Citation: Xian Caihong, Yuan Qijuan, Bao Ziting, Liu Guiting, Wu Jun. Progress on intelligent hydrogels based on RAFT polymerization: Design strategy, fabrication and the applications for controlled drug delivery[J]. Chinese Chemical Letters, ;2020, 31(1): 19-27. doi: 10.1016/j.cclet.2019.03.052 shu

Progress on intelligent hydrogels based on RAFT polymerization: Design strategy, fabrication and the applications for controlled drug delivery

Xian Caihong ^a ,
Yuan Qijuan ^a ,
Bao Ziting ^a ,
Liu Guiting ^a,** ,
Wu Jun ^a,b,*

a.
Key Laboratory of Sensing Technology and Biomedical Instrument of Guangdong Province, School of Biomedical Engineering, Sun Yat-sen University, Guangzhou 510006, China
b.
Research Institute of Sun Yat-Sen University in Shenzhen, Shenzhen 518057, China

^**

liugt3@mail.sysu.edu.cn

wujun29@mail.sysu.edu.cn

Received Date: 2 March 2019
Revised Date: 25 March 2019
Accepted Date: 28 March 2019
Available Online: 28 January 2019

Figures(14)

Although intelligent hydrogels have shown bright potential application in biomedical fields, they were prepared by conventional methods and still face many serious challenges, such as uncontrollable stimulus-response and low response sensitivity. Recently, RAFT polymerization provides a versatile strategy for the fabrication of intelligent hydrogels with improved stimulus-response properties, owing to the ability to efficiently construct hydrogel precursors with well-defined structure, such as block copolymer, graft copolymer, star copolymer. In this review, we summarized the recent progress on intelligent hydrogels based on RAFT polymerization with emphasis on their fabrication strategies and applications for controlled drug delivery.
- timulus-responsive,
- Hydrogel,
- RAFT polymerization,
- Drug controlled release,
- Rapid response
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