Citation: Zhen Zhang, Fang Chen, Jiwen Feng, Junfei Chen, Li Chen, Zhi Zhang, Huijuan Wang, Xin Cheng, Maili Liu, Chaoyang Liu. −22-Fold of ¹H signal enhancement in-situ low-field liquid NMR using nanodiamond as polarizer of overhauser dynamic nuclear polarization[J]. Chinese Chemical Letters, ;2021, 32(11): 3483-3486. doi: 10.1016/j.cclet.2021.05.068 shu

−22-Fold of ¹H signal enhancement in-situ low-field liquid NMR using nanodiamond as polarizer of overhauser dynamic nuclear polarization

Zhen Zhang ^{a, b} ,
Fang Chen ^{a, b, *,} ,
Jiwen Feng ^{a, b} ,
Junfei Chen ^{a, b} ,
Li Chen ^{a, b} ,
Zhi Zhang ^{a, b} ,
Huijuan Wang ^{a, b} ,
Xin Cheng ^{a, b} ,
Maili Liu ^{a, b, c} ,
Chaoyang Liu ^{a, b, c, *,}

a.
State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan Center for Magnetic Resonance, Wuhan Institute of Physics and Mathematics, Innovation Academy for Precision Measurement Science and Technology, Chinese Academy of Sciences, Wuhan 430071, China
b.
University of Chinese Academy of Sciences, Beijing 100049, China
c.
Wuhan National Laboratory for Optoelectronics, Huazhong University of Science and Technology, Wuhan 430074, China

chenfang@wipm.ac.cn

chyliu@wipm.ac.cn

Received Date: 3 February 2021
Revised Date: 17 March 2021
Accepted Date: 28 May 2021
Available Online: 31 May 2021

Figures(2)

Nanodiamond (ND) polarizer can be used for dynamic nuclear polarization (DNP), owing to unpaired electrons provided by surface defects. However, ¹H enhancement via Overhauser DNP (ODNP) using ND in-situ liquid has been found much smaller than traditional radicals. Herein, we study the surface properties of ND using electron spin resonance (ESR) and Raman methods firstly. Then the enhancement of ¹H ODNP is explored using ND as polarizer with different nanoparticle sizes and concentrations at home-built 0.06 T DNP spectrometer. The surface of ND with the size of 30 nm is further modification via high temperature air oxidized and the enhancement was measured. The results show that nanoparticle sizes and Raman peak intensity ratio of sp²/sp³ hybridization are approximate negative correlation and positive correlation to enhancement, respectively. Furthermore, there is no significant enhancement in the oxidation group, and a −22.5-fold ¹H ODNP enhancement is achieved in-situ liquid at room temperature, which demonstrate the ND can be used as an efficient enhancer. We expect ND to play a greater role in biomedical research, especially for multimodal imaging with improving the performance of ND surface.
- ODNP,
- Polarizer,
- Nanoparticle,
- Enhancement,
- Relaxation
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−22-Fold of 1H signal enhancement in-situ low-field liquid NMR using nanodiamond as polarizer of overhauser dynamic nuclear polarization

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通讯作者: 陈斌, bchen63@163.com

−22-Fold of ¹H signal enhancement in-situ low-field liquid NMR using nanodiamond as polarizer of overhauser dynamic nuclear polarization