Citation: Wenjie Zhou, Zhe Hu, Jinxin Wei, Hanqing Dai, Yuanyuan Chen, Siyu Liu, Zhongtao Duan, Fengxian Xie, Wanlu Zhang, Ruiqian Guo. Quantum dots-hydrogel composites for biomedical applications[J]. Chinese Chemical Letters, ;2022, 33(3): 1245-1253. doi: 10.1016/j.cclet.2021.09.027 shu

Quantum dots-hydrogel composites for biomedical applications

Wenjie Zhou ^{a, 1} ,
Zhe Hu ^{a, 1} ,
Jinxin Wei ^a ,
Hanqing Dai ^b ,
Yuanyuan Chen ^a ,
Siyu Liu ^b ,
Zhongtao Duan ^b ,
Fengxian Xie ^a ,
Wanlu Zhang ^{a, *,} ,
Ruiqian Guo ^{a, b, c, d, *,}

a.
Institute for Electric Light Sources, School of Information Science and Technology, Fudan University, Shanghai 200433, China
b.
Institute of Future Lighting, Academy for Engineering and Technology, Fudan University, Shanghai 200433, China
c.
Zhongshan-Fudan Joint Innovation Center, Zhongshan 528437, China
d.
Yiwu Research Institute of Fudan University, Yiwu 322000, China

fdwlzhang@fudan.edu.cn

rqguo@fudan.edu.cn

Received Date: 13 May 2021
Revised Date: 4 September 2021
Accepted Date: 6 September 2021
Available Online: 10 September 2021

Figures(12)

Quantum dots-hydrogel composites are promising new materials that have attracted extensive attention due to their incomparable biocompatibility and acceptable biodegradability, leading to enormous potential applications for various fields. This review summarizes the recent advances in quantum dots-hydrogel composites with a focus on synthesis methods, including hydrogel gelation in quantum dots (QDs) solution, embedding prepared QDs into hydrogels after gelation, forming QDs in situ within the preformed gel and cross-linking via QDs to form hydrogels. In particularly, biomedical applications as bioimaging, biosensing and drug delivery are also reviewed, followed by a discussion on the inherent challenges of design optimization, biocompatibility and bimodal applications and the prospect of the future development. These results will guide the development of quantum dots-hydrogel composites and provide critical insights to inspire researchers in future.
- Quantum dots,
- Hydrogels,
- Bioimaging,
- Biosensing,
- Drug delivery
1. [1]
  K.H. Bae, M. Kurisawa, Biomater. Sci. 4 (2016) 1184-1192. doi: 10.1039/C6BM00330C
2. [2]
  N. Mehwish, X. Dou, Y. Zhao, C. Feng, Mater. Horiz. 6 (2019) 14-44. doi: 10.1039/c8mh01130c
3. [3]
  Y.Q. Li, D.J. Young, X.J. Loh, Mater. Chem. Front. 3 (2019) 1489-1502. doi: 10.1039/c9qm00127a
4. [4]
  A. Jayakumar, V.K. Jose, J.M. Lee, Small Methods 4 (2020) 1900735. doi: 10.1002/smtd.201900735
5. [5]
  H. Dai, Y. Chen, W. Dai, et al., Adv. Mater. 33 (2021) 2101239. doi: 10.1002/adma.202101239
6. [6]
  M. Hasanzadeh, N. Shadjou, M. de la Guardia, TrAC Trends Anal. Chem. 102 (2018) 210-224. doi: 10.1016/j.trac.2018.02.011
7. [7]
  M. Chan, A. Almutairi, Mater. Horiz. 3 (2016) 21-40. doi: 10.1039/C5MH00161G
8. [8]
  L. Yu, J.D. Ding, Chem. Soc. Rev. 37 (2008) 1473-1481. doi: 10.1039/b713009k
9. [9]
  J. Shi, Z. Shi, Y. Dong, F. Wu, D. Liu, ACS Appl. Bio Mater. 3 (2020) 2827-2837. doi: 10.1021/acsabm.0c00081
10. [10]
  S. Park, K.M. Park, Polymers 8 (2016) 8010023.
11. [11]
  O. Wichterle, D. Lim, Nature 185 (1960) 117-118. doi: 10.1038/185117a0
12. [12]
  H. Dai, Y. Chen, W. Dai, et al., Adv. Mater. Technol. 6 (2021) 2000848. doi: 10.1002/admt.202000848
13. [13]
  D. Gan, T. Xu, W. Xing, et al., Adv. Funct. Mater. 29 (2019) 1805964. doi: 10.1002/adfm.201805964
14. [14]
  L. Han, X. Lu, K. Liu, et al., ACS Nano 11 (2017) 2561-2574. doi: 10.1021/acsnano.6b05318
15. [15]
  C. Ma, W. Lu, X. Yang, et al., Adv. Funct. Mater. 28 (2018) 1704568. doi: 10.1002/adfm.201704568
16. [16]
  C. Li, S. Zheng, C. Du, et al., ACS Appl. Polym. Mater. 2 (2020) 1043-1052. doi: 10.1021/acsapm.9b00971
17. [17]
  T.H. Kim, J. Seo, S.J. Lee, et al., Chem. Mater. 19 (2007) 5815-5817. doi: 10.1021/cm701880e
18. [18]
  H. Cai, P. Yao, Nanoscale 5 (2013) 2892-2900. doi: 10.1039/c3nr00178d
19. [19]
  P. Thoniyot, M.J. Tan, A.A. Karim, D.J. Young, X.J. Loh, Adv. Sci. 2 (2015) 1400010. doi: 10.1002/advs.201400010
20. [20]
  K. Lei, Q. Ma, L. Yu, J. Ding, J. Mater. Chem. B 4 (2016) 7793-7812. doi: 10.1039/C6TB02019D
21. [21]
  B. Sui, Y. Li, B. Yang, Chin. Chem. Lett. 31 (2020) 1443-1447. doi: 10.1016/j.cclet.2019.08.023
22. [22]
  J. Bai, J. Chu, X. Yin, et al., Chem. Eng. J. 391 (2020) 123553. doi: 10.1016/j.cej.2019.123553
23. [23]
  A.J. Sutherland, Curr. Opin. Solid ST. M. 6 (2002) 365-370. doi: 10.1016/S1359-0286(02)00081-5
24. [24]
  K. Kalyanasundaram, E. Borgarello, D. Duonghong, M. Gratzel, Angew. Chem. Int. Ed. 20 (1981) 987-988. doi: 10.1002/anie.198109871
25. [25]
  Z. Hu, H. Dai, X. Wei, et al., RSC Adv. 10 (2020) 17266-17269. doi: 10.1039/d0ra02778b
26. [26]
  W. Zhang, X. Zhou, X. Zhong, Inorg. Chem. 51 (2012) 3579-3587. doi: 10.1021/ic2024023
27. [27]
  R. Zeng, R. Shen, Y. Zhao, et al., Nanotechnology 25 (2014) 135602. doi: 10.1088/0957-4484/25/13/135602
28. [28]
  J. Wei, Z. Hu, W. Zhou, et al., J. Colloid Interface Sci. 602 (2021) 307-315. doi: 10.1016/j.jcis.2021.05.110
29. [29]
  B. Wang, J. Li, Z. Tang, B. Yang, S. Lu, Sci. Bull. 64 (2019) 1285-1292. doi: 10.1016/j.scib.2019.07.021
30. [30]
  S. Lu, L. Sui, J. Liu, et al., Adv. Mater. 29 (2017) 1603443. doi: 10.1002/adma.201603443
31. [31]
  W. Li, Y. Liu, B. Wang, et al., Chin. Chem. Lett. 30 (2019) 2323-2327. doi: 10.1016/j.cclet.2019.06.040
32. [32]
  J. Yang, M. Yao, L. Wen, et al., Nanoscale 6 (2014) 11282-11292. doi: 10.1039/C4NR03058C
33. [33]
  J. Zhang, J. Jin, J. Wan, et al., Chem. Eng. J. 408 (2021) 127351. doi: 10.1016/j.cej.2020.127351
34. [34]
  A. Nair, J. Shen, P. Thevenot, et al., Nanotechnology 19 (2008) 485102. doi: 10.1088/0957-4484/19/48/485102
35. [35]
  L. Zhou, F. Zhang, Mater. Sci. Eng. C 31 (2011) 1429-1435. doi: 10.1016/j.msec.2011.05.010
36. [36]
  J. Yuan, D. Wen, N. Gaponik, A. Eychmuller, Angew. Chem. Int. Ed. 52 (2013) 976-979. doi: 10.1002/anie.201205791
37. [37]
  L. Zhang, S.R. Jean, S. Ahmed, et al., Nat. Commun. 8 (2017) 381. doi: 10.1038/s41467-017-00298-w
38. [38]
  C. Lee, B. Pant, B.S. Kim, et al., Mater. Lett. 207 (2017) 57-61. doi: 10.1016/j.matlet.2017.07.058
39. [39]
  L. Ai, Y. Yang, B. Wang, et al., Sci. Bull. 66 (2021) 839-856. doi: 10.1016/j.scib.2020.12.015
40. [40]
  K. Deligkaris, T.S. Tadele, W. Olthuis, A. van den Berg, Sens. Actuators B: Chem. 147 (2010) 765-774. doi: 10.1016/j.snb.2010.03.083
41. [41]
  C. Liu, F. Li, J. Yang, F. Tian, J. Sun, J. Control. Release 213 (2015) E16-E17.
42. [42]
  B.W. Garner, T. Cai, Z.B. Hu, A. Neogi, Opt. Express 16 (2008) 19410-19418. doi: 10.1364/OE.16.019410
43. [43]
  M. Hu, X.Y. Gu, Y. Hu, Y.H. Deng, C.Y. Wang, Macromol. Mater. Eng. 301 (2016) 1352-1362. doi: 10.1002/mame.201600248
44. [44]
  S.A. Park, E. Jang, W.G. Koh, B. Kim, Talanta 84 (2011) 1000-1003. doi: 10.1016/j.talanta.2011.02.021
45. [45]
  J. Zhou, H. Li, ACS Appl. Mater. Interfaces 4 (2012) 721-724. doi: 10.1021/am201624u
46. [46]
  J.H. Holtz, S.A. Asher, Nature 389 (1997) 829-832. doi: 10.1038/39834
47. [47]
  A. Martin-Pacheco, A.E. Del Rio Castillo, C. Martin, et al., ACS Appl. Mater. Interfaces 10 (2018) 18192-18201. doi: 10.1021/acsami.8b02162
48. [48]
  J. Yang, S. Zhao, R. Jin, et al., Macromol. Mater. Eng. 304 (2019) 1800658. doi: 10.1002/mame.201800658
49. [49]
  N. Sahiner, K. Sel, K. Meral, et al., Colloids Surf. A 389 (2011) 6-11. doi: 10.1016/j.colsurfa.2011.09.006
50. [50]
  T. Yang, Q. Li, W. Wen, et al., Radiat. Phys. Chem. 145 (2018) 130-134. doi: 10.1016/j.radphyschem.2017.10.012
51. [51]
  S. Nayak, S.R. Prasad, D. Mandal, P. Das, ACS Appl. Bio Mater. 3 (2020) 7865-7875. doi: 10.1021/acsabm.0c01022
52. [52]
  W. Wu, J. Shen, P. Banerjee, S. Zhou, Biomaterials 31 (2010) 8371-8381. doi: 10.1016/j.biomaterials.2010.07.061
53. [53]
  W. Wu, M. Aiello, T. Zhou, A. Berliner, P. Banerjee, S. Zhou, Biomaterials 31 (2010) 3023-3031. doi: 10.1016/j.biomaterials.2010.01.011
54. [54]
  J.H. Yoo, S.W. Lee, J. Nanosci. Nanotechnol. 14 (2014) 7648-7653. doi: 10.1166/jnn.2014.9411
55. [55]
  B. Ryplida, I. In, S.Y. Park, ACS Appl. Mater. Interfaces 12 (2020) 51766-51775. doi: 10.1021/acsami.0c16745
56. [56]
  N. Gogoi, M. Barooah, G. Majumdar, D. Chowdhury, ACS Appl. Mater. Interfaces 7 (2015) 3058-3067. doi: 10.1021/am506558d
57. [57]
  S. Bhattacharya, R. Sarkar, S. Nandi, A. Porgador, R. Jelinek, Anal. Chem. 89 (2017) 830-836. doi: 10.1021/acs.analchem.6b03749
58. [58]
  P.K. Pandey, Preeti, K. Rawat, T. Prasad, H.B. Bohidar, J. Mater Chem. B 8 (2020) 1277-1289. doi: 10.1039/c9tb01863h
59. [59]
  H.I. Park, S.Y. Park, ACS Appl. Mater. Interfaces 10 (2018) 30172-30179. doi: 10.1021/acsami.8b10768
60. [60]
  M. Chen, C. Grazon, P. Sensharma, et al., ACS Appl. Mater. Interfaces 12 (2020) 43513-43521. doi: 10.1021/acsami.0c13489
61. [61]
  X. Zhang, S. Ding, S. Cao, A. Zhu, G. Shi, Biosens. Bioelectron. 80 (2016) 315-322. doi: 10.1016/j.bios.2016.01.083
62. [62]
  S. Mohammadi, S. Mohammadi, A. Salimi, Talanta 224 (2021) 121895. doi: 10.1016/j.talanta.2020.121895
63. [63]
  Y. Zhao, X. Zhao, B. Tang, et al., Adv. Funct. Mater. 20 (2010) 976-982. doi: 10.1002/adfm.200901812
64. [64]
  C. Ruiz-Palomero, S. Benitez-Martinez, M.L. Soriano, M. Valcarcel, Anal. Chim. Acta 974 (2017) 93-99. doi: 10.1016/j.aca.2017.04.018
65. [65]
  J.H. Kim, S.Y. Lim, D.H. Nam, et al., Biosens. Bioelectron. 26 (2011) 1860-1865. doi: 10.1016/j.bios.2010.01.026
66. [66]
  R. Abbel, R. van der Weegen, W. Pisula, et al., Chem. Eur. J. 15 (2009) 9737-9746. doi: 10.1002/chem.200900620
67. [67]
  Y. Wang, Y. Xue, J. Wang, et al., J. Polym. Res. 26 (2019)248. doi: 10.1111/brv.12452
68. [68]
  N.S. Rejinold, K.P. Chennazhi, H. Tamura, S.V. Nair, J. Rangasamy, ACS Appl. Mater. Interfaces. 3 (2011) 3654-3665. doi: 10.1021/am200844m
69. [69]
  D. Zhao, W. Ma, R. Wang, et al., Polymers 11 (2019)1171. doi: 10.3390/polym11071171
70. [70]
  Y. Liu, J. Yang, P. Zhang, C. Liu, W. Wang, W. Liu, J. Mater. Chem. 22 (2012) 512-519. doi: 10.1039/C1JM13063C
71. [71]
  L. Wang, B. Li, F. Xu, et al., Biomaterials 145 (2017) 192-206. doi: 10.1016/j.biomaterials.2017.08.039
72. [72]
  J. Shen, L. Xu, Y. Lu, et al., Int. J. Pharm. 427 (2012) 400-409. doi: 10.1016/j.ijpharm.2012.01.059
73. [73]
  R. Jin, X. Yang, D. Zhao, et al., Nanoscale 11 (2019) 16080-16091. doi: 10.1039/c9nr04630e
74. [74]
  H. Lu, L. Lv, J. Ma, et al., J. Mech. Behav. Biomed. Mater. 88 (2018) 261-269. doi: 10.1016/j.jmbbm.2018.08.024
75. [75]
  N. Sarkar, G. Sahoo, R. Das, G. Prusty, S.K. Swain, Eur. J. Pharm. Sci. 109 (2017) 359-371. doi: 10.1016/j.ejps.2017.08.015
76. [76]
  S. Javanbakht, H. Namazi, Mater. Sci. Eng. C 87 (2018) 50-59. doi: 10.1016/j.msec.2018.02.010
77. [77]
  S. Singh, A. Mishra, R. Kumari, et al., Carbon 114 (2017) 169-176. doi: 10.1016/j.carbon.2016.12.020
78. [78]
  Y. Xiang, C. Mao, X. Liu, et al., Small 15 (2019) 1900322. doi: 10.1002/smll.201900322
79. [79]
  A.P. Alivisatos, Science 271 (1996) 933-937. doi: 10.1126/science.271.5251.933
80. [80]
  Y. Zhao, R. Yang, W. Wan, et al., Chem. Eng. J. 389 (2020) 124453. doi: 10.1016/j.cej.2020.124453
81. [81]
  X. Wang, X. Li, N. Chen, et al., NPJ Comput. Mater. 31 (2020) 6. doi: 10.1117/12.2574024
82. [82]
  F. Mekki-Berrada, Z. Ren, T. Huang, et al., NPJ Comput. Mater. 7 (2021) 55. doi: 10.1038/s41524-021-00520-w
83. [83]
  N. Marzari, A. Ferretti, C. Wolverton, Nat. Mater. 20 (2021) 736-749. doi: 10.1038/s41563-021-01013-3
84. [84]
  S.G. Louie, Y.H. Chan, F.H. da Jornada, Z. Li, D. Qiu, Nat. Mater. 20 (2021) 728-735. doi: 10.1038/s41563-021-01015-1
85. [85]
  C.E. Bradburne, J.B. Delehanty, K.B. Gemmill, et al., Bioconjugate Chem. 24 (2013) 1570-1583. doi: 10.1021/bc4001917
86. [86]
  M.T. Hasan, B.H. Lee, C.W. Lin, et al., 2D Mater. 8 (2021) 035013. doi: 10.1088/2053-1583/abe4e3
87. [87]
  M.A. Krishnan, K. Yadav, P. Roach, V. Chelvam, Biomater. Sci. 9 (2021) 2295-2312. doi: 10.1039/D0BM01970D
88. [88]
  X. Dong, H. Zhao, Y. Mi, et al., Chin. Chem. Lett. 31 (2020) 1616-1619. doi: 10.1016/j.cclet.2019.11.010
89. [89]
  D. Zhao, J. Yang, R. Xia, et al., Chem. Commun. 54 (2018) 527-530. doi: 10.1039/C7CC09266K
90. [90]
  J. Zhang, C. Hu, B. Zhang, Nanomedicine 12 (2016) 505-505.
91. [91]
  Y. Yang, L. Lin, L. Jing, X. Yue, Z. Dai, ACS Appl. Mater. Interfaces 9 (2017) 23450-23457. doi: 10.1021/acsami.7b05867
1. [1]
  Shu-Ran Xu , Fang-Xing Xiao . Metal halide perovskites quantum dots: Synthesis, and modification strategies for solar CO2 conversion. Chinese Journal of Structural Chemistry, 2023, 42(12): 100173-100173. doi: 10.1016/j.cjsc.2023.100173
2. [2]
  Jiajia Wang , XinXin Ge , Yajing Xiang , Xiaoliang Qi , Ying Li , Hangbin Xu , Erya Cai , Chaofan Zhang , Yulong Lan , Xiaojing Chen , Yizuo Shi , Zhangping Li , Jianliang Shen . An ionic liquid functionalized sericin hydrogel for drug-resistant bacteria-infected diabetic wound healing. Chinese Chemical Letters, 2025, 36(2): 109819-. doi: 10.1016/j.cclet.2024.109819
3. [3]
  Linghui Zou , Meng Cheng , Kaili Hu , Jianfang Feng , Liangxing Tu . Vesicular drug delivery systems for oral absorption enhancement. Chinese Chemical Letters, 2024, 35(7): 109129-. doi: 10.1016/j.cclet.2023.109129
4. [4]
  Benjian Xin , Rui Wang , Lili Liu , Zhiqiang Niu . Metal-organic framework derived MnO@C/CNTs composite for high-rate lithium-based semi-solid flow batteries. Chinese Journal of Structural Chemistry, 2023, 42(11): 100116-100116. doi: 10.1016/j.cjsc.2023.100116
5. [5]
  Hao Deng , Yuxin Hui , Chao Zhang , Qi Zhou , Qiang Li , Hao Du , Derek Hao , Guoxiang Yang , Qi Wang . MXene−derived quantum dots based photocatalysts: Synthesis, application, prospects, and challenges. Chinese Chemical Letters, 2024, 35(6): 109078-. doi: 10.1016/j.cclet.2023.109078
6. [6]
  Zhilong Xie , Guohui Zhang , Ya Meng , Yefei Tong , Jian Deng , Honghui Li , Qingqing Ma , Shisong Han , Wenjun Ni . A natural nano-platform: Advances in drug delivery system with recombinant high-density lipoprotein. Chinese Chemical Letters, 2024, 35(11): 109584-. doi: 10.1016/j.cclet.2024.109584
7. [7]
  Biao Huang , Tao Tang , Fushou Liu , Shi-Hui Chen , Zhi-Ling Zhang , Mingxi Zhang , Ran Cui . Quantum dots boost large-view NIR-Ⅱ imaging with high fidelity for fluorescence-guided tumor surgery. Chinese Chemical Letters, 2024, 35(12): 109694-. doi: 10.1016/j.cclet.2024.109694
8. [8]
  Chuanfeng Fan , Jian Gao , Yingkai Gao , Xintong Yang , Gaoning Li , Xiaochun Wang , Fei Li , Jin Zhou , Haifeng Yu , Yi Huang , Jin Chen , Yingying Shan , Li Chen . A non-peptide-based chymotrypsin-targeted long-wavelength emission fluorescent probe with large Stokes shift and its application in bioimaging. Chinese Chemical Letters, 2024, 35(10): 109838-. doi: 10.1016/j.cclet.2024.109838
9. [9]
  Makhloufi Zoulikha , Zhongjian Chen , Jun Wu , Wei He . Approved delivery strategies for biopharmaceuticals. Chinese Chemical Letters, 2025, 36(2): 110225-. doi: 10.1016/j.cclet.2024.110225
10. [10]
  Jing Zhang , Charles Wang , Yaoyao Zhang , Haining Xia , Yujuan Wang , Kun Ma , Junfeng Wang . Application of magnetotactic bacteria as engineering microrobots: Higher delivery efficiency of antitumor medicine. Chinese Chemical Letters, 2024, 35(10): 109420-. doi: 10.1016/j.cclet.2023.109420
11. [11]
  Tong Tong , Lezong Chen , Siying Wu , Zhong Cao , Yuanbin Song , Jun Wu . Establishment of a leucine-based poly(ester amide)s library with self-anticancer effect as nano-drug carrier for colorectal cancer treatment. Chinese Chemical Letters, 2024, 35(12): 109689-. doi: 10.1016/j.cclet.2024.109689
12. [12]
  Jiaqi Huang , Renjiang Kong , Yanmei Li , Ni Yan , Yeyang Wu , Ziwen Qiu , Zhenming Lu , Xiaona Rao , Shiying Li , Hong Cheng . Feedback enhanced tumor targeting delivery of albumin-based nanomedicine to amplify photodynamic therapy by regulating AMPK signaling and inhibiting GSTs. Chinese Chemical Letters, 2024, 35(8): 109254-. doi: 10.1016/j.cclet.2023.109254
13. [13]
  Lihang Wang , Mary Li Javier , Chunshan Luo , Tingsheng Lu , Shudan Yao , Bing Qiu , Yun Wang , Yunfeng Lin . Research advances of tetrahedral framework nucleic acid-based systems in biomedicine. Chinese Chemical Letters, 2024, 35(11): 109591-. doi: 10.1016/j.cclet.2024.109591
14. [14]
  Bin Fang , Jiaqi Yang , Limin Wang , Haoqin Li , Jiaying Guo , Jiaxin Zhang , Qingyuan Guo , Bo Peng , Kedi Liu , Miaomiao Xi , Hua Bai , Li Fu , Lin Li . A mitochondria-targeted H₂S-activatable fluorogenic probe for tracking hepatic ischemia-reperfusion injury. Chinese Chemical Letters, 2024, 35(6): 108913-. doi: 10.1016/j.cclet.2023.108913
15. [15]
  Zengchao Guo , Weiwei Liu , Tengfei Liu , Jinpeng Wang , Hui Jiang , Xiaohui Liu , Yossi Weizmann , Xuemei Wang . Engineered exosome hybrid copper nanoscale antibiotics facilitate simultaneous self-assembly imaging and elimination of intracellular multidrug-resistant superbugs. Chinese Chemical Letters, 2024, 35(7): 109060-. doi: 10.1016/j.cclet.2023.109060
16. [16]
  Lixian Fu , Yiyun Tan , Yue Ding , Weixia Qing , Yong Wang . Water–soluble and polarity–sensitive near–infrared fluorescent probe for long–time specific cancer cell membranes imaging and C. Elegans label. Chinese Chemical Letters, 2024, 35(4): 108886-. doi: 10.1016/j.cclet.2023.108886
17. [17]
  Yunlong Li , Xinyu Zhang , Shuang Liu , Chunsheng Li , Qiang Wang , Jin Ye , Yong Lu , Jiating Xu . Engineered iron-based metal-organic frameworks nanoplatforms for cancer theranostics: A mini review. Chinese Chemical Letters, 2025, 36(2): 110501-. doi: 10.1016/j.cclet.2024.110501
18. [18]
  Haixian Ren , Yuting Du , Xiaojing Yang , Fangjun Huo , Le Zhang , Caixia Yin . Development of ESIPT-based specific fluorescent probes for bioactive species based on the protection-deprotection of the hydroxyl. Chinese Chemical Letters, 2025, 36(2): 109867-. doi: 10.1016/j.cclet.2024.109867
19. [19]
  Fan Zheng , Runsha Xiao , Shuai Huang , Zhikang Chen , Chen Lai , Anyao Bi , Heying Yao , Xueping Feng , Zihua Chen , Wenbin Zeng . Accurate visualization colorectal cancer by monitoring viscosity variations with a novel mitochondria-targeted fluorescent probe. Chinese Chemical Letters, 2025, 36(2): 109876-. doi: 10.1016/j.cclet.2024.109876
20. [20]
  Yong-Dan Zhao , Yidan Wang , Rongrong Wang , Lina Chen , Hengtong Zuo , Xi Wang , Jihong Qiang , Geng Wang , Qingxia Li , Canqi Ping , Shuqiu Zhang , Hao Wang . Reversing artemisinin resistance by leveraging thermo-responsive nanoplatform to downregulating GSH. Chinese Chemical Letters, 2024, 35(6): 108929-. doi: 10.1016/j.cclet.2023.108929

Get Citation

PDF

XML

Metrics

PDF Downloads(19)
Abstract views(740)
HTML views(177)

通讯作者: 陈斌, bchen63@163.com

1.
沈阳化工大学材料科学与工程学院沈阳 110142