Citation: Zhang Zijie, Bragg Leslie M., Servos Mark R., Liu Juewen. Gold nanoparticles as dehydrogenase mimicking nanozymes for estradiol degradation[J]. Chinese Chemical Letters, ;2019, 30(9): 1655-1658. doi: 10.1016/j.cclet.2019.05.062 shu

Gold nanoparticles as dehydrogenase mimicking nanozymes for estradiol degradation

a.
Department of Chemistry, Waterloo Institute for Nanotechnology, University of Waterloo, Waterloo, Ontario, N2L 3G1, Canada
b.
Department of Biology, University of Waterloo, Waterloo, Ontario, N2L 3G1, Canada

liujw@uwaterloo.ca

Received Date: 25 April 2019
Revised Date: 30 May 2019
Accepted Date: 30 May 2019
Available Online: 1 October 2019

Figures(5)

Nanozyme catalysis has been mainly focused on a few chromogenic and fluorogenic substrates, while environmentally and biologically important compounds need to be tested to advance the field. In this work, we studied oxidation of estradiol (E2) in the presence of various nanomaterials including gold nanoparticles (AuNPs), nanoceria (CeO₂), Fe₃O₄, Fe₂O₃, MnO₂ and Mn₂O₃, and found that AuNPs had a dehydrogenase-mimicking activity to convert E2 to estrone (E1). This conversion was monitored using HPLC. The reaction was faster at higher pH and reached saturation at pH 8. Smaller AuNPs had a higher catalytic efficiency and 5 nm AuNPs were 4.8-fold faster than 13 nm at the same total surface area. Finally, we tried 17α-ethinylestradiol (EE2) as a substrate and found that 5 nm AuNPs can catalyze EE2 oxidation in the presence of H₂O₂. This work indicated that some nanomaterials can affect environmentally important hormones via oxidation reactions, and this study has expanded the scope of substrate of nanozymes.
- Nanozymes,
- Estradiol,
- Gold nanoparticles,
- Catalysis,
- Environment,
- HPLC
1. [1]
  C.J. Gruber, W. Tschugguel, C. Schneeberger, et al., N. Engl. J. Med. 346(2002) 340-352. doi: 10.1056/NEJMra000471
2. [2]
  H.G. Burger, Fertil. Steril. 77(2002) 3-5.
3. [3]
  V.N. Luine, Horm. Behav. 66(2014) 602-618. doi: 10.1016/j.yhbeh.2014.08.011
4. [4]
  M. Adeel, X. Song, Y. Wang, et al., Environ. Int. 99(2017) 107-119. doi: 10.1016/j.envint.2016.12.010
5. [5]
  T.F.T. Omar, A. Ahmad, A.Z. Aris, et al., TrAC-Trends Anal. Chem. 85(2016) 241-259. doi: 10.1016/j.trac.2016.08.004
6. [6]
  R.N. Tanna, G.R. Tetreault, C.J. Bennett, et al., Environ. Toxicol. Chem. 32(2013) 1981-1991. doi: 10.1002/etc.2262
7. [7]
  M. Giulivo, M.L. de Alda, E. Capri, et al., Environ. Res. 151(2016) 251-264. doi: 10.1016/j.envres.2016.07.011
8. [8]
  C. Zhang, Y. Li, C. Wang, et al., Crit. Rev. Environ. Sci. Technol. 46(2016) 1-59. doi: 10.1080/10643389.2015.1061881
9. [9]
  F. Itzel, K.S. Jewell, J. Leonhardt, et al., Sci. Total Environ. 624(2018) 1443-1454. doi: 10.1016/j.scitotenv.2017.12.181
10. [10]
  A. Roudbari, M. Rezakazemi, AMB Express 8(2018) 91. doi: 10.1186/s13568-018-0621-4
11. [11]
  Z. Zhang, Y. Feng, Y. Liu, et al., J. Hazard. Mater. 181(2010) 1127-1133. doi: 10.1016/j.jhazmat.2010.05.132
12. [12]
  K. Sornalingam, A. McDonagh, J.L. Zhou, Sci. Total Environ. 550(2016) 209-224. doi: 10.1016/j.scitotenv.2016.01.086
13. [13]
  M.V. de Liz, R.M. de Lima, B. do Amaral, et al., J. Braz. Chem. Soc. 29(2018) 380-389.
14. [14]
  Y. Huang, J. Ren, X. Qu, Chem. Rev. 119(2019) 4357-4412. doi: 10.1021/acs.chemrev.8b00672
15. [15]
  Y. Zhou, B. Liu, R. Yang, et al., Bioconj. Chem. 28(2017) 2903-2909. doi: 10.1021/acs.bioconjchem.7b00673
16. [16]
  J. Wu, X. Wang, Q. Wang, et al., Chem. Soc. Rev. 48(2019) 1004-1076. doi: 10.1039/C8CS00457A
17. [17]
  S. Lin, H. Wei, Sci. China-Life Sci. 62(2019) 710-712. doi: 10.1007/s11427-019-9518-0
18. [18]
  G. Zhang, R. Wang, G. Li, Chin. Chem. Lett. 29(2018) 687-693. doi: 10.1016/j.cclet.2018.01.043
19. [19]
  W. Luo, C. Zhu, S. Su, et al., ACS Nano 4(2010) 7451-7458. doi: 10.1021/nn102592h
20. [20]
  M. Comotti, C. Della Pina, R. Matarrese, et al., Angew. Chem. Int. Ed. 43(2004) 5812-5815. doi: 10.1002/anie.200460446
21. [21]
  L. Gao, J. Zhuang, L. Nie, et al., Nat. Nanotechnol. 2(2007) 577-583. doi: 10.1038/nnano.2007.260
22. [22]
  A. Asati, S. Santra, C. Kaittanis, et al., Angew. Chem. Int. Ed. 48(2009) 2308-2312. doi: 10.1002/anie.200805279
23. [23]
  M. Liu, Z. Li, Y. Li, J. Chen, Q. Yuan, Chin. Chem. Lett. 30(2019) 1009-1012. doi: 10.1016/j.cclet.2018.12.021
24. [24]
  B. Liu, J. Liu, Nano Res. 10(2017) 1125-1148. doi: 10.1007/s12274-017-1426-5
25. [25]
  Y. Hu, H. Cheng, X. Zhao, et al., ACS Nano 11(2017) 5558-5566. doi: 10.1021/acsnano.7b00905
26. [26]
  T. Yu, B. Liu, J. Liu, J. Anal. Test. 1(2017) 2. doi: 10.1007/s41664-017-0001-0
27. [27]
  L.Z. Gao, K.L. Fan, X.Y. Yan, Theranostics 7(2017) 3207-3227. doi: 10.7150/thno.19738
28. [28]
  X. Wang, Y. Hu, H. Wei, Inorg. Chem. Front. 3(2016) 41-60. doi: 10.1039/C5QI00240K
29. [29]
  Z. Liu, X. Qu, Sci. China-Life Sci. 62(2019) 150-152. doi: 10.1007/s11427-018-9417-1
30. [30]
  L. Yu, Y. Chen, H. Chen, Chin. Chem. Lett. 28(2017) 1841-1850. doi: 10.1016/j.cclet.2017.05.023
31. [31]
  Z. Zhang, X. Zhang, B. Liu, et al., J. Am. Chem. Soc. 139(2017) 5412-5419. doi: 10.1021/jacs.7b00601
32. [32]
  B. Liu, Z. Huang, J. Liu, Nanoscale 8(2016) 13562-13567. doi: 10.1039/C6NR02730J
33. [33]
  Y. Biniuri, B. Albada, M. Wolff, et al., ACS Catal. 8(2018) 1802-1809. doi: 10.1021/acscatal.7b03454
34. [34]
  M. Vazquez-Gonzalez, R.M. Torrente-Rodriguez, A. Kozell, et al., Nano Lett. 17(2017) 4958-4963. doi: 10.1021/acs.nanolett.7b02102
35. [35]
  M.S. Hizir, M. Top, M. Balcioglu, et al., Anal. Chem. 88(2016) 600-605. doi: 10.1021/acs.analchem.5b03926
36. [36]
  D. Li, B. Liu, P.J.J. Huang, et al., Chem. Commun. 54(2018) 12519-12522. doi: 10.1039/C8CC07062H
37. [37]
  X.L. Ren, M.Q. Wang, X. He, et al., Chin. Chem. Lett. 29(2018) 1865-1868. doi: 10.1016/j.cclet.2018.12.007
38. [38]
  H. Liang, F. Lin, Z. Zhang, et al., ACS Appl. Mater. Interfaces 9(2017) 1352-1360. doi: 10.1021/acsami.6b15124
39. [39]
  C.I. Wang, W.T. Chen, H.T. Chang, Anal. Chem. 84(2012) 9706-9712. doi: 10.1021/ac300867s
40. [40]
  J.H. Xu, C.G. Hu, S.S. Hu, Chin. Chem. Lett. 20(2009) 1248-1250. doi: 10.1016/j.cclet.2009.04.019
41. [41]
  B. Liu, J. Liu, ACS Appl. Mater. Interfaces 7(2015) 24833-24838. doi: 10.1021/acsami.5b08004
42. [42]
  M.J. Arlos, W.J. Parker, J.R. Bicudo, et al., Sci. Total Environ. 610(2018) 1103-1112.
43. [43]
  M.J.Arlos, R.Liang, M.M.Hatat-Fraile, etal., J.Hazard.Mater.318(2016)541-550. doi: 10.1016/j.jhazmat.2016.07.048
44. [44]
  C. Della Pina, E. Falletta, L. Prati, et al., Chem. Soc. Rev. 37(2008) 2077-2095. doi: 10.1039/b707319b
45. [45]
  T. Mallat, A. Baiker, Annu. Rev. Chem. Biomol. Eng. 3(2012) 11-28. doi: 10.1146/annurev-chembioeng-062011-081046
46. [46]
  H. Kuhl, Climacteric 8(2005) 3-63.
47. [47]
  M.M. Miettinen, M.V. Mustonen, M.H. Poutanen, et al., Biochem. J. 314(1996) 839-845. doi: 10.1042/bj3140839
48. [48]
  G.D. Sheng, C. Xu, L. Xu, et al., Environ. Pollut. 157(2009) 2710-2715. doi: 10.1016/j.envpol.2009.04.030
49. [49]
  L.L. Engel, E.V. Groman, Human placental 17β-estradiol dehydrogenase: Characterization and structural studies, Proceedings of the 1973 Laurentian Hormone Conference, Elsevier, 1974, pp. 139-169.
50. [50]
  R. Breton, D. Housset, C. Mazza, et al., Structure 4(1996) 905-915. doi: 10.1016/S0969-2126(96)00098-6
51. [51]
  N.J. Lang, B. Liu, J. Liu, J. Colloid Interface Sci. 428(2014) 78-83. doi: 10.1016/j.jcis.2014.04.025
52. [52]
  K. Lewis, R. Archer, Steroids 34(1979) 485-499. doi: 10.1016/S0039-128X(79)80011-2
53. [53]
  A. Kumar, S. Mandal, P. Selvakannan, et al., Langmuir 19(2003) 6277-6282. doi: 10.1021/la034209c
54. [54]
  J. Liu, Phys. Chem. Chem. Phys. 14(2012) 10485-10496. doi: 10.1039/c2cp41186e
55. [55]
  Y. Lin, J. Ren, X. Qu, Adv. Mater. 26(2014) 4200-4217. doi: 10.1002/adma.201400238
56. [56]
  Z. Qing, L. Zhu, S. Yang, et al., Biosens. Bioelectron. 78(2016) 471-476. doi: 10.1016/j.bios.2015.11.057
57. [57]
  D. Wang, B. Huang, J. Liu, et al., Biosens. Bioelectron. 102(2018) 389-395. doi: 10.1016/j.bios.2017.11.051
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