Citation: Wei-Bao He, Sai-Jie Zhao, Jing-Yang Chen, Jun Jiang, Xiang Chen, Xinhua Xu, Wei-Min He. External electrolyte-free electrochemical one-pot cascade synthesis of 4-thiocyanato-1H-pyrazoles[J]. Chinese Chemical Letters, ;2023, 34(2): 107640. doi: 10.1016/j.cclet.2022.06.063 shu

External electrolyte-free electrochemical one-pot cascade synthesis of 4-thiocyanato-1H-pyrazoles

Wei-Bao He ^a ,
Sai-Jie Zhao ^a ,
Jing-Yang Chen ^b ,
Jun Jiang ^b ,
Xiang Chen ^b ,
Xinhua Xu ^{a, *,} ,
Wei-Min He ^{b, *,}

a.
College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China
b.
School of Chemistry and Chemical Engineering, University of South China, Hengyang 421001, China

xhx1581@hnu.edu.cn

weiminhe@usc.edu.cn

Received Date: 26 March 2022
Revised Date: 22 June 2022
Accepted Date: 23 June 2022
Available Online: 30 June 2022

Figures(5)

A practical synthetic method for 4-thiocyanato-1H-pyrazoles through the electrochemical cascade reaction of hydrazines, 1, 3-diones and NH₄SCN under metal-, chemical oxidant- and external electrolyte-free conditions was established. Importantly, both a gram-scale synthesis of 4-thiocyanato-1H-pyrazoles and five one-pot sequential transformations starting from hydrazine were successfully accomplished.
- Green chemistry,
- Electrochemistry,
- Cascade reaction,
- Multicomponent reaction,
- Thiocyanato
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