Citation: Yingying Song, Chang-Ming Dong. Sugar-dependent targeting and immune adjuvant effects of hyperbranched glycosylated polypeptide nanoparticles for ovalbumin delivery[J]. Chinese Chemical Letters, ;2022, 33(8): 4084-4088. doi: 10.1016/j.cclet.2022.01.051 shu

Sugar-dependent targeting and immune adjuvant effects of hyperbranched glycosylated polypeptide nanoparticles for ovalbumin delivery

Yingying Song ,
Chang-Ming Dong ^*,

School of Chemistry and Chemical Engineering, Shanghai Key Laboratory of Electrical Insulation and Thermal Aging, Shanghai Jiao Tong University, Shanghai 200240, China

cmdong@sjtu.edu.cn

Received Date: 24 August 2021
Revised Date: 14 January 2022
Accepted Date: 17 January 2022
Available Online: 23 January 2022

Figures(4)

Sugar-dependent targeting and immune adjuvant effects of hyperbranched glycosylated polypeptide nanoparticles were disclosed for ovalbumin (OVA) delivery system. The mannose-coated polypeptide nanoparticles can induce strongest targeting and immune adjuvant effects to macrophages than those glucose/lactose-coated ones, which effectively transported OVA into cells and facilitated OVA subcellular escape from endolysosomes into cytoplasm with the assistance of UV irradiation or intracellular acidic pH.
- Polypeptide nanoparticles,
- Sugar targeting,
- Immune adjuvant,
- Ovalbumin delivery system
1. [1]
  C.N. Fries, E.J. Curvino, J.L. Chen, et al., Nat. Nanotechnol. 16 (2021) 1–14.
2. [2]
  C.W. Shields Ⅳ, L.L.W. Wang, M.A. Evans, et al., Adv. Mater. 32 (2020) 1901633. doi: 10.1002/adma.201901633
3. [3]
  K.T. Magar, G.F. Boafo, X. Li, et al., Chin. Chem. Lett. 33 (2022) 587–596. doi: 10.1016/j.cclet.2021.08.020
4. [4]
  Y. Hu, L. Lin, Z. Guo, et al., Chin. Chem. Lett. 32 (2021) 1770–1774. doi: 10.1016/j.cclet.2020.12.055
5. [5]
  Y.W. Lee, D.C. Luther, R. Goswami, et al., J. Am. Chem. Soc. 142 (2020) 4349–4355. doi: 10.1021/jacs.9b12759
6. [6]
  L. Ren, J. Lv, H. Wang, et al., Angew. Chem. Int. Ed. 59 (2020) 4711–4719. doi: 10.1002/anie.201914970
7. [7]
  A.R. Mazo, S. Allison-Logan, F. Karimi, et al., Chem. Soc. Rev. 49 (2020) 4737–4834. doi: 10.1039/C9CS00738E
8. [8]
  Z. Song, Z. Tan, J. Cheng, Macromolecules 52 (2019) 8521–8539. doi: 10.1021/acs.macromol.9b01450
9. [9]
  E. Liaroua, S. Varlas, D. Skoulas, et al., Prog. Polym. Sci. 83 (2018) 28–78. doi: 10.1016/j.progpolymsci.2018.05.001
10. [10]
  X. Liu, W. Gao, Angew. Chem. Int. Ed. 60 (2021) 11024–11035. doi: 10.1002/anie.202003708
11. [11]
  Y. Miura, J. Mater. Chem. B 8 (2020) 2010–2019. doi: 10.1039/C9TB02418B
12. [12]
  L. Li, Z. Yang, X. Chen, Acc. Chem. Res. 53 (2020) 2044–2054. doi: 10.1021/acs.accounts.0c00334
13. [13]
  Z.S. Clauss, J.R. Kramer, Adv. Drug Deliver. Rev. 169 (2021) 152–167. doi: 10.1016/j.addr.2020.12.009
14. [14]
  L. Zeng, Z. Liao, W. Li, et al., Chin. Chem. Lett. 31 (2020) 1162–1164. doi: 10.1016/j.cclet.2019.10.015
15. [15]
  B. Mondal, B. Pandey, N. Parekh, et al., Biomater. Sci. 8 (2020) 6322–6336. doi: 10.1039/D0BM01469A
16. [16]
  Z. Wang, Q. Chen, H. Zhu, et al., Chin. Chem. Lett. 32 (2021) 1888–1892. doi: 10.1016/j.cclet.2021.01.036
17. [17]
  M.N. Zhou, C.S. Delaveris, J.R. Kramer, et al., Angew. Chem. Int. Ed. 57 (2018) 3137–3142. doi: 10.1002/anie.201713075
18. [18]
  Y. Song, Y. Chen, P. Li, et al., Biomacromolecules 21 (2020) 5345–5357. doi: 10.1021/acs.biomac.0c01465
19. [19]
  D.S. Wilson, S. Hirosue, M.M. Raczy, et al., Nat. Mater. 18 (2019) 175–185. doi: 10.1038/s41563-018-0256-5
20. [20]
  J. Conniot, A. Scomparin, C. Peres, et al., Nat. Nanotechnol. 14 (2019) 891–901. doi: 10.1038/s41565-019-0512-0
21. [21]
  J.T. Wilson, Science 363 (2019) 584–585. doi: 10.1126/science.aav9000
22. [22]
  W.J. Qi, Y.F. Zhang, J. Wang, et al., J. Am. Chem. Soc. 140 (2018) 8851–8857. doi: 10.1021/jacs.8b04731
23. [23]
  L. Yu, R. Feng, L. Zhu, et al., Sci. Adv. 6 (2020) eabb6595. doi: 10.1126/sciadv.abb6595
24. [24]
  P. Li, Y.Y. Song, C.M. Dong, Polym. Chem. 9 (2018) 3974–3986. doi: 10.1039/C8PY00641E
25. [25]
  Z. Tian, M. Wang, A.Y. Zhang, et al., Polymer (Guildf) 49 (2008) 446–454. doi: 10.1016/j.polymer.2007.11.048
26. [26]
  C.A. Machado, I.R. Smith, D.A. Savin, Macromolecules 52 (2019) 1899–1911. doi: 10.1021/acs.macromol.8b02043
27. [27]
  T. Mosaiab, D.C. Farr, M.J. Kiefel, et al., Adv. Drug Deliv. Rev. 151 (2019) 94–129.
28. [28]
  Z. Huang, J. Gan, Z. Long, et al., Biomaterials 90 (2016) 72–84. doi: 10.1016/j.biomaterials.2016.03.009
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2. [2]
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4. [4]
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5. [5]
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8. [8]
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9. [9]
  Shaoqing Du , Xinyong Liu , Xueping Hu , Peng Zhan . Targeting novel sites represents an effective strategy for combating drug resistance. Chinese Chemical Letters, 2025, 36(1): 110378-. doi: 10.1016/j.cclet.2024.110378
10. [10]
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11. [11]
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12. [12]
  Yanfei Liu , Yaqin Hu , Yifu Tan , Qiwen Chen , Zhenbao Liu . Tumor acidic microenvironment activatable DNA nanostructure for precise cancer cell targeting and inhibition. Chinese Chemical Letters, 2025, 36(1): 110289-. doi: 10.1016/j.cclet.2024.110289
13. [13]
  Cheng-Zhe Gao , Hao-Ran Jia , Tian-Yu Wang , Xiao-Yu Zhu , Xiaofeng Han , Fu-Gen Wu . A dual drug-loaded tumor vasculature-targeting liposome for tumor vasculature disruption and hypoxia-enhanced chemotherapy. Chinese Chemical Letters, 2025, 36(1): 109840-. doi: 10.1016/j.cclet.2024.109840
14. [14]
  Bharathi Natarajan , Palanisamy Kannan , Longhua Guo . Metallic nanoparticles for visual sensing: Design, mechanism, and application. Chinese Journal of Structural Chemistry, 2024, 43(9): 100349-100349. doi: 10.1016/j.cjsc.2024.100349
15. [15]
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16. [16]
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17. [17]
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18. [18]
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20. [20]
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