Citation: Yuting Wang, Shu Zhang, Jian Wang. Photo-crosslinkable hydrogel and its biological applications[J]. Chinese Chemical Letters, ;2021, 32(5): 1603-1614. doi: 10.1016/j.cclet.2020.11.073 shu

Photo-crosslinkable hydrogel and its biological applications

Yuting Wang ^{a, b} ,
Shu Zhang ^{a, b} ,
Jian Wang ^{a, b, *,}

a.
State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, West China Hospital of Stomatology, Sichuan University, Chengdu 610041, China
b.
West China School of Stomatology, Sichuan University, Chengdu 610041, China

ferowang@hotmail.com

Received Date: 17 September 2020
Revised Date: 10 November 2020
Accepted Date: 11 November 2020
Available Online: 4 December 2020

Figures(4)

In the past few years, photo-crosslinkable hydrogels have drawn a great attention in tissue engineering applications due to their high biocompatibility and extracellular matrix (ECM)-like structure. They can be easily biofabricated through exposure of a photosensitive system composed of photo-crosslinkable hydrogels, photo-initiators and other compounds such as cells and therapeutic molecules, to ultraviolet or visible light. With the development of biofabrication methods, many researchers studied the biological applications of photo-crosslinkable hydrogels in tissue engineering, such as vascular, wound dressing and bone engineering. This review highlights the biomaterials for photo-crosslinkable hydrogels, biofabrication techniques and their biological applications in tissue engineering. Meanwhile, the challenges and prospects of photo-crosslinkable hydrogels are discussed as well.
- Photo-crosslinkable,
- Biomaterial,
- Hydrogel,
- Biofabrication,
- Biological application
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