Citation: Chaojun Zhang, Yang Tang, Qin Wang, Yunxiang He, Xiaoling Wang, Sebastian Beyer, Junling Guo. Near infrared light-induced dynamic modulation of enzymatic activity through polyphenol-functionalized liquid metal nanodroplets[J]. Chinese Chemical Letters, ;2023, 34(2): 107795. doi: 10.1016/j.cclet.2022.107795 shu

Near infrared light-induced dynamic modulation of enzymatic activity through polyphenol-functionalized liquid metal nanodroplets

Chaojun Zhang ^a ,
Yang Tang ^a ,
Qin Wang ^{a, b} ,
Yunxiang He ^{a, c} ,
Xiaoling Wang ^{a, c, *,} ,
Sebastian Beyer ^d ,
Junling Guo ^{a, c, e, f, *,}

a.
BMI Center for Biomass Materials and Nanointerfaces, College of Biomass Science and Engineering, Sichuan University, Chengdu 610065, China
b.
School of Pharmacy, Southwest Minzu University, Chengdu 610225, China
c.
National Engineering Research Center of Clean Technology in Leather Industry, Sichuan University, Chengdu 610065, China
d.
Department of Biomedical Engineering, Chinese University of Hong Kong, Hong Kong 999077, China
e.
State Key Laboratory of Polymer Materials Engineering, Sichuan University, Chengdu 610065, China
f.
Bioproducts Institute, Department of Chemical and Biological Engineering, University of British Columbia, Vancouver, BC V6T 1Z4, Canada

xlwang@scu.edu.cn

junling.guo@ubc.ca

Received Date: 21 July 2022
Revised Date: 18 August 2022
Accepted Date: 1 September 2022
Available Online: 17 October 2022

Figures(4)

Dynamic manipulation of enzymatic activity is a challenging task for applications in chemical and pharmaceutical industries due to the difficult modification and variable conformation of various enzymes. Here, we report a new strategy for reversible dynamic modulation of enzymatic activity by near-infrared light-induced photothermal conversion based on polyphenol-functionalized liquid metal nanodroplets (LM). The metal-phenolic nanocoating not only provides colloidal stability of LM nanodroplets but also generates nanointerfaces for the assembly of various enzymes on the LM nanodroplets. Upon near infrared (NIR) irradiation, the localized microenvironmental heating through photothermal effect of the LM nanodroplets allows tailoring the enzymatic activity without affecting the bulk temperature. A library of functional enzymes, including proteinase K, glucoamylase, glucose oxidase, and Bst DNA polymerase, is integrated to perform a reversible control and enhanced activities even after five times of cycles, demonstrating great potential in bacterial fermentation, bacteriostasis, and target gene amplification.
- Enzymatic activity,
- Photo-modulation,
- Near infrared light,
- Liquid metal nanodroplets,
- Metal-phenolic nanocoating
1. [1]
  R.A. Sheldon, J.M. Woodley, Chem. Rev. 118 (2018) 801–838. doi: 10.1021/acs.chemrev.7b00203
2. [2]
  S. Zhang, S. Liu, Y. Sun, et al., Chem. Soc. Rev. 50 (2021) 13449–13466. doi: 10.1039/d1cs00392e
3. [3]
  P. Intasian, K. Prakinee, A. Phintha, et al., Chem. Rev. 121 (2021) 10367–10451. doi: 10.1021/acs.chemrev.1c00121
4. [4]
  E.M. Zhao, Y. Zhang, J. Mehl, et al., Nature 555 (2018) 683–687. doi: 10.1038/nature26141
5. [5]
  K.G. Kumaraswamy, A. Krishnan, G. Ananyev, et al., Energ. Environ. Sci. 12 (2019) 1035–1045. doi: 10.1039/c8ee03606c
6. [6]
  M. Wensien, F.R. von Pappenheim, L.M. Funk, et al., Nature 593 (2021) 460–464. doi: 10.1038/s41586-021-03513-3
7. [7]
  X.X. Zhou, L.Z. Fan, P. Li, et al., Science 355 (2017) 836–842. doi: 10.1126/science.aah3605
8. [8]
  A.H.G. David, R. Casares, J.M. Cuerva, et al., J. Am. Chem. Soc. 141 (2019) 18064–18074. doi: 10.1021/jacs.9b07143
9. [9]
  J.A. Frank, D.A. Yushchenko, D.J. Hodson, et al., Nat. Chem. Biol. 12 (2016) 755–762. doi: 10.1038/nchembio.2141
10. [10]
  T. Tian, Y. Song, J. Wang, et al., J. Am. Chem. Soc. 138 (2016) 955–961. doi: 10.1021/jacs.5b11532
11. [11]
  K. Chen, F.H. Arnold, Nat. Catal. 3 (2020) 203–213. doi: 10.1038/s41929-019-0385-5
12. [12]
  Y. Zhou, C. Zhou, Nat. Chem. 13 (2021) 299–301. doi: 10.1038/s41557-021-00669-3
13. [13]
  C. Xu, W. Bing, F. Wang, et al., ACS Nano 11 (2017) 7770–7780. doi: 10.1021/acsnano.7b01450
14. [14]
  A.V. Leopold, K.G. Chernov, A.A. Shemetov, et al., Nat. Commun. 10 (2019) 1129. doi: 10.1038/s41467-019-08988-3
15. [15]
  S. Chen, A.Z. Weitemier, X. Zeng, et al., Science 359 (2018) 679–684. doi: 10.1126/science.aaq1144
16. [16]
  C. Wang, Q. Zhang, X. Wang, et al., Angew. Chem. Int. Ed. 56 (2017) 6767–6772. doi: 10.1002/anie.201700968
17. [17]
  S. Zhang, C. Wang, H. Chang, et al., Sci. Adv. 5 (2019) eaaw4252. doi: 10.1126/sciadv.aaw4252
18. [18]
  H.R. de Barros, I. García, C. Kuttner, et al., ACS Catal. 11 (2020) 414–423.
19. [19]
  S.A. Thompson, S. Paterson, M.M. Azab, et al., Small 13 (2017) 1603195. doi: 10.1002/smll.201603195
20. [20]
  E.J. Markvicka, M.D. Bartlett, X. Huang, et al., Nat. Mater. 17 (2018) 618–624. doi: 10.1038/s41563-018-0084-7
21. [21]
  S.A. Chechetka, Y. Yu, X. Zhen, et al., Nat. Commun. 8 (2017) 15432. doi: 10.1038/ncomms15432
22. [22]
  Y. Liu, W. Zhang, H. Wang, Mater. Horiz. 8 (2021) 56–77. doi: 10.1039/D0MH01117G
23. [23]
  C.J. Thrasher, Z.J. Farrell, N.J. Morris, et al., Adv. Mater. 31 (2019) e1903864. doi: 10.1002/adma.201903864
24. [24]
  X. Li, M. Li, L. Zong, et al., Adv. Funct. Mater. 28 (2018) 1804197. doi: 10.1002/adfm.201804197
25. [25]
  X. Li, M. Li, J. Xu, et al., Nat. Commun. 10 (2019) 3514. doi: 10.1038/s41467-019-11466-5
26. [26]
  Y. Lu, Q. Hu, Y. Lin, et al., Nat. Commun. 6 (2015) 10066. doi: 10.1038/ncomms10066
27. [27]
  J. Yan, M.H. Malakooti, Z. Lu, et al., Nat. Nanotechnol. 14 (2019) 684–690. doi: 10.1038/s41565-019-0454-6
28. [28]
  F. Centurion, M.G. Saborio, F.M. Allioux, et al., Chem. Commun. 55 (2019) 11291–11294. doi: 10.1039/c9cc06081b
29. [29]
  J. Chen, S. Pan, J. Zhou, et al., Adv. Mater. (2021) e2108624.
30. [30]
  M. Shin, H.A. Lee, M. Lee, et al., Nat. Biomed. Eng. 2 (2018) 304–317. doi: 10.1038/s41551-018-0227-9
31. [31]
  D.J.A. Jenkins, C.W.C. Kendall, J.L. Sievenpiper, J. Am. Coll. Cardiol. 78 (2021) 679–682. doi: 10.1016/j.jacc.2021.06.014
32. [32]
  J. Guo, B.L. Tardy, A.J. Christofferson, et al., Nat. Nanotechnol. 11 (2016) 1105–1111. doi: 10.1038/nnano.2016.172
33. [33]
  Y. Han, Z. Lin, J. Zhou, et al., Angew. Chem. Int. Ed. 59 (2020) 15618–15625. doi: 10.1002/anie.202002089
34. [34]
  J. Guo, Y. Ping, H. Ejima, et al., Angew. Chem. Int. Edit. 53 (2014) 5546–5551. doi: 10.1002/anie.201311136
35. [35]
  M.A. Rahim, G. Lin, P.P. Tomanin, et al., ACS Appl. Mater. Inter. 12 (2020) 3746–3754. doi: 10.1021/acsami.9b19097
36. [36]
  Y. Xu, R. Rothe, D. Voigt, et al., Nat. Commun. 12 (2021) 2407. doi: 10.1109/lawp.2021.3113319
37. [37]
  M.A. Rahim, F. Centurion, J. Han, et al., Adv. Funct. Mater. 31 (2020) 2007336.
38. [38]
  H. Tian, B. Li, S.E. Evivie, et al., Int. J. Mol. Sci. 19 (2018).
39. [39]
  N.S. Terefe, M.A. Augustin, Crit. Rev. Food Sci. 60 (2020) 2887–2913. doi: 10.1080/10408398.2019.1666250
40. [40]
  D. Ribeaucourt, G.T. Hofler, M. Yemloul, et al., ACS Catal. 12 (2022) 1111–1116. doi: 10.1021/acscatal.1c05334
41. [41]
  T.H. Kim, S. -. H. Kang, J.E. Han, et al., ACS Catal. 10 (2020) 4871–4878. doi: 10.1021/acscatal.9b05426
42. [42]
  M.M. Kaminski, O.O. Abudayyeh, J.S. Gootenberg, et al., Nat. Biomed. Eng. 5 (2021) 643–656. doi: 10.1038/s41551-021-00760-7
43. [43]
  M. You, Z. Li, S. Feng, et al., Trends Biotechnol. 38 (2020) 637–649. doi: 10.1016/j.tibtech.2019.12.006
44. [44]
  H. Ravan, M. Amandadi, N. Sanadgol, Microb. Pathogenesis 91 (2016) 161–165. doi: 10.1016/j.micpath.2015.12.011
1. [1]
  Rui Wang , He Qi , Haijiao Zheng , Qiong Jia . Light/pH dual-responsive magnetic metal-organic frameworks composites for phosphorylated peptide enrichment. Chinese Chemical Letters, 2024, 35(7): 109215-. doi: 10.1016/j.cclet.2023.109215
2. [2]
  Lang Gao , Cen Zhou , Rui Wang , Feng Lan , Bohang An , Xiaozhou Huang , Xiao Zhang . Unveiling inverse vulcanized polymers as metal-free, visible-light-driven photocatalysts for cross-coupling reactions. Chinese Chemical Letters, 2024, 35(4): 108832-. doi: 10.1016/j.cclet.2023.108832
3. [3]
  Wenxiang Ma , Xinyu He , Tianyi Chen , De-Li Ma , Hongzheng Chen , Chang-Zhi Li . Near-infrared non-fused electron acceptors for efficient organic photovoltaics. Chinese Chemical Letters, 2024, 35(4): 109099-. doi: 10.1016/j.cclet.2023.109099
4. [4]
  Yudi Cheng , Xiao Wang , Jiao Chen , Zihan Zhang , Jiadong Ou , Mengyao She , Fulin Chen , Jianli Li . A near-infrared fluorescent probe for visualizing transformation pathway of Cys/Hcy and H₂S and its applications in living system. Chinese Chemical Letters, 2024, 35(5): 109156-. doi: 10.1016/j.cclet.2023.109156
5. [5]
  Lei Wang , Jun-Jie Wu , Chang-Cun Yan , Wan-Ying Yang , Zong-Lu Che , Xin-Yu Xia , Xue-Dong Wang , Liang-Sheng Liao . Near-infrared organic lasers with ultra-broad emission bands by simultaneously harnessing four-level and six-level systems. Chinese Chemical Letters, 2024, 35(8): 109365-. doi: 10.1016/j.cclet.2023.109365
6. [6]
  Ying Zhao , Yin-Hang Chai , Tian Chen , Jie Zheng , Ting-Ting Li , Francisco Aznarez , Li-Long Dang , Lu-Fang Ma . Size-controlled synthesis and near-infrared photothermal response of Cp* Rh-based metalla[2]catenanes and rectangular metallamacrocycles. Chinese Chemical Letters, 2024, 35(6): 109298-. doi: 10.1016/j.cclet.2023.109298
7. [7]
  Yikun Wang , Qiaomei Chen , Shijie Liang , Dongdong Xia , Chaowei Zhao , Christopher R. McNeill , Weiwei Li . Near-infrared double-cable conjugated polymers based on alkyl linkers with tunable length for single-component organic solar cells. Chinese Chemical Letters, 2024, 35(4): 109164-. doi: 10.1016/j.cclet.2023.109164
8. [8]
  Lixian Fu , Yiyun Tan , Yue Ding , Weixia Qing , Yong Wang . Water–soluble and polarity–sensitive near–infrared fluorescent probe for long–time specific cancer cell membranes imaging and C. Elegans label. Chinese Chemical Letters, 2024, 35(4): 108886-. doi: 10.1016/j.cclet.2023.108886
9. [9]
  Xuan Zhu , Lin Zhou , Xiao-Yun Huang , Yan-Ling Luo , Xin Deng , Xin Yan , Yan-Juan Wang , Yan Qin , Yuan-Yuan Tang . (Benzimidazolium)2GeI4: A layered two-dimensional perovskite with dielectric switching and broadband near-infrared photoluminescence. Chinese Journal of Structural Chemistry, 2024, 43(6): 100272-100272. doi: 10.1016/j.cjsc.2024.100272
10. [10]
  Yiyue Ding , Qiuxiang Zhang , Lei Zhang , Qilu Yao , Gang Feng , Zhang-Hui Lu . Exceptional activity of amino-modified rGO-immobilized PdAu nanoclusters for visible light-promoted dehydrogenation of formic acid. Chinese Chemical Letters, 2024, 35(7): 109593-. doi: 10.1016/j.cclet.2024.109593
11. [11]
  Xuejian Xing , Pan Zhu , E Pang , Shaojing Zhao , Yu Tang , Zheyu Hu , Quchang Ouyang , Minhuan Lan . D-A-D-structured boron-dipyrromethene with aggregation-induced enhanced phototherapeutic efficiency for near-infrared fluorescent and photoacoustic imaging-guided synergistic photodynamic and photothermal cancer therapy. Chinese Chemical Letters, 2024, 35(10): 109452-. doi: 10.1016/j.cclet.2023.109452
12. [12]
  Kebo Xie , Qian Zhang , Fei Ye , Jungui Dai . A multi-enzymatic cascade reaction for the synthesis of bioactive C-oligosaccharides. Chinese Chemical Letters, 2024, 35(6): 109028-. doi: 10.1016/j.cclet.2023.109028
13. [13]
  Liliang Chu , Xiaoyan Zhang , Jianing Li , Xuelei Deng , Miao Wu , Ya Cheng , Weiping Zhu , Xuhong Qian , Yunpeng Bai . Continuous-flow synthesis of polysubstituted γ-butyrolactones via enzymatic cascade catalysis. Chinese Chemical Letters, 2024, 35(4): 108896-. doi: 10.1016/j.cclet.2023.108896
14. [14]
  Junhan Luo , Qi Qing , Liqin Huang , Zhe Wang , Shuang Liu , Jing Chen , Yuexiang Lu . Non-contact gaseous microplasma electrode as anode for electrodeposition of metal and metal alloy in molten salt. Chinese Chemical Letters, 2024, 35(4): 108483-. doi: 10.1016/j.cclet.2023.108483
15. [15]
  Ying Li , Yanjun Xu , Xingqi Han , Di Han , Xuesong Wu , Xinlong Wang , Zhongmin Su . A new metal–organic rotaxane framework for enhanced ion conductivity of solid-state electrolyte in lithium-metal batteries. Chinese Chemical Letters, 2024, 35(9): 109189-. doi: 10.1016/j.cclet.2023.109189
16. [16]
  Guangyao Wang , Zhitong Xu , Ye Qi , Yueguang Fang , Guiling Ning , Junwei Ye . Electrospun nanofibrous membranes with antimicrobial activity for air filtration. Chinese Chemical Letters, 2024, 35(10): 109503-. doi: 10.1016/j.cclet.2024.109503
17. [17]
  Guoliang Liu , Zhiqiang Liu , Anmin Zheng . Modulation of zeolite surface realizes dynamic copper species redispersion. Chinese Journal of Structural Chemistry, 2024, 43(6): 100308-100308. doi: 10.1016/j.cjsc.2024.100308
18. [18]
  Jian Ji , Jie Yan , Honggen Peng . Modulation of dinuclear site by orbital coupling to boost catalytic performance. Chinese Journal of Structural Chemistry, 2024, 43(8): 100360-100360. doi: 10.1016/j.cjsc.2024.100360
19. [19]
  Lihua Ma , Song Guo , Zhi-Ming Zhang , Jin-Zhong Wang , Tong-Bu Lu , Xian-Shun Zeng . Sensitizing photoactive metal–organic frameworks via chromophore for significantly boosting photosynthesis. Chinese Chemical Letters, 2024, 35(5): 108661-. doi: 10.1016/j.cclet.2023.108661
20. [20]
  Ziyi Zhu , Yang Cao , Jun Zhang . CO2-switched porous metal-organic framework magnets. Chinese Journal of Structural Chemistry, 2024, 43(2): 100241-100241. doi: 10.1016/j.cjsc.2024.100241

Get Citation

PDF

XML

Metrics

PDF Downloads(0)
Abstract views(316)
HTML views(25)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142