.cclet.2021.10.028
35. [35]
  X.K. Chen, X.D. Zhang, F.G. Wu, Chin. Chem. Lett. 32 (2021) 3048–3052. doi: 10.1016/j.cclet.2021.03.061
36. [36]
  J.J. Panda, V.S. Chauhan, Polym. Chem. 5 (2014) 4418–4436.
37. [37]
  C.H. Chen, X.H. Ji, Chin. Chem. Lett. 29 (2018) 1287–1290. doi: 10.1016/j.cclet.2017.10.013
38. [38]
  K. Tao, Y. Chen, A.A. Orr, et al., Adv. Funct. Mater. 30 (2020) 1909614. doi: 10.1002/adfm.201909614
39. [39]
  X.X. Shi, P. Yang, X.F. Peng, et al., Polymer 170 (2019) 65–75. doi: 10.1016/j.polymer.2019.03.008
40. [40]
  J. Kang, D. Miyajima, T. Mori, et al., Science 347 (2015) 646–651. doi: 10.1126/science.aaa4249
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2. [2]
  Zengchao Guo , Weiwei Liu , Tengfei Liu , Jinpeng Wang , Hui Jiang , Xiaohui Liu , Yossi Weizmann , Xuemei Wang . Engineered exosome hybrid copper nanoscale antibiotics facilitate simultaneous self-assembly imaging and elimination of intracellular multidrug-resistant superbugs. Chinese Chemical Letters, 2024, 35(7): 109060-. doi: 10.1016/j.cclet.2023.109060
3. [3]
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4. [4]
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5. [5]
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6. [6]
  Jingqi Xin , Shupeng Han , Meichen Zheng , Chenfeng Xu , Zhongxi Huang , Bin Wang , Changmin Yu , Feifei An , Yu Ren . A nitroreductase-responsive nanoprobe with homogeneous composition and high loading for preoperative non-invasive tumor imaging and intraoperative guidance. Chinese Chemical Letters, 2024, 35(7): 109165-. doi: 10.1016/j.cclet.2023.109165
7. [7]
  Keyang Li , Yanan Wang , Yatao Xu , Guohua Shi , Sixian Wei , Xue Zhang , Baomei Zhang , Qiang Jia , Huanhua Xu , Liangmin Yu , Jun Wu , Zhiyu He . Flash nanocomplexation (FNC): A new microvolume mixing method for nanomedicine formulation. Chinese Chemical Letters, 2024, 35(10): 109511-. doi: 10.1016/j.cclet.2024.109511
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9. [9]
  Xiaofei NIU , Ke WANG , Fengyan SONG , Shuyan YU . Self-assembly of [Pd₆(L)₄]⁸⁺-type macrocyclic complexes for fluorescent sensing of HSO₃^-. Chinese Journal of Inorganic Chemistry, 2024, 40(7): 1233-1242. doi: 10.11862/CJIC.20240057
10. [10]
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11. [11]
  Zhenzhu Wang , Chenglong Liu , Yunpeng Ge , Wencan Li , Chenyang Zhang , Bing Yang , Shizhong Mao , Zeyuan Dong . Differentiated self-assembly through orthogonal noncovalent interactions towards the synthesis of two-dimensional woven supramolecular polymers. Chinese Chemical Letters, 2024, 35(5): 109127-. doi: 10.1016/j.cclet.2023.109127
12. [12]
  Haiyang Gu , Xiang Xu . Multicolor hybrid metal halides and anti-counterfeiting. Chinese Journal of Structural Chemistry, 2024, 43(9): 100352-100352. doi: 10.1016/j.cjsc.2024.100352
13. [13]
  Changhui Yu , Peng Shang , Huihui Hu , Yuening Zhang , Xujin Qin , Linyu Han , Caihe Liu , Xiaohan Liu , Minghua Liu , Yuan Guo , Zhen Zhang . Evolution of template-assisted two-dimensional porphyrin chiral grating structure by directed self-assembly using chiral second harmonic generation microscopy. Chinese Chemical Letters, 2024, 35(10): 109805-. doi: 10.1016/j.cclet.2024.109805
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  Xingwen Cheng , Haoran Ren , Jiangshan Luo . Boosting the self-trapped exciton emission in vacancy-ordered double perovskites via supramolecular assembly. Chinese Journal of Structural Chemistry, 2024, 43(6): 100306-100306. doi: 10.1016/j.cjsc.2024.100306
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  Wenyi Mei , Lijuan Xie , Xiaodong Zhang , Cunjian Shi , Fengzhi Wang , Qiqi Fu , Zhenjiang Zhao , Honglin Li , Yufang Xu , Zhuo Chen . Design, synthesis and biological evaluation of fluorescent derivatives of ursolic acid in living cells. Chinese Chemical Letters, 2024, 35(5): 108825-. doi: 10.1016/j.cclet.2023.108825
16. [16]
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17. [17]
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18. [18]
  Zhiwen Li , Jingjing Zhang , Gao Li . Dynamic assembly of chiral golden knots. Chinese Journal of Structural Chemistry, 2024, 43(7): 100300-100300. doi: 10.1016/j.cjsc.2024.100300
19. [19]
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