Citation: Jinjian Hu, Yufen Zhao, Yanmei Li. Rationally designed amyloid inhibitors based on amyloid-related structural studies[J]. Chinese Chemical Letters, ;2023, 34(2): 107623. doi: 10.1016/j.cclet.2022.06.046 shu

Rationally designed amyloid inhibitors based on amyloid-related structural studies

Jinjian Hu ^a ,
Yufen Zhao ^{a, d} ,
Yanmei Li ^{a, b, c, *,}

a.
Department of Chemistry, Key Lab of Bioorganic Phosphorus Chemistry & Chemical Biology, Tsinghua University, Beijing 100084, China
b.
Beijing Institute for Brain Disorders, Beijing 100069, China
c.
Center for Synthetic and Systems Biology, Tsinghua University, Beijing 100084, China
d.
Institute of Drug Discovery Technology, Ningbo University, Ningbo 315221, China

liym@mail.tsinghua.edu.cn

Received Date: 20 March 2022
Revised Date: 15 June 2022
Accepted Date: 19 June 2022
Available Online: 24 June 2022

Figures(3)

Amyloid proteins correlate with a series of degenerative diseases. Targeting amyloid aggregation has remained a hot topic in therapeutic studies. Numerous inhibitors have been developed, but very few have been approved for marketing. Meanwhile, the growing knowledge of amyloid structural characteristics provides a basis for the rational design of inhibitors. Here we introduce the high-resolution structural findings of amyloid fibrils in recent years and discuss the reported strategies toward rationally designed inhibitors based on amyloid-related structural studies.
- Amyloid,
- Amyloid structure,
- Degenerative disease,
- Amyloid inhibitor,
- Rational design
1. [1]
  F. Chiti, C.M. Dobson, Annu. Rev. Biochem. 86 (2017) 27–68.
2. [2]
  I. Benilova, E. Karran, B. De Strooper, Nat. Neurosci. 15 (2012) 349–357.
3. [3]
  K. Tepper, J. Biernat, S. Kumar, et al., J. Biol. Chem. 289 (2014) 34389–34407.
4. [4]
  H.A. Lashuel, C.R. Overk, A. Oueslati, et al., Nat. Rev. Neurosci. 14 (2013) 38–48.
5. [5]
  G. Li, Y.M. Li, Prog. Chem. 32 (2020) 14–22.
6. [6]
  K.W. Tipping, P. van Oosten-Hawle, E.W. Hewitt, et al., Trends Biochem. Sci. 40 (2015) 719–727.
7. [7]
  M. Goedert, D.S. Eisenberg, R.A. Crowther, Annu. Rev. Neurosci. 40 (2017) 189–210.
8. [8]
  M. Hasegawa, T. Nonaka, M. Masuda-Suzukake, Pharmacol. Ther. 172 (2017) 22–33.
9. [9]
  X. Mao, M.T. Ou, S.S. Karuppagounder, et al., Science 353 (2016) aah3374.
10. [10]
  M.R. Ma, Z.W. Hu, Y.F. Zhao, et al., Sci. Rep. 6 (2016) 37130.
11. [11]
  Q.Q. Li, Y.Q. Liu, Y.Y. Luo, et al., Chem. Commun. 56 (2020) 5370–5373.
12. [12]
  Y.S. Eisele, C. Monteiro, C. Fearns, et al., Nat. Rev. Drug Discov. 14 (2015) 759–780.
13. [13]
  Q.Q. Li, T.T. Chu, Y.X. Chen, et al., Chin. J. Chem. 32 (2014) 964–968.
14. [14]
  A. Paul, B.D. Zhang, S. Mohapatra, et al., Front. Mol. Biosci. 6 (2019) 16.
15. [15]
  L. Urquhart, Nat. Rev. Drug Discov. 18 (2019) 575.
16. [16]
  G. Li, W.Y. Yang, W.H. Li, et al., Chemistry 26 (2020) 3499–3503.
17. [17]
  P. Maiti, G.L. Dunbar, Int. J. Mol. Sci. 19 (2018) 1637.
18. [18]
  W.H. Ji, Z.B. Xiao, G.Y. Liu, et al., Chin. Chem. Lett. 28 (2017) 1829–1834.
19. [19]
  V. Armiento, A. Spanopoulou, A. Kapurniotu, Angew. Chem. Int. Ed. 59 (2020) 3372–3384.
20. [20]
  D.S. Eisenberg, M.R. Sawaya, Annu. Rev. Biochem. 86 (2017) 69–95.
21. [21]
  D. Li, C. Liu, Biochemistry 59 (2020) 639–646.
22. [22]
  R. Tycko, Annu. Rev. Phys. Chem. 62 (2011) 279–299.
23. [23]
  X.C. Bai, G. McMullan, S.H. Scheres, Trends Biochem. Sci. 40 (2015) 49–57.
24. [24]
  J.P. Renaud, A. Chari, C. Ciferri, et al., Nat. Rev. Drug Discov. 17 (2018) 471–492.
25. [25]
  Y. Li, C. Zhao, F. Luo, et al., Cell Res. 28 (2018) 897–903.
26. [26]
  T. Qiu, Q. Liu, Y.X. Chen, et al., J. Pept. Sci. 21 (2015) 522–529.
27. [27]
  A.T. Petkova, R.D. Leapman, Z. Guo, et al., Science 307 (2005) 262–265.
28. [28]
  A.T. Petkova, W.M. Yau, R. Tycko, Biochemistry 45 (2006) 498–512.
29. [29]
  A.K. Paravastu, R.D. Leapman, W.M. Yau, et al., Proc. Natl. Acad. Sci. U. S. A. 105 (2008) 18349–18354.
30. [30]
  A.K. Schutz, T. Vagt, M. Huber, et al., Angew. Chem. Int. Ed. 54 (2015) 331–335.
31. [31]
  M.A. Walti, F. Ravotti, H. Arai, et al., Proc. Natl. Acad. Sci. U. S. A. 113 (2016) E4976–E4984.
32. [32]
  L. Jin, W.H. Wu, Q.Y. Li, et al., Nanoscale 3 (2011) 4746–4751.
33. [33]
  Y. Xiao, B. Ma, D. McElheny, et al., Nat. Struct. Mol. Biol. 22 (2015) 499–505.
34. [34]
  M.T. Colvin, R. Silvers, Q.Z. Ni, et al., J. Am. Chem. Soc. 138 (2016) 9663–9674.
35. [35]
  C. Sachse, C. Xu, K. Wieligmann, et al., J. Mol. Biol. 362 (2006) 347–354.
36. [36]
  C. Sachse, M. Fandrich, N. Grigorieff, Proc. Natl. Acad. Sci. U. S. A. 105 (2008) 7462–7466.
37. [37]
  M. Schmidt, C. Sachse, W. Richter, et al., Proc. Natl. Acad. Sci. U. S. A. 106 (2009) 19813–19818.
38. [38]
  R. Zhang, X. Hu, H. Khant, et al., Proc. Natl. Acad. Sci. U. S. A. 106 (2009) 4653–4658.
39. [39]
  M. Schmidt, A. Rohou, K. Lasker, et al., Proc. Natl. Acad. Sci. U. S. A. 112 (2015) 11858–11863.
40. [40]
  L. Gremer, D. Scholzel, C. Schenk, et al., Science 358 (2017) 116–119.
41. [41]
  M. Kollmer, W. Close, L. Funk, et al., Nat. Commun. 10 (2019) 4760.
42. [42]
  Y. Yang, D. Arseni, W. Zhang, et al., Science 375 (2022) 167–172.
43. [43]
  M.R. Sawaya, S. Sambashivan, R. Nelson, et al., Nature 447 (2007) 453–457.
44. [44]
  A. Savastano, G. Jaipuria, L. Andreas, et al., Sci. Rep. 10 (2020) 21210.
45. [45]
  O.C. Andronesi, M. von Bergen, J. Biernat, et al., J. Am. Chem. Soc. 130 (2008) 5922–5928.
46. [46]
  V. Daebel, S. Chinnathambi, J. Biernat, et al., J. Am. Chem. Soc. 134 (2012) 13982–13989.
47. [47]
  A.W.P. Fitzpatrick, B. Falcon, S. He, et al., Nature 547 (2017) 185–190.
48. [48]
  B. Falcon, W. Zhang, M. Schweighauser, et al., Acta Neuropathol. 136 (2018) 699–708.
49. [49]
  B. Falcon, W. Zhang, A.G. Murzin, et al., Nature 561 (2018) 137–140.
50. [50]
  B. Falcon, J. Zivanov, W. Zhang, et al., Nature 568 (2019) 420–423.
51. [51]
  W. Zhang, A. Tarutani, K.L. Newell, et al., Nature 580 (2020) 283–287.
52. [52]
  T. Arakhamia, C.E. Lee, Y. Carlomagno, et al., Cell 180 (2020) 633–644. e12.
53. [53]
  W. Zhang, B. Falcon, A.G. Murzin, et al., eLife 8 (2019) e43584.
54. [54]
  M.D. Tuttle, G. Comellas, A.J. Nieuwkoop, et al., Nat. Struct. Mol. Biol. 23 (2016) 409–415.
55. [55]
  G. Lv, A. Kumar, K. Giller, et al., J. Mol. Biol. 420 (2012) 99–111.
56. [56]
  J. Verasdonck, L. Bousset, J. Gath, et al., Biomol. NMR Assign. 10 (2016) 5–12.
57. [57]
  R. Guerrero-Ferreira, N.M. Taylor, D. Mona, et al., eLife 7 (2018) e36402.
58. [58]
  B. Li, P. Ge, K.A. Murray, et al., Nat. Commun. 9 (2018) 3609.
59. [59]
  R. Guerrero-Ferreira, N.M. Taylor, A.A. Arteni, et al., eLife 8 (2019) e48907.
60. [60]
  D.R. Boyer, B. Li, C. Sun, et al., Proc. Natl. Acad. Sci. U. S. A. 117 (2020) 3592–3602.
61. [61]
  K. Zhao, Y. Li, Z. Liu, et al., Nat. Commun. 11 (2020) 2643.
62. [62]
  D.R. Boyer, B. Li, C. Sun, et al., Nat. Struct. Mol. Biol. 26 (2019) 1044–1052.
63. [63]
  Y. Sun, S. Hou, K. Zhao, et al., Cell Res. 30 (2020) 360–362.
64. [64]
  K. Zhao, Y.J. Lim, Z. Liu, et al., Proc. Natl. Acad. Sci. U. S. A. 117 (2020) 20305–20315.
65. [65]
  S. Zhang, Y.Q. Liu, C. Jia, et al., Proc. Natl. Acad. Sci. U. S. A. 118 (2021) e2011196118.
66. [66]
  M. Schweighauser, Y. Shi, A. Tarutani, et al., Nature 585 (2020) 464–469.
67. [67]
  Y.S. Fang, K.J. Tsai, Y.J. Chang, et al., Nat. Commun. 5 (2014) 4824.
68. [68]
  E.B. Lee, V.M. Lee, J.Q. Trojanowski, Nat. Rev. Neurosci. 13 (2011) 38–50.
69. [69]
  E.L. Guenther, Q. Cao, H. Trinh, et al., Nat. Struct. Mol. Biol. 25 (2018) 463–471.
70. [70]
  Z. Chang, J. Deng, W. Zhao, et al., Biochem. Biophys. Res. Commun. 532 (2020) 655–661.
71. [71]
  Q. Cao, D.R. Boyer, M.R. Sawaya, et al., Nat. Struct. Mol. Biol. 26 (2019) 619–627.
72. [72]
  Q. Li, W.M. Babinchak, W.K. Surewicz, Nat. Commun. 12 (2021) 1620.
73. [73]
  J. Shenoy, N. El Mammeri, A. Dutour, et al., FEBS J. 287 (2020) 2449–2467.
74. [74]
  D. Arseni, M. Hasegawa, A.G. Murzin, et al., Nature 601 (2022) 139–143.
75. [75]
  E.H. Pilkington, E.N. Gurzov, A. Kakinen, et al., Sci. Rep. 6 (2016) 21274.
76. [76]
  P. Krotee, J.A. Rodriguez, M.R. Sawaya, et al., eLife 6 (2017) e19273.
77. [77]
  C.A. Jurgens, M.N. Toukatly, C.L. Fligner, et al., Am. J. Pathol. 178 (2011) 2632–2640.
78. [78]
  P. Liu, S. Zhang, M.S. Chen, et al., Chem. Commun. 48 (2012) 191–193.
79. [79]
  S. Luca, W.M. Yau, R. Leapman, et al., Biochemistry 46 (2007) 13505–13522.
80. [80]
  S. Bedrood, Y. Li, J.M. Isas, et al., J. Biol. Chem. 287 (2012) 5235–5241.
81. [81]
  Q. Cao, D.R. Boyer, M.R. Sawaya, et al., Nat. Struct. Mol. Biol. 27 (2020) 653–659.
82. [82]
  C. Roder, T. Kupreichyk, L. Gremer, et al., Nat. Struct. Mol. Biol. 27 (2020) 660–667.
83. [83]
  M.E. Oskarsson, J.F. Paulsson, S.W. Schultz, et al., Am. J. Pathol. 185 (2015) 834–846.
84. [84]
  C. Scheckel, A. Aguzzi, Nat. Rev. Genet. 19 (2018) 405–418.
85. [85]
  R. Riek, S. Hornemann, G. Wider, et al., Nature 382 (1996) 180–182.
86. [86]
  J.J. Helmus, K. Surewicz, P.S. Nadaud, et al., Proc. Natl. Acad. Sci. U. S. A. 105 (2008) 6284–6289.
87. [87]
  J.J. Helmus, K. Surewicz, W.K. Surewicz, et al., J. Am. Chem. Soc. 132 (2010) 2393–2403.
88. [88]
  T. Theint, P.S. Nadaud, D. Aucoin, et al., Nat. Commun. 8 (2017) 753.
89. [89]
  D. Aucoin, Y. Xia, T. Theint, et al., J. Struct. Biol. 206 (2019) 36–42.
90. [90]
  C. Glynn, M.R. Sawaya, P. Ge, et al., Nat. Struct. Mol. Biol. 27 (2020) 417–423.
91. [91]
  L.Q. Wang, K. Zhao, H.Y. Yuan, et al., Nat. Struct. Mol. Biol. 27 (2020) 598–602.
92. [92]
  Q. Li, C.P. Jaroniec, W.K. Surewicz, bioRxiv (2021), 10.1101/2021.08.10.455830.
93. [93]
  J.K. Choi, I. Cali, K. Surewicz, et al., Proc. Natl. Acad. Sci. U. S. A. 113 (2016) 13851–13856.
94. [94]
  S. Lovestam, F.A. Koh, B. van Knippenberg, et al., eLife 11 (2022) e76494.
95. [95]
  T. Yokoyama, M. Mizuguchi, J. Med. Chem. 63 (2020) 14228–14242.
96. [96]
  D.W. Baggett, A. Nath, Biochemistry 57 (2018) 6099–6107.
97. [97]
  G. Toth, S.J. Gardai, W. Zago, et al., PLoS One 9 (2014) e87133.
98. [98]
  M.M. Dedmon, K. Lindorff-Larsen, J. Christodoulou, et al., J. Am. Chem. Soc. 127 (2005) 476–477.
99. [99]
  N.I. Brodie, K.I. Popov, E.V. Petrotchenko, et al., PLoS Comput. Biol. 15 (2019) e1006859.
100. [100]
  K.I. Popov, K.A.T. Makepeace, E.V. Petrotchenko, et al., Structure 27 (2019) 1710–1715 e4.
101. [101]
  S.A. Sievers, J. Karanicolas, H.W. Chang, et al., Nature 475 (2011) 96–100.
102. [102]
  Q. Cheng, W. Qiang, J. Phys. Chem. B 121 (2017) 5544–5552.
103. [103]
  P. Krotee, S.L. Griner, M.R. Sawaya, et al., J. Biol. Chem. 293 (2018) 2888–2902.
104. [104]
  S.L. Griner, P. Seidler, J. Bowler, et al., eLife 8 (2019) e46924.
105. [105]
  P.M. Seidler, D.R. Boyer, J.A. Rodriguez, et al., Nat. Chem. 10 (2018) 170–176.
106. [106]
  P.M. Seidler, D.R. Boyer, K.A. Murray, et al., J. Biol. Chem. 294 (2019) 16451–16464.
107. [107]
  S. Sangwan, S. Sahay, K.A. Murray, et al., eLife 9 (2020) e46775.
108. [108]
  V.V. Shvadchak, K. Afitska, D.A. Yushchenko, Angew. Chem. Int. Ed. 57 (2018) 5690–5694.
109. [109]
  Y.A. Kyriukha, K. Afitska, A.S. Kurochka, et al., J. Med. Chem. 62 (2019) 10342–10351.
110. [110]
  K. Afitska, A. Priss, D.A. Yushchenko, et al., J. Mol. Biol. 432 (2020) 967–977.
111. [111]
  A. Priss, K. Afitska, M. Galkin, et al., J. Med. Chem. 64 (2021) 6827–6837.
112. [112]
  S. Vilar, G. Cozza, S. Moro, Curr. Top. Med. Chem. 8 (2008) 1555–1572.
113. [113]
  K. Hochdorffer, J. Marz-Berberich, L. Nagel-Steger, et al., J. Am. Chem. Soc. 133 (2011) 4348–4358.
114. [114]
  N.Q. Thai, N.H. Tseng, M.T. Vu, et al., J. Comput. Aided Mol. Des. 30 (2016) 639–650.
115. [115]
  A. Espargaro, T. Ginex, M.D. Vadell, et al., J. Nat. Prod. 80 (2017) 278–289.
116. [116]
  S. Hojati, A. Ghahghaei, M. Lagzian, J. Biomol. Struct. Dyn. 36 (2018) 2118–2130.
117. [117]
  S. Vittorio, I. Adornato, R. Gitto, et al., J. Enzym. Inhib. Med. Chem. 35 (2020) 1727–1735.
118. [118]
  P. Patel, K. Parmar, V.K. Vyas, et al., J. Mol. Graph. Model. 77 (2017) 295–310.
119. [119]
  J.H. Zhao, H.L. Liu, P. Elumalai, et al., J. Mol. Model. 19 (2013) 151–162.
120. [120]
  E.A. Mirecka, H. Shaykhalishahi, A. Gauhar, et al., Angew. Chem. Int. Ed. 53 (2014) 4227–4230.
121. [121]
  E.D. Agerschou, P. Flagmeier, T. Saridaki, et al., eLife 8 (2019) e46112.
122. [122]
  H. Shaykhalishahi, A. Gauhar, M.M. Wordehoff, et al., Angew. Chem. Int. Ed. 54 (2015) 8837–8840.
123. [123]
  E.D. Agerschou, V. Borgmann, M.M. Wordehoff, et al., Chem. Sci. 11 (2020) 11331–11337.
124. [124]
  A.A. Orr, H. Shaykhalishahi, E.A. Mirecka, et al., Comput. Chem. Eng. 116 (2018) 322–332.
125. [125]
  A. Jha, M.G. Kumar, H.N. Gopi, et al., Langmuir 34 (2018) 1591–1600.
126. [126]
  N. Ghosh, L.M. Kundu, Bioorg. Med. Chem. 33 (2021) 116017.
127. [127]
  S.M. Ulamec, D.J. Brockwell, S.E. Radford, Front. Neurosci. 14 (2020) 611285.
128. [128]
  S. Bieler, C. Soto, Curr. Drug Targets 5 (2004) 553–558.
129. [129]
  A. Francioso, P. Punzi, A. Boffi, et al., Bioorg. Med. Chem. 23 (2015) 1671–1683.
130. [130]
  P. Yang, C. Yang, K. Zhang, et al., Chin. Chem. Lett. 29 (2018) 1811–1814.
131. [131]
  S. Kwon, M. Iba, C. Kim, et al., Neurotherapeutics 17 (2020) 935–954.
132. [132]
  H. Zeng, Y. Qi, Z. Zhang, et al., Chin. Chem. Lett. 32 (2021) 1857–1868.
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2. [2]
  Liping Zhao , Xixi Guo , Zhimeng Zhang , Xi Lu , Qingxuan Zeng , Tianyun Fan , Xintong Zhang , Fenbei Chen , Mengyi Xu , Min Yuan , Zhenjun Li , Jiandong Jiang , Jing Pang , Xuefu You , Yanxiang Wang , Danqing Song . Novel berberine derivatives as adjuvants in the battle against Acinetobacter baumannii: A promising strategy for combating multi-drug resistance. Chinese Chemical Letters, 2024, 35(10): 109506-. doi: 10.1016/j.cclet.2024.109506
3. [3]
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4. [4]
  Xin Dong , Tianqi Chen , Jing Liang , Lei Wang , Huajie Wu , Zhijin Xu , Junhua Luo , Li-Na Li . Structure design of lead-free chiral-polar perovskites for sensitive self-powered X-ray detection. Chinese Journal of Structural Chemistry, 2024, 43(6): 100256-100256. doi: 10.1016/j.cjsc.2024.100256
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  Aolei Tan , Xiaoxiao Ma . Exploring the functional roles of small-molecule metabolites in disease research: Recent advancements in metabolomics. Chinese Chemical Letters, 2024, 35(8): 109276-. doi: 10.1016/j.cclet.2023.109276
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  Zhe-Han Yang , Jie Yin , Lei Xin , Yuanfang Li , Yijie Huang , Ruo Yuan , Ying Zhuo . Research advancement of DNA-based intelligent hydrogels: Manufacture, characteristics, application of disease diagnosis and treatment. Chinese Chemical Letters, 2024, 35(10): 109558-. doi: 10.1016/j.cclet.2024.109558
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13. [13]
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14. [14]
  Pingfan Zhang , Shihuan Hong , Ning Song , Zhonghui Han , Fei Ge , Gang Dai , Hongjun Dong , Chunmei Li . Alloy as advanced catalysts for electrocatalysis: From materials design to applications. Chinese Chemical Letters, 2024, 35(6): 109073-. doi: 10.1016/j.cclet.2023.109073
15. [15]
  Zikang Hu , Hengjie Zhang , Zhengqiu Li , Tianbao Zhao , Zhipeng Gu , Qijuan Yuan , Baoshu Chen . Multifunctional photothermal hydrogels: Design principles, various functions, and promising biological applications. Chinese Chemical Letters, 2024, 35(10): 109527-. doi: 10.1016/j.cclet.2024.109527
16. [16]
  Xiaoliu Liang , Chunliu Huang , Hui Liu , Hu Chen , Jiabao Shou , Hongwei Cheng , Gang Liu . Natural hydrogel dressings in wound care: Design, advances, and perspectives. Chinese Chemical Letters, 2024, 35(10): 109442-. doi: 10.1016/j.cclet.2023.109442
17. [17]
  Chao Ma , Cong Lin , Jian Li . MicroED as a powerful technique for the structure determination of complex porous materials. Chinese Journal of Structural Chemistry, 2024, 43(3): 100209-100209. doi: 10.1016/j.cjsc.2023.100209
18. [18]
  Yuhang Li , Yang Ling , Yanhang Ma . Application of three-dimensional electron diffraction in structure determination of zeolites. Chinese Journal of Structural Chemistry, 2024, 43(4): 100237-100237. doi: 10.1016/j.cjsc.2024.100237
19. [19]
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沈阳化工大学材料科学与工程学院沈阳 110142