Citation: Hu Chen, Minglei Teng, Hongrui Zhang, Xiaoliu Liang, Hongwei Cheng, Gang Liu. Advanced radionuclides in diagnosis and therapy for hepatocellular carcinoma[J]. Chinese Chemical Letters, ;2022, 33(7): 3371-3383. doi: 10.1016/j.cclet.2022.03.079 shu

Advanced radionuclides in diagnosis and therapy for hepatocellular carcinoma

State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics, Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen 361005, China

hongwei1026@hotmail.com

gangliu.cmitm@xmu.edu.cn

Received Date: 3 February 2022
Revised Date: 17 March 2022
Accepted Date: 17 March 2022
Available Online: 21 March 2022

Figures(4)

Hepatocellular carcinoma (HCC) is the most common primary malignant tumor of the liver, but early diagnosis and effective treatment are still difficult. With the development of radionuclide applications in medicine, nuclear medicine is playing an increasingly important role in the diagnosis and treatment of HCC. Radionuclide-based positron emission tomography-computed tomography and single-photon emission computed tomography-computed tomography molecular imaging are indispensable for assessing progression, staging, differentiation, preoperative planning, postoperative prediction, and evaluation of HCC in clinical applications. Moreover, radionuclide-based endoradiotherapy provides an objective therapeutic strategy for patients with unresectable advanced HCC. This review highlights the application and development of radionuclides in the diagnosis and treatment of HCC. More efforts are warranted for the development of advanced radionuclides to make significant contributions in the treatment of HCC.
- Radionuclide,
- Hepatocellular carcinoma,
- Diagnostic imaging,
- Endoradiotherapy,
- Precise medicine
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沈阳化工大学材料科学与工程学院沈阳 110142