Citation: Yan Zhang, Xianzhi Hu, Qingjiang Wang, Yi Zhang. Recent advances in microchip-based methods for the detection of pathogenic bacteria[J]. Chinese Chemical Letters, ;2022, 33(6): 2817-2831. doi: 10.1016/j.cclet.2021.11.033 shu

Recent advances in microchip-based methods for the detection of pathogenic bacteria

Yan Zhang ^{a, *,} ,
Xianzhi Hu ^{a, *,} ,
Qingjiang Wang ^b ,
Yi Zhang ^c

a.
Faculty of Science, Kunming University of Science and Technology, Kunming 650500, China
b.
School of Chemistry and Molecular Engineering, East China Normal University, Shanghai 200241, China
c.
College of Chemistry and Chemical Engineering, Kunming University, Kunming 650214, China

zhangyan_ecnu@163.com

xianzhihu2@sina.com

Received Date: 9 September 2021
Revised Date: 9 October 2021
Accepted Date: 8 November 2021
Available Online: 13 November 2021

Figures(17)

Pathogenic bacteria pose a global threat to public health and attract considerable attention in terms of food safety. Rapid and highly sensitive strategies for detecting pathogenic bacteria must be urgently developed to ensure food safety and public health. Microchips offer significant advantages for pathogenic bacterial detection in terms of speed and sensitivity compared with those of traditional techniques. Microfluidic devices, in particular, have attracted significant attention for the detection of pathogenic bacteria owing to their ease of operation, high throughput, cost-effectiveness, and high sensitivity. This review summarizes representative articles on the analysis of pathogenic bacteria using microchip-based systems. A detailed and comprehensive overview of microchip-based techniques for the detection of pathogenic bacteria is presented herein, and their advantages and disadvantages are discussed to compare their applications. The accomplishments and shortcomings of these microchips have been highlighted, and the direction of development and prospects of the analysis of pathogenic bacteria have been examined. The content of this review is anticipated to provide constructive suggestions for further development of highly effective and advanced microchip-based strategies for detecting pathogenic bacteria.
- Microchip,
- Pathogenic bacteria,
- Aptamer,
- Probe-lengthening amplification,
- Loop-mediated isothermal amplification,
- Polymerase chain reaction
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沈阳化工大学材料科学与工程学院沈阳 110142